Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Radiologia Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000500284 |
Resumo: | Objective To suggest a national value for the diagnostic reference level (DRL) in terms of activity in MBq.kg–1, for nuclear medicine procedures with fluorodeoxyglucose (18F-FDG) in whole body positron emission tomography (PET) scans of adult patients. Materials and Methods A survey on values of 18F-FDG activity administered in Brazilian clinics was undertaken by means of a questionnaire including questions about number and manufacturer of the installed equipment, model and detector type. The suggested DRL value was based on the calculation of the third quartile of the activity values distribution reported by the clinics. Results Among the surveyed Brazilian clinics, 58% responded completely or partially the questionnaire; and the results demonstrated variation of up to 100% in the reported radiopharmaceutical activity. The suggested DRL for 18F-FDG/PET activity was 5.54 MBq.kg–1 (0.149 mCi.kg–1). Conclusion The present study has demonstrated the lack of standardization in administered radiopharmaceutical activities for PET procedures in Brazil, corroborating the necessity of an official DRL value to be adopted in the country. The suggested DLR value demonstrates that there is room for optimization of the procedures and 18F-FDG/PET activities administered in Brazilian clinics to reduce the doses delivered to patients. It is important to highlight that this value should be continually revised and optimized at least every five years. |
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Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in BrazilNuclear medicinePositron emission tomographyDiagnostic reference levelRadiopharmaceutical 18F-FDG Objective To suggest a national value for the diagnostic reference level (DRL) in terms of activity in MBq.kg–1, for nuclear medicine procedures with fluorodeoxyglucose (18F-FDG) in whole body positron emission tomography (PET) scans of adult patients. Materials and Methods A survey on values of 18F-FDG activity administered in Brazilian clinics was undertaken by means of a questionnaire including questions about number and manufacturer of the installed equipment, model and detector type. The suggested DRL value was based on the calculation of the third quartile of the activity values distribution reported by the clinics. Results Among the surveyed Brazilian clinics, 58% responded completely or partially the questionnaire; and the results demonstrated variation of up to 100% in the reported radiopharmaceutical activity. The suggested DRL for 18F-FDG/PET activity was 5.54 MBq.kg–1 (0.149 mCi.kg–1). Conclusion The present study has demonstrated the lack of standardization in administered radiopharmaceutical activities for PET procedures in Brazil, corroborating the necessity of an official DRL value to be adopted in the country. The suggested DLR value demonstrates that there is room for optimization of the procedures and 18F-FDG/PET activities administered in Brazilian clinics to reduce the doses delivered to patients. It is important to highlight that this value should be continually revised and optimized at least every five years. Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2013-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000500284Radiologia Brasileira v.46 n.5 2013reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/S0100-39842013000500004info:eu-repo/semantics/openAccessOliveira,Cássio MiriSá,Lidia Vasconcellos deAlonso,Thêssa CristinaSilva,Teógenes Augusto daeng2015-09-03T00:00:00Zoai:scielo:S0100-39842013000500284Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2015-09-03T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false |
dc.title.none.fl_str_mv |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
title |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
spellingShingle |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil Oliveira,Cássio Miri Nuclear medicine Positron emission tomography Diagnostic reference level Radiopharmaceutical 18F-FDG |
title_short |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
title_full |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
title_fullStr |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
title_full_unstemmed |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
title_sort |
Suggestion of a national diagnostic reference level for 18F-FDG/PET scans in adult cancer patients in Brazil |
author |
Oliveira,Cássio Miri |
author_facet |
Oliveira,Cássio Miri Sá,Lidia Vasconcellos de Alonso,Thêssa Cristina Silva,Teógenes Augusto da |
author_role |
author |
author2 |
Sá,Lidia Vasconcellos de Alonso,Thêssa Cristina Silva,Teógenes Augusto da |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Cássio Miri Sá,Lidia Vasconcellos de Alonso,Thêssa Cristina Silva,Teógenes Augusto da |
dc.subject.por.fl_str_mv |
Nuclear medicine Positron emission tomography Diagnostic reference level Radiopharmaceutical 18F-FDG |
topic |
Nuclear medicine Positron emission tomography Diagnostic reference level Radiopharmaceutical 18F-FDG |
description |
Objective To suggest a national value for the diagnostic reference level (DRL) in terms of activity in MBq.kg–1, for nuclear medicine procedures with fluorodeoxyglucose (18F-FDG) in whole body positron emission tomography (PET) scans of adult patients. Materials and Methods A survey on values of 18F-FDG activity administered in Brazilian clinics was undertaken by means of a questionnaire including questions about number and manufacturer of the installed equipment, model and detector type. The suggested DRL value was based on the calculation of the third quartile of the activity values distribution reported by the clinics. Results Among the surveyed Brazilian clinics, 58% responded completely or partially the questionnaire; and the results demonstrated variation of up to 100% in the reported radiopharmaceutical activity. The suggested DRL for 18F-FDG/PET activity was 5.54 MBq.kg–1 (0.149 mCi.kg–1). Conclusion The present study has demonstrated the lack of standardization in administered radiopharmaceutical activities for PET procedures in Brazil, corroborating the necessity of an official DRL value to be adopted in the country. The suggested DLR value demonstrates that there is room for optimization of the procedures and 18F-FDG/PET activities administered in Brazilian clinics to reduce the doses delivered to patients. It is important to highlight that this value should be continually revised and optimized at least every five years. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000500284 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842013000500284 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-39842013000500004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
publisher.none.fl_str_mv |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
dc.source.none.fl_str_mv |
Radiologia Brasileira v.46 n.5 2013 reponame:Radiologia Brasileira (Online) instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) instacron:CBR |
instname_str |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
instacron_str |
CBR |
institution |
CBR |
reponame_str |
Radiologia Brasileira (Online) |
collection |
Radiologia Brasileira (Online) |
repository.name.fl_str_mv |
Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) |
repository.mail.fl_str_mv |
radiologiabrasileira@cbr.org.br |
_version_ |
1754208938473029632 |