Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum

Detalhes bibliográficos
Autor(a) principal: Morais, Orlando Oliveira de
Data de Publicação: 2011
Outros Autores: Porto, Cláudia, Coutinho, Anglya Samara Silva Leite, Reis, Carmélia Matos Santiago, Teixeira, Marcus de Melo, Gomes, Ciro Martins
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/28174
https://dx.doi.org/10.1590/S1413-86702011000300019
Resumo: Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
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spelling Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosumHIV (Vírus)PneumoniaMortalidadeAureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.Em processamentoBrazilian Society of Infectious Diseases2017-12-07T04:57:13Z2017-12-07T04:57:13Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBraz J Infect Dis,v.15,n.3,p.288-292,2011http://repositorio.unb.br/handle/10482/28174https://dx.doi.org/10.1590/S1413-86702011000300019Morais, Orlando Oliveira dePorto, CláudiaCoutinho, Anglya Samara Silva LeiteReis, Carmélia Matos SantiagoTeixeira, Marcus de MeloGomes, Ciro Martinsinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-08-28T16:24:50Zoai:repositorio.unb.br:10482/28174Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-28T16:24:50Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
spellingShingle Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Morais, Orlando Oliveira de
HIV (Vírus)
Pneumonia
Mortalidade
title_short Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_full Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_fullStr Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_full_unstemmed Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
title_sort Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
author Morais, Orlando Oliveira de
author_facet Morais, Orlando Oliveira de
Porto, Cláudia
Coutinho, Anglya Samara Silva Leite
Reis, Carmélia Matos Santiago
Teixeira, Marcus de Melo
Gomes, Ciro Martins
author_role author
author2 Porto, Cláudia
Coutinho, Anglya Samara Silva Leite
Reis, Carmélia Matos Santiago
Teixeira, Marcus de Melo
Gomes, Ciro Martins
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Morais, Orlando Oliveira de
Porto, Cláudia
Coutinho, Anglya Samara Silva Leite
Reis, Carmélia Matos Santiago
Teixeira, Marcus de Melo
Gomes, Ciro Martins
dc.subject.por.fl_str_mv HIV (Vírus)
Pneumonia
Mortalidade
topic HIV (Vírus)
Pneumonia
Mortalidade
description Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
publishDate 2011
dc.date.none.fl_str_mv 2011
2017-12-07T04:57:13Z
2017-12-07T04:57:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Braz J Infect Dis,v.15,n.3,p.288-292,2011
http://repositorio.unb.br/handle/10482/28174
https://dx.doi.org/10.1590/S1413-86702011000300019
identifier_str_mv Braz J Infect Dis,v.15,n.3,p.288-292,2011
url http://repositorio.unb.br/handle/10482/28174
https://dx.doi.org/10.1590/S1413-86702011000300019
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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