Intrastromal injection of bevacizumab in patients with corneal neovascularization

Detalhes bibliográficos
Autor(a) principal: Vieira,Ana Carolina Cabreira
Data de Publicação: 2012
Outros Autores: Höfling-Lima,Ana Luisa, Gomes,José Álvaro P., Freitas,Denise de, Farah,Michel Eid, Belfort Jr.,Rubens
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000400012
Resumo: Corneal neovascularization (NV) not only reduces visual acuity, but it also causes loss of the cornea's immune privilege, strongly contributing to a worse prognosis in penetrating keratoplasty. Several mediators participate in corneal angiogenesis, and the role of vascular endothelial growth factor (VEGF) has been extensively proven. Anti-VEGF agents have been shown to be effective in slowing the growth of corneal neovessels. Bevacizumab, an anti-VEGF agent, has been successfully used in the treatment of corneal neovascularization. In this paper, we report a series of patients who underwent intracorneal bevacizumab injections to treat corneal vascularization.
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spelling Intrastromal injection of bevacizumab in patients with corneal neovascularizationCorneal stroma/drug effectsCorneal neovascularization/drug therapyInjections, intraocularAntibodies, monoclonal/dministration & dosageCorneal neovascularization (NV) not only reduces visual acuity, but it also causes loss of the cornea's immune privilege, strongly contributing to a worse prognosis in penetrating keratoplasty. Several mediators participate in corneal angiogenesis, and the role of vascular endothelial growth factor (VEGF) has been extensively proven. Anti-VEGF agents have been shown to be effective in slowing the growth of corneal neovessels. Bevacizumab, an anti-VEGF agent, has been successfully used in the treatment of corneal neovascularization. In this paper, we report a series of patients who underwent intracorneal bevacizumab injections to treat corneal vascularization.Conselho Brasileiro de Oftalmologia2012-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000400012Arquivos Brasileiros de Oftalmologia v.75 n.4 2012reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492012000400012info:eu-repo/semantics/openAccessVieira,Ana Carolina CabreiraHöfling-Lima,Ana LuisaGomes,José Álvaro P.Freitas,Denise deFarah,Michel EidBelfort Jr.,Rubenseng2012-12-18T00:00:00Zoai:scielo:S0004-27492012000400012Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2012-12-18T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Intrastromal injection of bevacizumab in patients with corneal neovascularization
title Intrastromal injection of bevacizumab in patients with corneal neovascularization
spellingShingle Intrastromal injection of bevacizumab in patients with corneal neovascularization
Vieira,Ana Carolina Cabreira
Corneal stroma/drug effects
Corneal neovascularization/drug therapy
Injections, intraocular
Antibodies, monoclonal/dministration & dosage
title_short Intrastromal injection of bevacizumab in patients with corneal neovascularization
title_full Intrastromal injection of bevacizumab in patients with corneal neovascularization
title_fullStr Intrastromal injection of bevacizumab in patients with corneal neovascularization
title_full_unstemmed Intrastromal injection of bevacizumab in patients with corneal neovascularization
title_sort Intrastromal injection of bevacizumab in patients with corneal neovascularization
author Vieira,Ana Carolina Cabreira
author_facet Vieira,Ana Carolina Cabreira
Höfling-Lima,Ana Luisa
Gomes,José Álvaro P.
Freitas,Denise de
Farah,Michel Eid
Belfort Jr.,Rubens
author_role author
author2 Höfling-Lima,Ana Luisa
Gomes,José Álvaro P.
Freitas,Denise de
Farah,Michel Eid
Belfort Jr.,Rubens
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Vieira,Ana Carolina Cabreira
Höfling-Lima,Ana Luisa
Gomes,José Álvaro P.
Freitas,Denise de
Farah,Michel Eid
Belfort Jr.,Rubens
dc.subject.por.fl_str_mv Corneal stroma/drug effects
Corneal neovascularization/drug therapy
Injections, intraocular
Antibodies, monoclonal/dministration & dosage
topic Corneal stroma/drug effects
Corneal neovascularization/drug therapy
Injections, intraocular
Antibodies, monoclonal/dministration & dosage
description Corneal neovascularization (NV) not only reduces visual acuity, but it also causes loss of the cornea's immune privilege, strongly contributing to a worse prognosis in penetrating keratoplasty. Several mediators participate in corneal angiogenesis, and the role of vascular endothelial growth factor (VEGF) has been extensively proven. Anti-VEGF agents have been shown to be effective in slowing the growth of corneal neovessels. Bevacizumab, an anti-VEGF agent, has been successfully used in the treatment of corneal neovascularization. In this paper, we report a series of patients who underwent intracorneal bevacizumab injections to treat corneal vascularization.
publishDate 2012
dc.date.none.fl_str_mv 2012-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000400012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000400012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27492012000400012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.75 n.4 2012
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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