Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/28174 https://dx.doi.org/10.1590/S1413-86702011000300019 |
Resumo: | Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion. |
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Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosumHIV (Vírus)PneumoniaMortalidadeAureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.Em processamentoBrazilian Society of Infectious Diseases2017-12-07T04:57:13Z2017-12-07T04:57:13Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBraz J Infect Dis,v.15,n.3,p.288-292,2011http://repositorio.unb.br/handle/10482/28174https://dx.doi.org/10.1590/S1413-86702011000300019Morais, Orlando Oliveira dePorto, CláudiaCoutinho, Anglya Samara Silva LeiteReis, Carmélia Matos SantiagoTeixeira, Marcus de MeloGomes, Ciro Martinsinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-08-28T16:24:50Zoai:repositorio.unb.br:10482/28174Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-28T16:24:50Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
spellingShingle |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum Morais, Orlando Oliveira de HIV (Vírus) Pneumonia Mortalidade |
title_short |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_full |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_fullStr |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_full_unstemmed |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
title_sort |
Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum |
author |
Morais, Orlando Oliveira de |
author_facet |
Morais, Orlando Oliveira de Porto, Cláudia Coutinho, Anglya Samara Silva Leite Reis, Carmélia Matos Santiago Teixeira, Marcus de Melo Gomes, Ciro Martins |
author_role |
author |
author2 |
Porto, Cláudia Coutinho, Anglya Samara Silva Leite Reis, Carmélia Matos Santiago Teixeira, Marcus de Melo Gomes, Ciro Martins |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Morais, Orlando Oliveira de Porto, Cláudia Coutinho, Anglya Samara Silva Leite Reis, Carmélia Matos Santiago Teixeira, Marcus de Melo Gomes, Ciro Martins |
dc.subject.por.fl_str_mv |
HIV (Vírus) Pneumonia Mortalidade |
topic |
HIV (Vírus) Pneumonia Mortalidade |
description |
Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011 2017-12-07T04:57:13Z 2017-12-07T04:57:13Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Braz J Infect Dis,v.15,n.3,p.288-292,2011 http://repositorio.unb.br/handle/10482/28174 https://dx.doi.org/10.1590/S1413-86702011000300019 |
identifier_str_mv |
Braz J Infect Dis,v.15,n.3,p.288-292,2011 |
url |
http://repositorio.unb.br/handle/10482/28174 https://dx.doi.org/10.1590/S1413-86702011000300019 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
instacron_str |
UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
_version_ |
1814508405581152256 |