Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?

Detalhes bibliográficos
Autor(a) principal: Oliveira,Lauro Augusto de
Data de Publicação: 2007
Outros Autores: Mallozi,Marcia Carvalho, Sole,Dirceu, Freitas,Denise de, Sousa,Luciene Barbosa de, Mannis,Mark J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020
Resumo: PURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease.
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spelling Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?HypersensitivityConjunctivitis, allergicConjunctiva/immunologySkin testsPURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease.Conselho Brasileiro de Oftalmologia2007-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020Arquivos Brasileiros de Oftalmologia v.70 n.6 2007reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492007000600020info:eu-repo/semantics/openAccessOliveira,Lauro Augusto deMallozi,Marcia CarvalhoSole,DirceuFreitas,Denise deSousa,Luciene Barbosa deMannis,Mark J.eng2008-01-22T00:00:00Zoai:scielo:S0004-27492007000600020Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2008-01-22T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
title Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
spellingShingle Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
Oliveira,Lauro Augusto de
Hypersensitivity
Conjunctivitis, allergic
Conjunctiva/immunology
Skin tests
title_short Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
title_full Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
title_fullStr Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
title_full_unstemmed Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
title_sort Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
author Oliveira,Lauro Augusto de
author_facet Oliveira,Lauro Augusto de
Mallozi,Marcia Carvalho
Sole,Dirceu
Freitas,Denise de
Sousa,Luciene Barbosa de
Mannis,Mark J.
author_role author
author2 Mallozi,Marcia Carvalho
Sole,Dirceu
Freitas,Denise de
Sousa,Luciene Barbosa de
Mannis,Mark J.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira,Lauro Augusto de
Mallozi,Marcia Carvalho
Sole,Dirceu
Freitas,Denise de
Sousa,Luciene Barbosa de
Mannis,Mark J.
dc.subject.por.fl_str_mv Hypersensitivity
Conjunctivitis, allergic
Conjunctiva/immunology
Skin tests
topic Hypersensitivity
Conjunctivitis, allergic
Conjunctiva/immunology
Skin tests
description PURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease.
publishDate 2007
dc.date.none.fl_str_mv 2007-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27492007000600020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.70 n.6 2007
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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