Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy

Detalhes bibliográficos
Autor(a) principal: Viana,Karlos Ítalo
Data de Publicação: 2017
Outros Autores: Messias,André, Siqueira,Rubens Camargo, Rodrigues,Murilo W., Jorge,Rodrigo
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492017000200118
Resumo: ABSTRACT We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive optics (AO) camera (RTX1, Imagine Eyes) for photoreceptor density analysis. Functional tests included full-field ERG (ERG) and multifocal electroretinography (mfERG) (Diagnosys, LLC) and microperimetry with scanning laser ophthalmoscope (SLO) fixation controlled (MAIA, CenterVUE). OCT revealed a line of discontinuity corresponding to cone outer-segment photoreceptors associated with a loss of cone density, highlighted by a dark blue spot on the AO co ne-density map on the fovea in both eyes. Loss of central sensitivity was revealed using microperimetry; ERG was within the normal range, although the mfERG showed a reduced central response amplitude.
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spelling Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophyMacular degeneration/diagnosisPhotoreceptor cellsVisual field testsElectroretinographyTomography, optical coherenceABSTRACT We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive optics (AO) camera (RTX1, Imagine Eyes) for photoreceptor density analysis. Functional tests included full-field ERG (ERG) and multifocal electroretinography (mfERG) (Diagnosys, LLC) and microperimetry with scanning laser ophthalmoscope (SLO) fixation controlled (MAIA, CenterVUE). OCT revealed a line of discontinuity corresponding to cone outer-segment photoreceptors associated with a loss of cone density, highlighted by a dark blue spot on the AO co ne-density map on the fovea in both eyes. Loss of central sensitivity was revealed using microperimetry; ERG was within the normal range, although the mfERG showed a reduced central response amplitude.Conselho Brasileiro de Oftalmologia2017-04-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492017000200118Arquivos Brasileiros de Oftalmologia v.80 n.2 2017reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20170028info:eu-repo/semantics/openAccessViana,Karlos ÍtaloMessias,AndréSiqueira,Rubens CamargoRodrigues,Murilo W.Jorge,Rodrigoeng2017-06-01T00:00:00Zoai:scielo:S0004-27492017000200118Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2017-06-01T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
title Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
spellingShingle Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
Viana,Karlos Ítalo
Macular degeneration/diagnosis
Photoreceptor cells
Visual field tests
Electroretinography
Tomography, optical coherence
title_short Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
title_full Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
title_fullStr Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
title_full_unstemmed Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
title_sort Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy
author Viana,Karlos Ítalo
author_facet Viana,Karlos Ítalo
Messias,André
Siqueira,Rubens Camargo
Rodrigues,Murilo W.
Jorge,Rodrigo
author_role author
author2 Messias,André
Siqueira,Rubens Camargo
Rodrigues,Murilo W.
Jorge,Rodrigo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Viana,Karlos Ítalo
Messias,André
Siqueira,Rubens Camargo
Rodrigues,Murilo W.
Jorge,Rodrigo
dc.subject.por.fl_str_mv Macular degeneration/diagnosis
Photoreceptor cells
Visual field tests
Electroretinography
Tomography, optical coherence
topic Macular degeneration/diagnosis
Photoreceptor cells
Visual field tests
Electroretinography
Tomography, optical coherence
description ABSTRACT We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive optics (AO) camera (RTX1, Imagine Eyes) for photoreceptor density analysis. Functional tests included full-field ERG (ERG) and multifocal electroretinography (mfERG) (Diagnosys, LLC) and microperimetry with scanning laser ophthalmoscope (SLO) fixation controlled (MAIA, CenterVUE). OCT revealed a line of discontinuity corresponding to cone outer-segment photoreceptors associated with a loss of cone density, highlighted by a dark blue spot on the AO co ne-density map on the fovea in both eyes. Loss of central sensitivity was revealed using microperimetry; ERG was within the normal range, although the mfERG showed a reduced central response amplitude.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492017000200118
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492017000200118
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20170028
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.80 n.2 2017
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
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