Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Arquivos brasileiros de oftalmologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257 |
Resumo: | ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment. |
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Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaksAngioid streaksAntibodies, monoclonal/therapeutic useAntibodies, monoclonal/drug effectsAntibodies, monoclonal, humanized/drug effectsChoroidal neovascularization/drug therapyCase reportsABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.Conselho Brasileiro de Oftalmologia2015-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257Arquivos Brasileiros de Oftalmologia v.78 n.4 2015reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20150067info:eu-repo/semantics/openAccessYolcu,UmitGundogan,Fatih C.Diner,Oktayeng2015-09-09T00:00:00Zoai:scielo:S0004-27492015000400257Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2015-09-09T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false |
dc.title.none.fl_str_mv |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
title |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
spellingShingle |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks Yolcu,Umit Angioid streaks Antibodies, monoclonal/therapeutic use Antibodies, monoclonal/drug effects Antibodies, monoclonal, humanized/drug effects Choroidal neovascularization/drug therapy Case reports |
title_short |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
title_full |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
title_fullStr |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
title_full_unstemmed |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
title_sort |
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks |
author |
Yolcu,Umit |
author_facet |
Yolcu,Umit Gundogan,Fatih C. Diner,Oktay |
author_role |
author |
author2 |
Gundogan,Fatih C. Diner,Oktay |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Yolcu,Umit Gundogan,Fatih C. Diner,Oktay |
dc.subject.por.fl_str_mv |
Angioid streaks Antibodies, monoclonal/therapeutic use Antibodies, monoclonal/drug effects Antibodies, monoclonal, humanized/drug effects Choroidal neovascularization/drug therapy Case reports |
topic |
Angioid streaks Antibodies, monoclonal/therapeutic use Antibodies, monoclonal/drug effects Antibodies, monoclonal, humanized/drug effects Choroidal neovascularization/drug therapy Case reports |
description |
ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/0004-2749.20150067 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Conselho Brasileiro de Oftalmologia |
publisher.none.fl_str_mv |
Conselho Brasileiro de Oftalmologia |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Oftalmologia v.78 n.4 2015 reponame:Arquivos brasileiros de oftalmologia (Online) instname:Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO |
instname_str |
Conselho Brasileiro de Oftalmologia (CBO) |
instacron_str |
CBO |
institution |
CBO |
reponame_str |
Arquivos brasileiros de oftalmologia (Online) |
collection |
Arquivos brasileiros de oftalmologia (Online) |
repository.name.fl_str_mv |
Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO) |
repository.mail.fl_str_mv |
aboonline@cbo.com.br||abo@cbo.com.br |
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1754209028610719744 |