Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment

Detalhes bibliográficos
Autor(a) principal: Garcia,Rosa
Data de Publicação: 2005
Outros Autores: Pondé,Milena, Lima,Manuela, Souza,Alba Regina de, Stolze,Silvia Maria de O., Badaró,Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600007
Resumo: As a result of the potent drug combinations of reverse transcriptase inhibitors and protease inhibitors currently available, it is now possible to achieve extreme reductions in the numbers of viral particles in the peripheral blood of HIV-positive patients undergoing treatment, to the point that they are undetectable. Moreover, the immunological recovery resulting from continued and prolonged use of these drugs significantly reduces both mortality and the incidence of opportunistic infections. However, the strict therapeutic regimens required, the number of pills, adverse events and the stigma of a disease that requires the patient to introduce pill-taking into his/her lifestyle brings into question one aspect of mental health, which is motivation to do that which is being proposed. We investigated the influence of each of the components of the adherence trilogy: information, motivation and behavioral abilities, as risk factors in a population of HIV-positive/AIDS patients undergoing antiretroviral treatment in the city of Salvador, Bahia, Brazil. MATERIAL AND METHODS: An intervention study was carried out by introducing motivational assistance into the routine recommendations for the treatment of patients who were initiating antiretroviral (ARV) therapy. Seventy-six treatment-naive patients, who had been selected to initiate ARV therapy, were included. These patients were divided into two groups. Group A, in which the regular routine of the institution was followed, received information on the disease and its treatment;patients in group B had the same routine, but they were also followed-up fortnightly and given motivational intervention. Evaluations of viral load and CD4 count before and following treatment were used to measure adherence. RESULTS: There was no significant difference between the two groups. CONCLUSIONS: As the rates of non-adhesion were at the lower limits of the ranges reported in the literature, it would appear that providing motivation and information can be of help to the patient.
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spelling Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatmentMotivationadherenceHIV-Positive/AIDStreatmentAs a result of the potent drug combinations of reverse transcriptase inhibitors and protease inhibitors currently available, it is now possible to achieve extreme reductions in the numbers of viral particles in the peripheral blood of HIV-positive patients undergoing treatment, to the point that they are undetectable. Moreover, the immunological recovery resulting from continued and prolonged use of these drugs significantly reduces both mortality and the incidence of opportunistic infections. However, the strict therapeutic regimens required, the number of pills, adverse events and the stigma of a disease that requires the patient to introduce pill-taking into his/her lifestyle brings into question one aspect of mental health, which is motivation to do that which is being proposed. We investigated the influence of each of the components of the adherence trilogy: information, motivation and behavioral abilities, as risk factors in a population of HIV-positive/AIDS patients undergoing antiretroviral treatment in the city of Salvador, Bahia, Brazil. MATERIAL AND METHODS: An intervention study was carried out by introducing motivational assistance into the routine recommendations for the treatment of patients who were initiating antiretroviral (ARV) therapy. Seventy-six treatment-naive patients, who had been selected to initiate ARV therapy, were included. These patients were divided into two groups. Group A, in which the regular routine of the institution was followed, received information on the disease and its treatment;patients in group B had the same routine, but they were also followed-up fortnightly and given motivational intervention. Evaluations of viral load and CD4 count before and following treatment were used to measure adherence. RESULTS: There was no significant difference between the two groups. CONCLUSIONS: As the rates of non-adhesion were at the lower limits of the ranges reported in the literature, it would appear that providing motivation and information can be of help to the patient.Brazilian Society of Infectious Diseases2005-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600007Brazilian Journal of Infectious Diseases v.9 n.6 2005reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702005000600007info:eu-repo/semantics/openAccessGarcia,RosaPondé,MilenaLima,ManuelaSouza,Alba Regina deStolze,Silvia Maria de O.Badaró,Robertoeng2006-01-09T00:00:00Zoai:scielo:S1413-86702005000600007Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2006-01-09T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
title Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
spellingShingle Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
Garcia,Rosa
Motivation
adherence
HIV-Positive/AIDS
treatment
title_short Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
title_full Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
title_fullStr Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
title_full_unstemmed Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
title_sort Lack of effect of motivation on the adherence of HIV-positive/AIDS patients to antiretroviral treatment
author Garcia,Rosa
author_facet Garcia,Rosa
Pondé,Milena
Lima,Manuela
Souza,Alba Regina de
Stolze,Silvia Maria de O.
Badaró,Roberto
author_role author
author2 Pondé,Milena
Lima,Manuela
Souza,Alba Regina de
Stolze,Silvia Maria de O.
Badaró,Roberto
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Garcia,Rosa
Pondé,Milena
Lima,Manuela
Souza,Alba Regina de
Stolze,Silvia Maria de O.
Badaró,Roberto
dc.subject.por.fl_str_mv Motivation
adherence
HIV-Positive/AIDS
treatment
topic Motivation
adherence
HIV-Positive/AIDS
treatment
description As a result of the potent drug combinations of reverse transcriptase inhibitors and protease inhibitors currently available, it is now possible to achieve extreme reductions in the numbers of viral particles in the peripheral blood of HIV-positive patients undergoing treatment, to the point that they are undetectable. Moreover, the immunological recovery resulting from continued and prolonged use of these drugs significantly reduces both mortality and the incidence of opportunistic infections. However, the strict therapeutic regimens required, the number of pills, adverse events and the stigma of a disease that requires the patient to introduce pill-taking into his/her lifestyle brings into question one aspect of mental health, which is motivation to do that which is being proposed. We investigated the influence of each of the components of the adherence trilogy: information, motivation and behavioral abilities, as risk factors in a population of HIV-positive/AIDS patients undergoing antiretroviral treatment in the city of Salvador, Bahia, Brazil. MATERIAL AND METHODS: An intervention study was carried out by introducing motivational assistance into the routine recommendations for the treatment of patients who were initiating antiretroviral (ARV) therapy. Seventy-six treatment-naive patients, who had been selected to initiate ARV therapy, were included. These patients were divided into two groups. Group A, in which the regular routine of the institution was followed, received information on the disease and its treatment;patients in group B had the same routine, but they were also followed-up fortnightly and given motivational intervention. Evaluations of viral load and CD4 count before and following treatment were used to measure adherence. RESULTS: There was no significant difference between the two groups. CONCLUSIONS: As the rates of non-adhesion were at the lower limits of the ranges reported in the literature, it would appear that providing motivation and information can be of help to the patient.
publishDate 2005
dc.date.none.fl_str_mv 2005-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-86702005000600007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.9 n.6 2005
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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