Antiangiogenic drugs and advanced proliferative diabetic retinopathy

Detalhes bibliográficos
Autor(a) principal: Ribeiro,Jefferson Augusto Santana
Data de Publicação: 2011
Outros Autores: Messias,André, Jorge,Rodrigo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492011000200017
Resumo: Advanced diabetic retinopathy with tractional retinal detachment or persistent vitreous hemorrhage often requires surgical treatment with pars plana vitrectomy. Despite advances in vitrectomy, surgery for complications of diabetic retinopathy can be a challenge and may be impaired by intense fibrovascular proliferation. Antiangiogenic drugs have been used for the treatment of diabetic retinopathy because of their inhibitory action on vascular endothelial growth factor. In this review, we discuss aspects related to the adjuvant use of these drugs in vitrectomy for complications of diabetic retinopathy. Bevacizumab shows beneficial effects regarding the surgical technique facilitation, but its long-term benefit still needs to be studied.
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spelling Antiangiogenic drugs and advanced proliferative diabetic retinopathyAnti-angiogenic drugsVitrectomyDiabetic retinopathyRetinal detachmentVitreous hemorrhageAdvanced diabetic retinopathy with tractional retinal detachment or persistent vitreous hemorrhage often requires surgical treatment with pars plana vitrectomy. Despite advances in vitrectomy, surgery for complications of diabetic retinopathy can be a challenge and may be impaired by intense fibrovascular proliferation. Antiangiogenic drugs have been used for the treatment of diabetic retinopathy because of their inhibitory action on vascular endothelial growth factor. In this review, we discuss aspects related to the adjuvant use of these drugs in vitrectomy for complications of diabetic retinopathy. Bevacizumab shows beneficial effects regarding the surgical technique facilitation, but its long-term benefit still needs to be studied.Conselho Brasileiro de Oftalmologia2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492011000200017Arquivos Brasileiros de Oftalmologia v.74 n.2 2011reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492011000200017info:eu-repo/semantics/openAccessRibeiro,Jefferson Augusto SantanaMessias,AndréJorge,Rodrigoeng2011-07-11T00:00:00Zoai:scielo:S0004-27492011000200017Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2011-07-11T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Antiangiogenic drugs and advanced proliferative diabetic retinopathy
title Antiangiogenic drugs and advanced proliferative diabetic retinopathy
spellingShingle Antiangiogenic drugs and advanced proliferative diabetic retinopathy
Ribeiro,Jefferson Augusto Santana
Anti-angiogenic drugs
Vitrectomy
Diabetic retinopathy
Retinal detachment
Vitreous hemorrhage
title_short Antiangiogenic drugs and advanced proliferative diabetic retinopathy
title_full Antiangiogenic drugs and advanced proliferative diabetic retinopathy
title_fullStr Antiangiogenic drugs and advanced proliferative diabetic retinopathy
title_full_unstemmed Antiangiogenic drugs and advanced proliferative diabetic retinopathy
title_sort Antiangiogenic drugs and advanced proliferative diabetic retinopathy
author Ribeiro,Jefferson Augusto Santana
author_facet Ribeiro,Jefferson Augusto Santana
Messias,André
Jorge,Rodrigo
author_role author
author2 Messias,André
Jorge,Rodrigo
author2_role author
author
dc.contributor.author.fl_str_mv Ribeiro,Jefferson Augusto Santana
Messias,André
Jorge,Rodrigo
dc.subject.por.fl_str_mv Anti-angiogenic drugs
Vitrectomy
Diabetic retinopathy
Retinal detachment
Vitreous hemorrhage
topic Anti-angiogenic drugs
Vitrectomy
Diabetic retinopathy
Retinal detachment
Vitreous hemorrhage
description Advanced diabetic retinopathy with tractional retinal detachment or persistent vitreous hemorrhage often requires surgical treatment with pars plana vitrectomy. Despite advances in vitrectomy, surgery for complications of diabetic retinopathy can be a challenge and may be impaired by intense fibrovascular proliferation. Antiangiogenic drugs have been used for the treatment of diabetic retinopathy because of their inhibitory action on vascular endothelial growth factor. In this review, we discuss aspects related to the adjuvant use of these drugs in vitrectomy for complications of diabetic retinopathy. Bevacizumab shows beneficial effects regarding the surgical technique facilitation, but its long-term benefit still needs to be studied.
publishDate 2011
dc.date.none.fl_str_mv 2011-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492011000200017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492011000200017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27492011000200017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.74 n.2 2011
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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