Techniques and Perspectives in Cancer Immunotherapy
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Data de Publicação: | 2012 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Saúde e Pesquisa (Online) |
Texto Completo: | https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172 |
Resumo: | Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses. |
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Techniques and Perspectives in Cancer ImmunotherapyTécnicas e Perspectivas em Imunoterapia do CâncerImmunotherapyCancerVaccinesImunoterapiaCâncerVacinas.Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses.Os tumores malignos são um dos principais focos da imunoterapia, não apenas no tratamento, mas também na sua prevenção. Embora as células cancerosas sejam menos imunogênicas do que microorganismos, o sistema imunológico é capaz de reconhecer e eliminar células tumorais. Entretanto, assim como os parasitas desenvolvem mecanismos de escape ao sistema imune, os tumores também conseguem evadir-se de diversas maneiras, muitas vezes interferindo nas respostas imunes contra eles. Nos últimos anos, a imunoterapia do câncer vem obtendo significativos avanços, aplicando os conhecimentos de imunologia celular e molecular para o desenvolvimento de estratégias imunomoduladoras eficazes e seguras, aumentando as respostas antitumorais.Universidade Cesumar - UniCesumar2012-09-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literatura;application/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172Saúde e Pesquisa; Vol 5 No 3 (2012): set./dez.Saúde e Pesquisa; v. 5 n. 3 (2012): set./dez.2176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172/1811Giacomini, GiovanaMenezes, Herculesinfo:eu-repo/semantics/openAccess2020-09-04T20:37:18Zoai:ojs.pkp.sfu.ca:article/2172Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2020-09-04T20:37:18Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse |
dc.title.none.fl_str_mv |
Techniques and Perspectives in Cancer Immunotherapy Técnicas e Perspectivas em Imunoterapia do Câncer |
title |
Techniques and Perspectives in Cancer Immunotherapy |
spellingShingle |
Techniques and Perspectives in Cancer Immunotherapy Giacomini, Giovana Immunotherapy Cancer Vaccines Imunoterapia Câncer Vacinas . |
title_short |
Techniques and Perspectives in Cancer Immunotherapy |
title_full |
Techniques and Perspectives in Cancer Immunotherapy |
title_fullStr |
Techniques and Perspectives in Cancer Immunotherapy |
title_full_unstemmed |
Techniques and Perspectives in Cancer Immunotherapy |
title_sort |
Techniques and Perspectives in Cancer Immunotherapy |
author |
Giacomini, Giovana |
author_facet |
Giacomini, Giovana Menezes, Hercules |
author_role |
author |
author2 |
Menezes, Hercules |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Giacomini, Giovana Menezes, Hercules |
dc.subject.por.fl_str_mv |
Immunotherapy Cancer Vaccines Imunoterapia Câncer Vacinas . |
topic |
Immunotherapy Cancer Vaccines Imunoterapia Câncer Vacinas . |
description |
Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Revisão de Literatura; |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172 |
url |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172/1811 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Cesumar - UniCesumar |
publisher.none.fl_str_mv |
Universidade Cesumar - UniCesumar |
dc.source.none.fl_str_mv |
Saúde e Pesquisa; Vol 5 No 3 (2012): set./dez. Saúde e Pesquisa; v. 5 n. 3 (2012): set./dez. 2176-9206 reponame:Saúde e Pesquisa (Online) instname:Cesumar Diretoria de Pesquisa instacron:CESUMAR |
instname_str |
Cesumar Diretoria de Pesquisa |
instacron_str |
CESUMAR |
institution |
CESUMAR |
reponame_str |
Saúde e Pesquisa (Online) |
collection |
Saúde e Pesquisa (Online) |
repository.name.fl_str_mv |
Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa |
repository.mail.fl_str_mv |
naep@cesumar.br |
_version_ |
1754122532506566656 |