Hypertension and its correlation with renal lesions in dogs with leishmaniosis
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Parasitologia Veterinária (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612015000100006 |
Resumo: | To evaluate the prevalence of hypertension and its correlation with the severity of renal injury and proteinuria in dogs with leishmaniosis, sixty-six dogs were divided into two groups. Group 1 (G1) was composed of 54 dogs included in stage 1 of chronic kidney disease (CKD), and group 2 (G2) of twelve dogs in stages 2 and 3 of CKD. Prevalence of hypertension was 28.8%, comprising 22.2% of the dogs from G1 and 58.3% from G2 (P=0.011). The mean arterial blood pressure (BP) of dogs from G1 (135.7 ± 20.5) was lower than from G2 (170.0 ± 26.3) (P <0.001). Urine protein-creatinine ratio (UP/C) revealed values above 0.5 in 75.7% of the dogs, with 34% presenting hypertension. All dogs with hypertension had histopathological and laboratory evidence of glomerular disease. Although there was no statistically significant correlation between elevated BP and the severity of glomerular lesions (P=0.408), there was a statistically significant correlation between elevated BP and increased UP/C in the studied population (P=0.002). Thus, dogs with leishmaniosis and renal disease must be screened for the presence of hypertension so that treatment may be instituted as early as possible, in countries where treatment is allowed, to prevent the progression of renal damage. |
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Hypertension and its correlation with renal lesions in dogs with leishmaniosisHistopathologykidneyLeishmania infantum chagasisystolic blood pressureTo evaluate the prevalence of hypertension and its correlation with the severity of renal injury and proteinuria in dogs with leishmaniosis, sixty-six dogs were divided into two groups. Group 1 (G1) was composed of 54 dogs included in stage 1 of chronic kidney disease (CKD), and group 2 (G2) of twelve dogs in stages 2 and 3 of CKD. Prevalence of hypertension was 28.8%, comprising 22.2% of the dogs from G1 and 58.3% from G2 (P=0.011). The mean arterial blood pressure (BP) of dogs from G1 (135.7 ± 20.5) was lower than from G2 (170.0 ± 26.3) (P <0.001). Urine protein-creatinine ratio (UP/C) revealed values above 0.5 in 75.7% of the dogs, with 34% presenting hypertension. All dogs with hypertension had histopathological and laboratory evidence of glomerular disease. Although there was no statistically significant correlation between elevated BP and the severity of glomerular lesions (P=0.408), there was a statistically significant correlation between elevated BP and increased UP/C in the studied population (P=0.002). Thus, dogs with leishmaniosis and renal disease must be screened for the presence of hypertension so that treatment may be instituted as early as possible, in countries where treatment is allowed, to prevent the progression of renal damage.Colégio Brasileiro de Parasitologia Veterinária2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612015000100006Revista Brasileira de Parasitologia Veterinária v.24 n.1 2015reponame:Revista Brasileira de Parasitologia Veterinária (Online)instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV)instacron:CBPV10.1590/S1984-29612015007info:eu-repo/semantics/openAccessBraga,Eveline TozziLeite,João Henrique Artero de CarvalhoRosa,Fernando AzadinhoTivelli,PatríciaAraújo,Amanda MarianoAlmeida,Breno Fernando Martins deFerrari,Heitor FlávioCiarlini,Paulo CésarMachado,Gisele FabrinoMarcondes,Maryeng2016-01-15T00:00:00Zoai:scielo:S1984-29612015000100006Revistahttp://www.scielo.br/scielo.php?script=sci_serial&lng=pt&pid=1984-2961https://old.scielo.br/oai/scielo-oai.php||zacariascbpv@fcav.unesp.br1984-29610103-846Xopendoar:2016-01-15T00:00Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV)false |
dc.title.none.fl_str_mv |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
title |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
spellingShingle |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis Braga,Eveline Tozzi Histopathology kidney Leishmania infantum chagasi systolic blood pressure |
title_short |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
title_full |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
title_fullStr |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
title_full_unstemmed |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
title_sort |
Hypertension and its correlation with renal lesions in dogs with leishmaniosis |
author |
Braga,Eveline Tozzi |
author_facet |
Braga,Eveline Tozzi Leite,João Henrique Artero de Carvalho Rosa,Fernando Azadinho Tivelli,Patrícia Araújo,Amanda Mariano Almeida,Breno Fernando Martins de Ferrari,Heitor Flávio Ciarlini,Paulo César Machado,Gisele Fabrino Marcondes,Mary |
author_role |
author |
author2 |
Leite,João Henrique Artero de Carvalho Rosa,Fernando Azadinho Tivelli,Patrícia Araújo,Amanda Mariano Almeida,Breno Fernando Martins de Ferrari,Heitor Flávio Ciarlini,Paulo César Machado,Gisele Fabrino Marcondes,Mary |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Braga,Eveline Tozzi Leite,João Henrique Artero de Carvalho Rosa,Fernando Azadinho Tivelli,Patrícia Araújo,Amanda Mariano Almeida,Breno Fernando Martins de Ferrari,Heitor Flávio Ciarlini,Paulo César Machado,Gisele Fabrino Marcondes,Mary |
dc.subject.por.fl_str_mv |
Histopathology kidney Leishmania infantum chagasi systolic blood pressure |
topic |
Histopathology kidney Leishmania infantum chagasi systolic blood pressure |
description |
To evaluate the prevalence of hypertension and its correlation with the severity of renal injury and proteinuria in dogs with leishmaniosis, sixty-six dogs were divided into two groups. Group 1 (G1) was composed of 54 dogs included in stage 1 of chronic kidney disease (CKD), and group 2 (G2) of twelve dogs in stages 2 and 3 of CKD. Prevalence of hypertension was 28.8%, comprising 22.2% of the dogs from G1 and 58.3% from G2 (P=0.011). The mean arterial blood pressure (BP) of dogs from G1 (135.7 ± 20.5) was lower than from G2 (170.0 ± 26.3) (P <0.001). Urine protein-creatinine ratio (UP/C) revealed values above 0.5 in 75.7% of the dogs, with 34% presenting hypertension. All dogs with hypertension had histopathological and laboratory evidence of glomerular disease. Although there was no statistically significant correlation between elevated BP and the severity of glomerular lesions (P=0.408), there was a statistically significant correlation between elevated BP and increased UP/C in the studied population (P=0.002). Thus, dogs with leishmaniosis and renal disease must be screened for the presence of hypertension so that treatment may be instituted as early as possible, in countries where treatment is allowed, to prevent the progression of renal damage. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612015000100006 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612015000100006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1984-29612015007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Parasitologia Veterinária |
publisher.none.fl_str_mv |
Colégio Brasileiro de Parasitologia Veterinária |
dc.source.none.fl_str_mv |
Revista Brasileira de Parasitologia Veterinária v.24 n.1 2015 reponame:Revista Brasileira de Parasitologia Veterinária (Online) instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV) instacron:CBPV |
instname_str |
Colégio Brasileiro de Parasitologia Veterinária (CBPV) |
instacron_str |
CBPV |
institution |
CBPV |
reponame_str |
Revista Brasileira de Parasitologia Veterinária (Online) |
collection |
Revista Brasileira de Parasitologia Veterinária (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV) |
repository.mail.fl_str_mv |
||zacariascbpv@fcav.unesp.br |
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1754208915334103040 |