Techniques and Perspectives in Cancer Immunotherapy

Detalhes bibliográficos
Autor(a) principal: Giacomini, Giovana
Data de Publicação: 2012
Outros Autores: Menezes, Hercules
Tipo de documento: Artigo
Idioma: por
Título da fonte: Saúde e Pesquisa (Online)
Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172
Resumo: Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses.
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spelling Techniques and Perspectives in Cancer ImmunotherapyTécnicas e Perspectivas em Imunoterapia do CâncerImmunotherapyCancerVaccinesImunoterapiaCâncerVacinas.Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses.Os tumores malignos são um dos principais focos da imunoterapia, não apenas no tratamento, mas também na sua prevenção. Embora as células cancerosas sejam menos imunogênicas do que microorganismos, o sistema imunológico é capaz de reconhecer e eliminar células tumorais. Entretanto, assim como os parasitas desenvolvem mecanismos de escape ao sistema imune, os tumores também conseguem evadir-se de diversas maneiras, muitas vezes interferindo nas respostas imunes contra eles. Nos últimos anos, a imunoterapia do câncer vem obtendo significativos avanços, aplicando os conhecimentos de imunologia celular e molecular para o desenvolvimento de estratégias imunomoduladoras eficazes e seguras, aumentando as respostas antitumorais.Universidade Cesumar - UniCesumar2012-09-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literatura;application/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172Saúde e Pesquisa; Vol 5 No 3 (2012): set./dez.Saúde e Pesquisa; v. 5 n. 3 (2012): set./dez.2176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172/1811Giacomini, GiovanaMenezes, Herculesinfo:eu-repo/semantics/openAccess2020-09-04T20:37:18Zoai:ojs.pkp.sfu.ca:article/2172Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2020-09-04T20:37:18Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse
dc.title.none.fl_str_mv Techniques and Perspectives in Cancer Immunotherapy
Técnicas e Perspectivas em Imunoterapia do Câncer
title Techniques and Perspectives in Cancer Immunotherapy
spellingShingle Techniques and Perspectives in Cancer Immunotherapy
Giacomini, Giovana
Immunotherapy
Cancer
Vaccines
Imunoterapia
Câncer
Vacinas
.
title_short Techniques and Perspectives in Cancer Immunotherapy
title_full Techniques and Perspectives in Cancer Immunotherapy
title_fullStr Techniques and Perspectives in Cancer Immunotherapy
title_full_unstemmed Techniques and Perspectives in Cancer Immunotherapy
title_sort Techniques and Perspectives in Cancer Immunotherapy
author Giacomini, Giovana
author_facet Giacomini, Giovana
Menezes, Hercules
author_role author
author2 Menezes, Hercules
author2_role author
dc.contributor.author.fl_str_mv Giacomini, Giovana
Menezes, Hercules
dc.subject.por.fl_str_mv Immunotherapy
Cancer
Vaccines
Imunoterapia
Câncer
Vacinas
.
topic Immunotherapy
Cancer
Vaccines
Imunoterapia
Câncer
Vacinas
.
description Malign tumors are the main focus of immunotherapy for treatment and prevention. Although cancerous cells are less immunogenic than microorganisms, the immunological system recognizes and eliminates tumor cells. However, similar to the activity of parasites that develop escape mechanisms to the immune system, tumors also evade in several ways and frequently interfere in the immune responses against them. In recent years, much progress has been made in cancer immunotherapy through a deeper knowledge on cell and molecular immunology for the development of efficacious and warranted immune-modulating strategies, with an increase in anti-tumor responses.
publishDate 2012
dc.date.none.fl_str_mv 2012-09-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de Literatura;
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172
url https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2172/1811
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
dc.source.none.fl_str_mv Saúde e Pesquisa; Vol 5 No 3 (2012): set./dez.
Saúde e Pesquisa; v. 5 n. 3 (2012): set./dez.
2176-9206
reponame:Saúde e Pesquisa (Online)
instname:Cesumar Diretoria de Pesquisa
instacron:CESUMAR
instname_str Cesumar Diretoria de Pesquisa
instacron_str CESUMAR
institution CESUMAR
reponame_str Saúde e Pesquisa (Online)
collection Saúde e Pesquisa (Online)
repository.name.fl_str_mv Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa
repository.mail.fl_str_mv naep@cesumar.br
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