Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis

Detalhes bibliográficos
Autor(a) principal: Gazim,Caio Cézar
Data de Publicação: 2023
Outros Autores: Borba,Angelo Antonio de, Castro,Grace Kelly Pelicioni de, Simioni,Juliana, Gehlen,Marcelo Luiz, Ramos Júnior,Odery, Skare,Thelma Larocca
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492023000100033
Resumo: ABSTRACT Purpose: This study measured fecal calprotectin levels in a series of patients with anterior uveitis in order to determine whether anterior uveitis patients with associated spondyloarthritis have higher levels of fecal calprotectin than patients with anterior uveitis of other etiologies. A third group of patients with spondyloarthritis without uveitis was also evaluated to understand the role of acute anterior uveitis in increasing fecal calprotectin. Methods: In this cross-sectional study, 28 patients were divided into three groups: (a) Group 1, spondyloarthritis and uveitis (n=9); (b) Group 2, spondyloarthritis without uveitis (n=10); and (c) Group 3, uveitis without spondyloarthritis (n=9). The levels of fecal calprotectin were determined. Results: Groups 1 and 2 showed higher median fecal calprotectin levels (101.0 and 93.0 µg/g, respectively) compared with Group 3 (9.0 µg/g) (p=0.02). However, no relationship between fecal calprotectin levels and the presence of uveitis with spondyloarthritis could be demonstrated. Conclusion: Patients with spondyloarthritis with or without acute anterior uveitis have significantly elevated levels of fecal calprotectin. This test may be useful for differentiating spondyloarthrit-associated uveitis from uveitis of other etiologies.
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spelling Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritisCalprotectinUveitisSpondyloarthritisInflammatory bowel diseasesBiomarkersABSTRACT Purpose: This study measured fecal calprotectin levels in a series of patients with anterior uveitis in order to determine whether anterior uveitis patients with associated spondyloarthritis have higher levels of fecal calprotectin than patients with anterior uveitis of other etiologies. A third group of patients with spondyloarthritis without uveitis was also evaluated to understand the role of acute anterior uveitis in increasing fecal calprotectin. Methods: In this cross-sectional study, 28 patients were divided into three groups: (a) Group 1, spondyloarthritis and uveitis (n=9); (b) Group 2, spondyloarthritis without uveitis (n=10); and (c) Group 3, uveitis without spondyloarthritis (n=9). The levels of fecal calprotectin were determined. Results: Groups 1 and 2 showed higher median fecal calprotectin levels (101.0 and 93.0 µg/g, respectively) compared with Group 3 (9.0 µg/g) (p=0.02). However, no relationship between fecal calprotectin levels and the presence of uveitis with spondyloarthritis could be demonstrated. Conclusion: Patients with spondyloarthritis with or without acute anterior uveitis have significantly elevated levels of fecal calprotectin. This test may be useful for differentiating spondyloarthrit-associated uveitis from uveitis of other etiologies.Conselho Brasileiro de Oftalmologia2023-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492023000100033Arquivos Brasileiros de Oftalmologia v.86 n.1 2023reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20230008info:eu-repo/semantics/openAccessGazim,Caio CézarBorba,Angelo Antonio deCastro,Grace Kelly Pelicioni deSimioni,JulianaGehlen,Marcelo LuizRamos Júnior,OderySkare,Thelma Laroccaeng2022-11-29T00:00:00Zoai:scielo:S0004-27492023000100033Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2022-11-29T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
title Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
spellingShingle Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
Gazim,Caio Cézar
Calprotectin
Uveitis
Spondyloarthritis
Inflammatory bowel diseases
Biomarkers
title_short Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
title_full Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
title_fullStr Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
title_full_unstemmed Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
title_sort Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis
author Gazim,Caio Cézar
author_facet Gazim,Caio Cézar
Borba,Angelo Antonio de
Castro,Grace Kelly Pelicioni de
Simioni,Juliana
Gehlen,Marcelo Luiz
Ramos Júnior,Odery
Skare,Thelma Larocca
author_role author
author2 Borba,Angelo Antonio de
Castro,Grace Kelly Pelicioni de
Simioni,Juliana
Gehlen,Marcelo Luiz
Ramos Júnior,Odery
Skare,Thelma Larocca
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gazim,Caio Cézar
Borba,Angelo Antonio de
Castro,Grace Kelly Pelicioni de
Simioni,Juliana
Gehlen,Marcelo Luiz
Ramos Júnior,Odery
Skare,Thelma Larocca
dc.subject.por.fl_str_mv Calprotectin
Uveitis
Spondyloarthritis
Inflammatory bowel diseases
Biomarkers
topic Calprotectin
Uveitis
Spondyloarthritis
Inflammatory bowel diseases
Biomarkers
description ABSTRACT Purpose: This study measured fecal calprotectin levels in a series of patients with anterior uveitis in order to determine whether anterior uveitis patients with associated spondyloarthritis have higher levels of fecal calprotectin than patients with anterior uveitis of other etiologies. A third group of patients with spondyloarthritis without uveitis was also evaluated to understand the role of acute anterior uveitis in increasing fecal calprotectin. Methods: In this cross-sectional study, 28 patients were divided into three groups: (a) Group 1, spondyloarthritis and uveitis (n=9); (b) Group 2, spondyloarthritis without uveitis (n=10); and (c) Group 3, uveitis without spondyloarthritis (n=9). The levels of fecal calprotectin were determined. Results: Groups 1 and 2 showed higher median fecal calprotectin levels (101.0 and 93.0 µg/g, respectively) compared with Group 3 (9.0 µg/g) (p=0.02). However, no relationship between fecal calprotectin levels and the presence of uveitis with spondyloarthritis could be demonstrated. Conclusion: Patients with spondyloarthritis with or without acute anterior uveitis have significantly elevated levels of fecal calprotectin. This test may be useful for differentiating spondyloarthrit-associated uveitis from uveitis of other etiologies.
publishDate 2023
dc.date.none.fl_str_mv 2023-02-01
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dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20230008
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dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.86 n.1 2023
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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