Juvenile stress of short frequency and intensity does not affect rats´ brain white matter

Detalhes bibliográficos
Autor(a) principal: Lima, Vivian Fuguhara de
Data de Publicação: 2022
Outros Autores: Kato, Kathia Terumi, Barilli, Letícia Alexandrino, Melo, Silvana Regina de
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Saúde e Pesquisa (Online)
Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469
Resumo: The current study evaluates the lasting effects of two types of stress on the corpus callosum (CC). Forty-two male Wistar rats were randomly divided into three groups: Control Group (CG), Physical Stress (FS, immobilization) and Psychological Stress (PS, exposure to predators). Stress procedures occurred for three consecutive days at the juvenile stage (P25-P27) and analyzed at the adult age (P74); brains were retrieved and processed by Klüver-Barrera technique and sections were analyzed by morphometry. Results showed that there were no changes in the general aspects such as animal weight, and in the histological aspects such as CC thickness and quantity of the region´s glia nuclei. Current research suggests that the lasting effects of both models of juvenile stress of short frequency (3 days) and intensity (90 minutes/FS and 20 minutes/PS) were neither detrimental nor protective, featuring a positive adaptation.
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spelling Juvenile stress of short frequency and intensity does not affect rats´ brain white matterEstresse juvenil de curta frequência e intensidade não afeta a substância branca cerebral de ratosCorpus callosumImmobilizationMyelinOligodendrocytesPsychologic stressMorphological sciencesCorpo calosoEstresse psicológicoImobilizaçãoMielinaOligodendrócitosCiências morfológicasThe current study evaluates the lasting effects of two types of stress on the corpus callosum (CC). Forty-two male Wistar rats were randomly divided into three groups: Control Group (CG), Physical Stress (FS, immobilization) and Psychological Stress (PS, exposure to predators). Stress procedures occurred for three consecutive days at the juvenile stage (P25-P27) and analyzed at the adult age (P74); brains were retrieved and processed by Klüver-Barrera technique and sections were analyzed by morphometry. Results showed that there were no changes in the general aspects such as animal weight, and in the histological aspects such as CC thickness and quantity of the region´s glia nuclei. Current research suggests that the lasting effects of both models of juvenile stress of short frequency (3 days) and intensity (90 minutes/FS and 20 minutes/PS) were neither detrimental nor protective, featuring a positive adaptation.O objetivo deste estudo foi avaliar os efeitos duradouros de dois tipos de estresse sobre o corpo caloso (CC). Foram estudados 42 ratos Wistar machos divididos aleatoriamente em três grupos: Grupo Controle (GC), Estresse Físico (EF, imobilização) e Estresse Psicológico (EP, exposição ao predador). Os procedimentos de estresse ocorreram durante três dias consecutivos na idade juvenil (P25-P27) e foram analisados na idade adulta (P74). Os cérebros foram coletados, processados com a técnica de Klüver-Barrera, e secções foram analisadas por meio de morfometria. Os resultados demonstraram que não houve alterações em aspectos gerais como peso dos animais, e histológicos como espessura do CC e quantidade dos núcleos gliais nesta região. O estudo sugere que os efeitos duradouros de ambos os modelos de estresse juvenil de curta frequência (3 dias) e intensidade (90 minutos/EF e 20 minutos/EP) não foram nem prejudiciais e nem protetores, o que pode ser considerado uma adaptação positiva.Universidade Cesumar - UniCesumar2022-04-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por Paresapplication/pdfapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/1046910.17765/2176-9206.2022v15n2.e10469Saúde e Pesquisa; Vol 15 No 2 (2022): abr./jun. - Ahead of print; 1-12Saúde e Pesquisa; v. 15 n. 2 (2022): abr./jun. - Ahead of print; 1-122176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporenghttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469/7060https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469/7061Copyright (c) 2022 Saúde e Pesquisahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLima, Vivian Fuguhara de Kato, Kathia TerumiBarilli, Letícia Alexandrino Melo, Silvana Regina de2022-05-04T17:42:07Zoai:ojs.pkp.sfu.ca:article/10469Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2022-05-04T17:42:07Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse
dc.title.none.fl_str_mv Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
Estresse juvenil de curta frequência e intensidade não afeta a substância branca cerebral de ratos
title Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
spellingShingle Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
Lima, Vivian Fuguhara de
Corpus callosum
Immobilization
Myelin
Oligodendrocytes
Psychologic stress
Morphological sciences
Corpo caloso
Estresse psicológico
Imobilização
Mielina
Oligodendrócitos
Ciências morfológicas
title_short Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
title_full Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
title_fullStr Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
title_full_unstemmed Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
title_sort Juvenile stress of short frequency and intensity does not affect rats´ brain white matter
author Lima, Vivian Fuguhara de
author_facet Lima, Vivian Fuguhara de
Kato, Kathia Terumi
Barilli, Letícia Alexandrino
Melo, Silvana Regina de
author_role author
author2 Kato, Kathia Terumi
Barilli, Letícia Alexandrino
Melo, Silvana Regina de
author2_role author
author
author
dc.contributor.author.fl_str_mv Lima, Vivian Fuguhara de
Kato, Kathia Terumi
Barilli, Letícia Alexandrino
Melo, Silvana Regina de
dc.subject.por.fl_str_mv Corpus callosum
Immobilization
Myelin
Oligodendrocytes
Psychologic stress
Morphological sciences
Corpo caloso
Estresse psicológico
Imobilização
Mielina
Oligodendrócitos
Ciências morfológicas
topic Corpus callosum
Immobilization
Myelin
Oligodendrocytes
Psychologic stress
Morphological sciences
Corpo caloso
Estresse psicológico
Imobilização
Mielina
Oligodendrócitos
Ciências morfológicas
description The current study evaluates the lasting effects of two types of stress on the corpus callosum (CC). Forty-two male Wistar rats were randomly divided into three groups: Control Group (CG), Physical Stress (FS, immobilization) and Psychological Stress (PS, exposure to predators). Stress procedures occurred for three consecutive days at the juvenile stage (P25-P27) and analyzed at the adult age (P74); brains were retrieved and processed by Klüver-Barrera technique and sections were analyzed by morphometry. Results showed that there were no changes in the general aspects such as animal weight, and in the histological aspects such as CC thickness and quantity of the region´s glia nuclei. Current research suggests that the lasting effects of both models of juvenile stress of short frequency (3 days) and intensity (90 minutes/FS and 20 minutes/PS) were neither detrimental nor protective, featuring a positive adaptation.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469
10.17765/2176-9206.2022v15n2.e10469
url https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469
identifier_str_mv 10.17765/2176-9206.2022v15n2.e10469
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469/7060
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/10469/7061
dc.rights.driver.fl_str_mv Copyright (c) 2022 Saúde e Pesquisa
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Saúde e Pesquisa
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
dc.source.none.fl_str_mv Saúde e Pesquisa; Vol 15 No 2 (2022): abr./jun. - Ahead of print; 1-12
Saúde e Pesquisa; v. 15 n. 2 (2022): abr./jun. - Ahead of print; 1-12
2176-9206
reponame:Saúde e Pesquisa (Online)
instname:Cesumar Diretoria de Pesquisa
instacron:CESUMAR
instname_str Cesumar Diretoria de Pesquisa
instacron_str CESUMAR
institution CESUMAR
reponame_str Saúde e Pesquisa (Online)
collection Saúde e Pesquisa (Online)
repository.name.fl_str_mv Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa
repository.mail.fl_str_mv naep@cesumar.br
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