Can chest high-resolution computed tomography findings diagnose pulmonary alveolar microlithiasis?

• Autor(a) principal: Francisco,Flávia Angélica Ferreira
• Data de Publicação: 2015
• Outros Autores: Rodrigues,Rosana Souza, Barreto,Miriam Menna, Escuissato,Dante Luiz, Araujo Neto,Cesar Augusto, Silva,Jorge Luiz Pereira e, Silva,Claudio S., Hochhegger,Bruno, Souza Jr.,Arthur Soares, Zanetti,Gláucia, Marchiori,Edson
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Radiologia Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842015000400004
• topic: Pulmonary alveolar microlithiasis; High-resolution computed tomography; Pulmonary calcifications

Abstract Objective: The present study was aimed at retrospectively reviewing high-resolution computed tomography (HRCT) findings in patients with pulmonary alveolar microlithiasis in order to evaluate the frequency of tomographic findings and their distribution in the lung parenchyma. Materials and Methods: Thirteen patients (9 females and 4 males; age, 9 to 59 years; mean age, 34.5 years) were included in the present study. The HRCT images were independently evaluated by two observers whose decisions were made by consensus. The inclusion criterion was the presence of abnormalities typical of pulmonary alveolar microlithiasis at HRCT, which precludes lung biopsy. However, in 6 cases lung biopsy was performed. Results: Ground-glass opacities and small parenchymal nodules were the predominant tomographic findings, present in 100% of cases, followed by small subpleural nodules (92.3%), subpleural cysts (84.6%), subpleural linear calcifications (69.2%), crazy-paving pattern (69.2%), fissure nodularity (53.8%), calcification along interlobular septa (46.2%) and dense consolidation (46.2%). Conclusion: As regards distribution of the lesions, there was preferential involvement of the lower third of the lungs. No predominance of distribution in axial and anteroposterior directions was observed.