Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000400216 |
Resumo: | Abstract Objective: To assess the practical aspects of the use of various gadolinium-based contrast agents (GBCAs) by radiologists. Materials and Methods: Ten experienced radiologists from different regions of Brazil participated in a Delphi panel querying their use of various GBCAs, including linear and macrocyclic classes (1.0 and 0.5 M), in terms of the choice of agent, volume and dosage of the agents, and associated safety concerns. Results: The response rate was 100% for all questions. GBCAs are safe in terms of acute adverse reactions, and nephrogenic systemic fibrosis is rare. The deposition of gadolinium in the brain and other tissues is a concern among the experts. Macrocyclic agents are preferable to linear agents; an injection volume below 0.1 mL/kg of a 1.0 M agent could result in good-quality images with additional long-term safety, but there is no published evidence to support this recommendation. The majority of experts preferred not to administer GBCAs to pregnant patients. Conclusion: When choosing a GBCA, it is important to consider the characteristics of the gadolinium deposition in patient tissues and minimize potential risks. Furthermore, medical education programs are needed to increase the awareness of the potential risks of gadolinium deposition and thus avoid instances of overexposure to the contrast agent. |
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Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel studyContrast mediaGadoliniumMagnetic resonance imagingGadolinium-based contrast agentsSafetyAbstract Objective: To assess the practical aspects of the use of various gadolinium-based contrast agents (GBCAs) by radiologists. Materials and Methods: Ten experienced radiologists from different regions of Brazil participated in a Delphi panel querying their use of various GBCAs, including linear and macrocyclic classes (1.0 and 0.5 M), in terms of the choice of agent, volume and dosage of the agents, and associated safety concerns. Results: The response rate was 100% for all questions. GBCAs are safe in terms of acute adverse reactions, and nephrogenic systemic fibrosis is rare. The deposition of gadolinium in the brain and other tissues is a concern among the experts. Macrocyclic agents are preferable to linear agents; an injection volume below 0.1 mL/kg of a 1.0 M agent could result in good-quality images with additional long-term safety, but there is no published evidence to support this recommendation. The majority of experts preferred not to administer GBCAs to pregnant patients. Conclusion: When choosing a GBCA, it is important to consider the characteristics of the gadolinium deposition in patient tissues and minimize potential risks. Furthermore, medical education programs are needed to increase the awareness of the potential risks of gadolinium deposition and thus avoid instances of overexposure to the contrast agent.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2020-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000400216Radiologia Brasileira v.53 n.4 2020reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2019.0074info:eu-repo/semantics/openAccessBaroni,Ronaldo HuebBauab Jr.,TufikBittencourt,Leonardo KayatD’Ippolito,GiuseppeGoldman,Suzan MenasceHohgraefe Neto,GuilhermeManzella,AdonisRocha,Antonio JoséSonoda,Luis AugustoTakeda,Fabio Seichieng2020-08-17T00:00:00Zoai:scielo:S0100-39842020000400216Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2020-08-17T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
title |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
spellingShingle |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study Baroni,Ronaldo Hueb Contrast media Gadolinium Magnetic resonance imaging Gadolinium-based contrast agents Safety |
title_short |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
title_full |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
title_fullStr |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
title_full_unstemmed |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
title_sort |
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study |
author |
Baroni,Ronaldo Hueb |
author_facet |
Baroni,Ronaldo Hueb Bauab Jr.,Tufik Bittencourt,Leonardo Kayat D’Ippolito,Giuseppe Goldman,Suzan Menasce Hohgraefe Neto,Guilherme Manzella,Adonis Rocha,Antonio José Sonoda,Luis Augusto Takeda,Fabio Seichi |
author_role |
author |
author2 |
Bauab Jr.,Tufik Bittencourt,Leonardo Kayat D’Ippolito,Giuseppe Goldman,Suzan Menasce Hohgraefe Neto,Guilherme Manzella,Adonis Rocha,Antonio José Sonoda,Luis Augusto Takeda,Fabio Seichi |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Baroni,Ronaldo Hueb Bauab Jr.,Tufik Bittencourt,Leonardo Kayat D’Ippolito,Giuseppe Goldman,Suzan Menasce Hohgraefe Neto,Guilherme Manzella,Adonis Rocha,Antonio José Sonoda,Luis Augusto Takeda,Fabio Seichi |
dc.subject.por.fl_str_mv |
Contrast media Gadolinium Magnetic resonance imaging Gadolinium-based contrast agents Safety |
topic |
Contrast media Gadolinium Magnetic resonance imaging Gadolinium-based contrast agents Safety |
description |
Abstract Objective: To assess the practical aspects of the use of various gadolinium-based contrast agents (GBCAs) by radiologists. Materials and Methods: Ten experienced radiologists from different regions of Brazil participated in a Delphi panel querying their use of various GBCAs, including linear and macrocyclic classes (1.0 and 0.5 M), in terms of the choice of agent, volume and dosage of the agents, and associated safety concerns. Results: The response rate was 100% for all questions. GBCAs are safe in terms of acute adverse reactions, and nephrogenic systemic fibrosis is rare. The deposition of gadolinium in the brain and other tissues is a concern among the experts. Macrocyclic agents are preferable to linear agents; an injection volume below 0.1 mL/kg of a 1.0 M agent could result in good-quality images with additional long-term safety, but there is no published evidence to support this recommendation. The majority of experts preferred not to administer GBCAs to pregnant patients. Conclusion: When choosing a GBCA, it is important to consider the characteristics of the gadolinium deposition in patient tissues and minimize potential risks. Furthermore, medical education programs are needed to increase the awareness of the potential risks of gadolinium deposition and thus avoid instances of overexposure to the contrast agent. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000400216 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000400216 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0100-3984.2019.0074 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.53 n.4 2020 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208940729565184 |