Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/2281 |
Resumo: | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento Ciência Social. Rio de Janeiro, RJ, Brasil |
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Malta, Monica SiqueiraMagnanini, Monica Maria FerreiraSteffanie A. StrathdeeBastos, Francisco Inácio Pinkusfeld Monteiro2011-05-02T18:28:44Z2011-05-02T18:28:44Z2010MALTA, Monica Siqueira et. al. Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysisAIDS and Behavior, v.14, p.731–747, 2010.1573-3254https://www.arca.fiocruz.br/handle/icict/228110.1007/s10461-008-9489-7engElsevierAdherence to antiretroviral therapy among HIV-infected drug users: a meta-analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento Ciência Social. Rio de Janeiro, RJ, BrasilUniversidade Federal do Rio de Janeiro. Instituto de Estudos de Saúde Coletiva. Rio de Janeiro, RJ, BrasilUniversity of California. School of Medicine, San Diego. Division of International Health and Cross Cultural Medicine. Department of Family and Preventive Medicine. San Diego, CA, USA.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Laboratório de Informação em Saúde. Rio de Janeiro, RJ, BrasilAbstract We conducted a meta-analysis of studies assessing adherence to highly active antiretroviral therapy (HAART) and a qualitative systematic review of factors associated with better HAART outcomes among HIV? drug users (DU). Thirty-eight studies were considered, which analyzed 14,960 patients (11,394 HIV? DU, 76.2%). Overall adherence (pooled percent of DU classified as adherent in each study) was 0.60 (95% CI: 0.52– 0.68), similar to levels identified by studies conducted with HIV? patients who are not drug users. Time frame used to measure adherence was an independent predictor of interstudy heterogeneity. The systematic review identified better HAART outcomes among former DU, those with less severe psychiatric conditions, those receiving opioid substitution therapy and/or psychosocial support. Patients initiating HAART with lower viral load and higher CD4 counts, and those without co-infections also had better treatment outcomes. Our findings suggest that HIV? DU tend to be inappropriately assumed to be less adherent and unlikely to achieve desirable treatment outcomes, when compared to their non-DU cohort.HIVAidsMeta-analysisAdherenceDrug useinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALAdherence to Antiretroviral_2010.pdfAdherence to Antiretroviral_2010.pdfapplication/pdf384714https://www.arca.fiocruz.br/bitstream/icict/2281/1/Adherence%20to%20Antiretroviral_2010.pdfcd062b61d620faccaefbf9db80ba5796MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2281/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTAdherence to Antiretroviral_2010.pdf.txtAdherence to Antiretroviral_2010.pdf.txtExtracted texttext/plain73313https://www.arca.fiocruz.br/bitstream/icict/2281/5/Adherence%20to%20Antiretroviral_2010.pdf.txt925aed8b3c8e9ca1b7916f08a761a6d5MD55THUMBNAILAdherence to Antiretroviral_2010.pdf.jpgAdherence to Antiretroviral_2010.pdf.jpgGenerated Thumbnailimage/jpeg2084https://www.arca.fiocruz.br/bitstream/icict/2281/4/Adherence%20to%20Antiretroviral_2010.pdf.jpg35c9f21d1612002cd0cdc63434bc99a0MD54icict/22812023-08-23 15:29:34.311oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-08-23T18:29:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
title |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
spellingShingle |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis Malta, Monica Siqueira HIV Aids Meta-analysis Adherence Drug use |
title_short |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
title_full |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
title_fullStr |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
title_full_unstemmed |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
title_sort |
Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis |
author |
Malta, Monica Siqueira |
author_facet |
Malta, Monica Siqueira Magnanini, Monica Maria Ferreira Steffanie A. Strathdee Bastos, Francisco Inácio Pinkusfeld Monteiro |
author_role |
author |
author2 |
Magnanini, Monica Maria Ferreira Steffanie A. Strathdee Bastos, Francisco Inácio Pinkusfeld Monteiro |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Malta, Monica Siqueira Magnanini, Monica Maria Ferreira Steffanie A. Strathdee Bastos, Francisco Inácio Pinkusfeld Monteiro |
dc.subject.en.pt_BR.fl_str_mv |
HIV Aids Meta-analysis Adherence Drug use |
topic |
HIV Aids Meta-analysis Adherence Drug use |
description |
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento Ciência Social. Rio de Janeiro, RJ, Brasil |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2011-05-02T18:28:44Z |
dc.date.available.fl_str_mv |
2011-05-02T18:28:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MALTA, Monica Siqueira et. al. Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysisAIDS and Behavior, v.14, p.731–747, 2010. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/2281 |
dc.identifier.issn.none.fl_str_mv |
1573-3254 |
dc.identifier.doi.none.fl_str_mv |
10.1007/s10461-008-9489-7 |
identifier_str_mv |
MALTA, Monica Siqueira et. al. Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysisAIDS and Behavior, v.14, p.731–747, 2010. 1573-3254 10.1007/s10461-008-9489-7 |
url |
https://www.arca.fiocruz.br/handle/icict/2281 |
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eng |
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eng |
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Elsevier |
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Elsevier |
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