Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Saúde e Pesquisa (Online) |
Texto Completo: | https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481 |
Resumo: | Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time. |
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Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in RatsInfluência das Dietas Hipercalóricas sobre os Parâmetros de Obesidade, Dislipidemia e Hiperglicemia em RatosDyslipidemiaHyperglycemiaObesityRats.DislipidemiasHiperglicemiaObesidadeRatosDyslipidemiaHyperglycemiaObesityRatsHypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.Este estudo teve como objetivo induzir dietas hipercalóricas em ratos para promover a obesidade e verificar seus níveis bioquímicos, relacionando-os com ratos alimentados por dieta padrão. Foram utilizados 30 ratos, pesando entre 250 e 300 g. Os ratos foram divididos em dois grupos: Dieta Padrão (SD) e Dieta Cafeteria (CD). Após 30 dias, os grupos foram divididos em: SD, Dieta Plus (PD) e CD. Em 30 e 60 dias, realizaram-se as dosagens bioquímicas. Os animais foram pesados, medidos e realizaram-se os Índices de Lee e a análise macroscópica da gordura visceral. Os valores de peso, circunferência, tamanho e Índice de Lee, aumentaram nos animais da PD em 30 e 60 dias de dieta. Os parâmetros bioquímicos em 30 dias aumentaram os níveis de colesterol total e HDL do grupo SD em relação à PD e CD. Em 60 dias o colesterol total e HDL sofreram uma diminuição. Os níveis de glicose em 30 dias aumentaram em relação aos grupos da PD e CD. Na análise macroscópica da gordura visceral, o grupo PD apresentou alteração visível em relação à SD. Ao induzir dietas em animais, estes apresentaram respostas diferentes através do metabolismo e do tempo de indução da dieta. Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats ABSTRACT: Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time.Universidade Cesumar - UniCesumar2015-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa experimentalapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/248110.17765/1983-1870.2015v8n1p55-62Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 55-62Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 55-622176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481/2554Marques, Any de Castro RuizGabbiatti, Gabrielle CristineGravena, Ângela Andréia FrançaAmaral, Valéria doinfo:eu-repo/semantics/openAccess2021-03-26T18:16:34Zoai:ojs.pkp.sfu.ca:article/2481Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2021-03-26T18:16:34Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse |
dc.title.none.fl_str_mv |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats Influência das Dietas Hipercalóricas sobre os Parâmetros de Obesidade, Dislipidemia e Hiperglicemia em Ratos |
title |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
spellingShingle |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats Marques, Any de Castro Ruiz Dyslipidemia Hyperglycemia Obesity Rats. Dislipidemias Hiperglicemia Obesidade Ratos Dyslipidemia Hyperglycemia Obesity Rats |
title_short |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
title_full |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
title_fullStr |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
title_full_unstemmed |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
title_sort |
Influence of Hypercaloric Diets on the Parameters of Obesity, Dyslipidemia and Hyperglycemia in Rats |
author |
Marques, Any de Castro Ruiz |
author_facet |
Marques, Any de Castro Ruiz Gabbiatti, Gabrielle Cristine Gravena, Ângela Andréia França Amaral, Valéria do |
author_role |
author |
author2 |
Gabbiatti, Gabrielle Cristine Gravena, Ângela Andréia França Amaral, Valéria do |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Marques, Any de Castro Ruiz Gabbiatti, Gabrielle Cristine Gravena, Ângela Andréia França Amaral, Valéria do |
dc.subject.por.fl_str_mv |
Dyslipidemia Hyperglycemia Obesity Rats. Dislipidemias Hiperglicemia Obesidade Ratos Dyslipidemia Hyperglycemia Obesity Rats |
topic |
Dyslipidemia Hyperglycemia Obesity Rats. Dislipidemias Hiperglicemia Obesidade Ratos Dyslipidemia Hyperglycemia Obesity Rats |
description |
Hypercaloric diets were induced in rats to trigger obesity and analyze their biochemical levels. The rats were then compared with others fed on standard rations. Thirty rats, weighing 250-300 g, were used and divided into two groups: Standard Diet (SD) and Cafeteria Diet (CD). After 30 days, the groups were divided into SD, Diet Plus (PD) and CD; and biochemical tests were undertaken after 30 and 60 days. The animals were weighed, measured and the Lee Index and the microscopic analysis of visceral fat were taken. Weight, circumference, size and Lee Index increased in PD animals after 30 and 60 days of diet. In 30 days the chemical parameters increased total cholesterol and HDL levels of group SD when compared to PD and CD. Total cholesterol and HDL decreased after 60 days. Glucose levels increased after 30 days when compared to groups PD and CD. Group PD had a clear change in the microscopic analysis of visceral fat when compared to SD. Induced diet in animals had different reactions due to metabolism and induction time. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pesquisa experimental |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481 10.17765/1983-1870.2015v8n1p55-62 |
url |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481 |
identifier_str_mv |
10.17765/1983-1870.2015v8n1p55-62 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/2481/2554 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Cesumar - UniCesumar |
publisher.none.fl_str_mv |
Universidade Cesumar - UniCesumar |
dc.source.none.fl_str_mv |
Saúde e Pesquisa; Vol 8 No 1 (2015): jan./abr.; 55-62 Saúde e Pesquisa; v. 8 n. 1 (2015): jan./abr.; 55-62 2176-9206 reponame:Saúde e Pesquisa (Online) instname:Cesumar Diretoria de Pesquisa instacron:CESUMAR |
instname_str |
Cesumar Diretoria de Pesquisa |
instacron_str |
CESUMAR |
institution |
CESUMAR |
reponame_str |
Saúde e Pesquisa (Online) |
collection |
Saúde e Pesquisa (Online) |
repository.name.fl_str_mv |
Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa |
repository.mail.fl_str_mv |
naep@cesumar.br |
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1754122532873568256 |