Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole

Detalhes bibliográficos
Autor(a) principal: Gonul,Saban
Data de Publicação: 2015
Outros Autores: Gedik,Sansal, Ozturk,Banu Turgut, Bakbak,Berker, Koktekir,Bengu Ekinci, Okudan,Suleyman, Dagı,Hatice Turk
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400252
Resumo: ABSTRACTPostoperative fungal endophthalmitis is a rare but devastating complication of cataract surgery. Vitrectomy and intravitreal amphotericin B injection as well as administration of systemic antifungal agents have been suggested as optimal treatments for fungal endophthalmitis. However, this therapy may fail to eliminate fungal species resistant to current antifungal agents. The saprophytic fungus Trichosporon asahii is frequently observed as a cause of endogenous endophthalmitis in immunosuppressed patients. We report a case of postoperative endophthalmitis caused by T. asahii, resistant to amphotericin B. To the best of our knowledge, this is the first report of T. asahii endophthalmitis successfully treated with intravitreal and systemic voriconazole, pars plana vitrectomy, and removal of the intraocular lens and entire lens capsule.
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spelling Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazoleEndophthalmitis/etiologyEndophthalmitis/drug therapyPostoperative complicationsPhacoemulsification/complicationTrichosporonPyrimidinesHumansCase reportsABSTRACTPostoperative fungal endophthalmitis is a rare but devastating complication of cataract surgery. Vitrectomy and intravitreal amphotericin B injection as well as administration of systemic antifungal agents have been suggested as optimal treatments for fungal endophthalmitis. However, this therapy may fail to eliminate fungal species resistant to current antifungal agents. The saprophytic fungus Trichosporon asahii is frequently observed as a cause of endogenous endophthalmitis in immunosuppressed patients. We report a case of postoperative endophthalmitis caused by T. asahii, resistant to amphotericin B. To the best of our knowledge, this is the first report of T. asahii endophthalmitis successfully treated with intravitreal and systemic voriconazole, pars plana vitrectomy, and removal of the intraocular lens and entire lens capsule.Conselho Brasileiro de Oftalmologia2015-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400252Arquivos Brasileiros de Oftalmologia v.78 n.4 2015reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20150065info:eu-repo/semantics/openAccessGonul,SabanGedik,SansalOzturk,Banu TurgutBakbak,BerkerKoktekir,Bengu EkinciOkudan,SuleymanDagı,Hatice Turkeng2015-09-09T00:00:00Zoai:scielo:S0004-27492015000400252Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2015-09-09T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
title Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
spellingShingle Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
Gonul,Saban
Endophthalmitis/etiology
Endophthalmitis/drug therapy
Postoperative complications
Phacoemulsification/complication
Trichosporon
Pyrimidines
Humans
Case reports
title_short Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
title_full Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
title_fullStr Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
title_full_unstemmed Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
title_sort Postoperative fungal endophthalmitis caused by Trichosporon asahii treated with voriconazole
author Gonul,Saban
author_facet Gonul,Saban
Gedik,Sansal
Ozturk,Banu Turgut
Bakbak,Berker
Koktekir,Bengu Ekinci
Okudan,Suleyman
Dagı,Hatice Turk
author_role author
author2 Gedik,Sansal
Ozturk,Banu Turgut
Bakbak,Berker
Koktekir,Bengu Ekinci
Okudan,Suleyman
Dagı,Hatice Turk
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gonul,Saban
Gedik,Sansal
Ozturk,Banu Turgut
Bakbak,Berker
Koktekir,Bengu Ekinci
Okudan,Suleyman
Dagı,Hatice Turk
dc.subject.por.fl_str_mv Endophthalmitis/etiology
Endophthalmitis/drug therapy
Postoperative complications
Phacoemulsification/complication
Trichosporon
Pyrimidines
Humans
Case reports
topic Endophthalmitis/etiology
Endophthalmitis/drug therapy
Postoperative complications
Phacoemulsification/complication
Trichosporon
Pyrimidines
Humans
Case reports
description ABSTRACTPostoperative fungal endophthalmitis is a rare but devastating complication of cataract surgery. Vitrectomy and intravitreal amphotericin B injection as well as administration of systemic antifungal agents have been suggested as optimal treatments for fungal endophthalmitis. However, this therapy may fail to eliminate fungal species resistant to current antifungal agents. The saprophytic fungus Trichosporon asahii is frequently observed as a cause of endogenous endophthalmitis in immunosuppressed patients. We report a case of postoperative endophthalmitis caused by T. asahii, resistant to amphotericin B. To the best of our knowledge, this is the first report of T. asahii endophthalmitis successfully treated with intravitreal and systemic voriconazole, pars plana vitrectomy, and removal of the intraocular lens and entire lens capsule.
publishDate 2015
dc.date.none.fl_str_mv 2015-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400252
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400252
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20150065
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.78 n.4 2015
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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