Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos brasileiros de oftalmologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020 |
Resumo: | PURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease. |
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Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis?HypersensitivityConjunctivitis, allergicConjunctiva/immunologySkin testsPURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease.Conselho Brasileiro de Oftalmologia2007-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020Arquivos Brasileiros de Oftalmologia v.70 n.6 2007reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492007000600020info:eu-repo/semantics/openAccessOliveira,Lauro Augusto deMallozi,Marcia CarvalhoSole,DirceuFreitas,Denise deSousa,Luciene Barbosa deMannis,Mark J.eng2008-01-22T00:00:00Zoai:scielo:S0004-27492007000600020Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2008-01-22T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false |
dc.title.none.fl_str_mv |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
title |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
spellingShingle |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? Oliveira,Lauro Augusto de Hypersensitivity Conjunctivitis, allergic Conjunctiva/immunology Skin tests |
title_short |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
title_full |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
title_fullStr |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
title_full_unstemmed |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
title_sort |
Are cutaneous hypersensitivity tests to inhalant allergens a severity marker for vernal keratoconjunctivitis? |
author |
Oliveira,Lauro Augusto de |
author_facet |
Oliveira,Lauro Augusto de Mallozi,Marcia Carvalho Sole,Dirceu Freitas,Denise de Sousa,Luciene Barbosa de Mannis,Mark J. |
author_role |
author |
author2 |
Mallozi,Marcia Carvalho Sole,Dirceu Freitas,Denise de Sousa,Luciene Barbosa de Mannis,Mark J. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Lauro Augusto de Mallozi,Marcia Carvalho Sole,Dirceu Freitas,Denise de Sousa,Luciene Barbosa de Mannis,Mark J. |
dc.subject.por.fl_str_mv |
Hypersensitivity Conjunctivitis, allergic Conjunctiva/immunology Skin tests |
topic |
Hypersensitivity Conjunctivitis, allergic Conjunctiva/immunology Skin tests |
description |
PURPOSE: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. METHODS: Twenty patients with vernal keratoconjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated, and a score ranging from 0 to 20 was applied based on signs and symptoms on ophthalmic examination. All subjects underwent a skin prick test against standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather. RESULTS: Seventy-five per cent of patients were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%). There was a poor correlation between the clinical score and sensitivity to allergens (r= - 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract (r = - 0.510; p=0.024). CONCLUSIONS: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinical findings in patients with vernal keratoconjuntivitis. We concluded that skin response to inhalant allergens is not a useful test to identify clinical severity and chronicity of inflammatory process in this disease. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000600020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-27492007000600020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Conselho Brasileiro de Oftalmologia |
publisher.none.fl_str_mv |
Conselho Brasileiro de Oftalmologia |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Oftalmologia v.70 n.6 2007 reponame:Arquivos brasileiros de oftalmologia (Online) instname:Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO |
instname_str |
Conselho Brasileiro de Oftalmologia (CBO) |
instacron_str |
CBO |
institution |
CBO |
reponame_str |
Arquivos brasileiros de oftalmologia (Online) |
collection |
Arquivos brasileiros de oftalmologia (Online) |
repository.name.fl_str_mv |
Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO) |
repository.mail.fl_str_mv |
aboonline@cbo.com.br||abo@cbo.com.br |
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1754209024672268288 |