Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats

Detalhes bibliográficos
Autor(a) principal: Marques, Any de Castro Ruiz
Data de Publicação: 2015
Outros Autores: Gabbiatti, Gabrielle Cristine, Gravena, Ângela Andréia França, Amaral, Valéria do
Tipo de documento: Artigo
Idioma: por
Título da fonte: Saúde e Pesquisa (Online)
Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481
Resumo: Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.
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spelling Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in RatsInfluência das Dietas Hipercalóricas sobre os Parâmetros de Obesidade, Dislipidemia e Hiperglicemia em RatosDyslipidemiaHyperglycemiaObesityRats.DislipidemiasHiperglicemiaObesidadeRatosDyslipidemiaHyperglycemiaObesityRatsHypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.Este estudo teve como objetivo induzir dietas hipercalóricas em ratos para promover a obesidade e verificar seus níveis bioquímicos, relacionando-os com ratos alimentados por dieta padrão. Foram utilizados 30 ratos, pesando entre 250 e 300 g. Os ratos foram divididos em dois grupos: Dieta Padrão (SD) e Dieta Cafeteria (CD). Após 30 dias, os grupos foram divididos em: SD, Dieta Plus (PD) e CD. Em 30 e 60 dias, realizaram-se as dosagens bioquímicas. Os animais foram pesados, medidos e realizaram-se os Índices de Lee e a análise macroscópica da gordura visceral. Os valores de peso, circunferência, tamanho e Índice de Lee, aumentaram nos animais da PD em 30 e 60 dias de dieta. Os parâmetros bioquímicos em 30 dias aumentaram os níveis de colesterol total e HDL do grupo SD em relação à PD e CD. Em 60 dias o colesterol total e HDL sofreram uma diminuição. Os níveis de glicose em 30 dias aumentaram em relação aos grupos da PD e CD. Na análise macroscópica da gordura visceral, o grupo PD apresentou alteração visível em relação à SD. Ao induzir dietas em animais, estes apresentaram respostas diferentes através do metabolismo e do tempo de indução da dieta. Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats ABSTRACT: Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.Universidade Cesumar - UniCesumar2015-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa experimentalapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/248110.17765/1983-1870.2015v8n1p55-62Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 55-62Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 55-622176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481/2554Marques, Any de Castro RuizGabbiatti, Gabrielle CristineGravena, Ângela Andréia FrançaAmaral, Valéria doinfo:eu-repo/semantics/openAccess2021-03-26T18:16:34Zoai:ojs.pkp.sfu.ca:article/2481Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2021-03-26T18:16:34Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse
dc.title.none.fl_str_mv Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
Influência das Dietas Hipercalóricas sobre os Parâmetros de Obesidade, Dislipidemia e Hiperglicemia em Ratos
title Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
spellingShingle Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
Marques, Any de Castro Ruiz
Dyslipidemia
Hyperglycemia
Obesity
Rats.
Dislipidemias
Hiperglicemia
Obesidade
Ratos
Dyslipidemia
Hyperglycemia
Obesity
Rats
title_short Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
title_full Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
title_fullStr Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
title_full_unstemmed Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
title_sort Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
author Marques, Any de Castro Ruiz
author_facet Marques, Any de Castro Ruiz
Gabbiatti, Gabrielle Cristine
Gravena, Ângela Andréia França
Amaral, Valéria do
author_role author
author2 Gabbiatti, Gabrielle Cristine
Gravena, Ângela Andréia França
Amaral, Valéria do
author2_role author
author
author
dc.contributor.author.fl_str_mv Marques, Any de Castro Ruiz
Gabbiatti, Gabrielle Cristine
Gravena, Ângela Andréia França
Amaral, Valéria do
dc.subject.por.fl_str_mv Dyslipidemia
Hyperglycemia
Obesity
Rats.
Dislipidemias
Hiperglicemia
Obesidade
Ratos
Dyslipidemia
Hyperglycemia
Obesity
Rats
topic Dyslipidemia
Hyperglycemia
Obesity
Rats.
Dislipidemias
Hiperglicemia
Obesidade
Ratos
Dyslipidemia
Hyperglycemia
Obesity
Rats
description Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Pesquisa experimental
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481
10.17765/1983-1870.2015v8n1p55-62
url https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481
identifier_str_mv 10.17765/1983-1870.2015v8n1p55-62
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481/2554
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
dc.source.none.fl_str_mv Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 55-62
Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 55-62
2176-9206
reponame:Saúde e Pesquisa (Online)
instname:Cesumar Diretoria de Pesquisa
instacron:CESUMAR
instname_str Cesumar Diretoria de Pesquisa
instacron_str CESUMAR
institution CESUMAR
reponame_str Saúde e Pesquisa (Online)
collection Saúde e Pesquisa (Online)
repository.name.fl_str_mv Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa
repository.mail.fl_str_mv naep@cesumar.br
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