One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842018000300151 |
Resumo: | Abstract Objective: To show the initial (first-year) experience with 68Ga-PSMA PET/CT at a clinic in Brazil. Materials and Methods: Over a one-year period, 96 examinations with 68Ga-PSMA PET/CT (85 related to prostate cancer and 11 related to kidney cancer) were performed in 90 patients. Results: In the prostate and kidney cancer patients alike, the main clinical indication for 68Ga-PSMA PET/CT was suspicion of recurrence during follow-up (in 65.8% and 63.0% of the cases, respectively). Among the prostate cancer patients, 38.5% of those with a prostate specific antigen (PSA) < 0.5 ng/mL tested positive for recurrence on 68Ga-PSMA PET/CT, compared with 71.0% of those with a PSA of 0.5-0.99, 85.7% of those with a PSA of 1.0-1.99, and 92.6% of those with a PSA > 1.99. Conclusion: Although 68Ga-PSMA PET/CT is a technique that has only recently been applied in clinical settings, despite its high cost, 68Ga-PSMA PET/CT shows great promise as a tool in the clinical management of patients with kidney and prostate cancer, especially in those with prostate cancer whose PSA levels are elevated even after treatment. |
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One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancerProstate cancerKidney cancerPET/CT68Ga-PSMAAbstract Objective: To show the initial (first-year) experience with 68Ga-PSMA PET/CT at a clinic in Brazil. Materials and Methods: Over a one-year period, 96 examinations with 68Ga-PSMA PET/CT (85 related to prostate cancer and 11 related to kidney cancer) were performed in 90 patients. Results: In the prostate and kidney cancer patients alike, the main clinical indication for 68Ga-PSMA PET/CT was suspicion of recurrence during follow-up (in 65.8% and 63.0% of the cases, respectively). Among the prostate cancer patients, 38.5% of those with a prostate specific antigen (PSA) < 0.5 ng/mL tested positive for recurrence on 68Ga-PSMA PET/CT, compared with 71.0% of those with a PSA of 0.5-0.99, 85.7% of those with a PSA of 1.0-1.99, and 92.6% of those with a PSA > 1.99. Conclusion: Although 68Ga-PSMA PET/CT is a technique that has only recently been applied in clinical settings, despite its high cost, 68Ga-PSMA PET/CT shows great promise as a tool in the clinical management of patients with kidney and prostate cancer, especially in those with prostate cancer whose PSA levels are elevated even after treatment.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2018-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842018000300151Radiologia Brasileira v.51 n.3 2018reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2017.0008info:eu-repo/semantics/openAccessPrado Júnior,Luciano MonteiroMarino,Fiorella MenegattiBarra,RenatoPrado,Leonardo Fonseca Monteiro doBarra Sobrinho,Alaoreng2018-07-10T00:00:00Zoai:scielo:S0100-39842018000300151Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2018-07-10T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
title |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
spellingShingle |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer Prado Júnior,Luciano Monteiro Prostate cancer Kidney cancer PET/CT 68Ga-PSMA |
title_short |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
title_full |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
title_fullStr |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
title_full_unstemmed |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
title_sort |
One-year experience with 68Ga-PSMA PET/CT: applications and results in biochemical recurrence of prostate cancer |
author |
Prado Júnior,Luciano Monteiro |
author_facet |
Prado Júnior,Luciano Monteiro Marino,Fiorella Menegatti Barra,Renato Prado,Leonardo Fonseca Monteiro do Barra Sobrinho,Alaor |
author_role |
author |
author2 |
Marino,Fiorella Menegatti Barra,Renato Prado,Leonardo Fonseca Monteiro do Barra Sobrinho,Alaor |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Prado Júnior,Luciano Monteiro Marino,Fiorella Menegatti Barra,Renato Prado,Leonardo Fonseca Monteiro do Barra Sobrinho,Alaor |
dc.subject.por.fl_str_mv |
Prostate cancer Kidney cancer PET/CT 68Ga-PSMA |
topic |
Prostate cancer Kidney cancer PET/CT 68Ga-PSMA |
description |
Abstract Objective: To show the initial (first-year) experience with 68Ga-PSMA PET/CT at a clinic in Brazil. Materials and Methods: Over a one-year period, 96 examinations with 68Ga-PSMA PET/CT (85 related to prostate cancer and 11 related to kidney cancer) were performed in 90 patients. Results: In the prostate and kidney cancer patients alike, the main clinical indication for 68Ga-PSMA PET/CT was suspicion of recurrence during follow-up (in 65.8% and 63.0% of the cases, respectively). Among the prostate cancer patients, 38.5% of those with a prostate specific antigen (PSA) < 0.5 ng/mL tested positive for recurrence on 68Ga-PSMA PET/CT, compared with 71.0% of those with a PSA of 0.5-0.99, 85.7% of those with a PSA of 1.0-1.99, and 92.6% of those with a PSA > 1.99. Conclusion: Although 68Ga-PSMA PET/CT is a technique that has only recently been applied in clinical settings, despite its high cost, 68Ga-PSMA PET/CT shows great promise as a tool in the clinical management of patients with kidney and prostate cancer, especially in those with prostate cancer whose PSA levels are elevated even after treatment. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842018000300151 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842018000300151 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0100-3984.2017.0008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.51 n.3 2018 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208939800526848 |