ANTIMICROBIAL SUSCEPTIBILIT Y OF BACTERIA IN CHRONIC ULCERS TO CRUDE EXTRACTS OF Prosopis juliflora

• Autor(a) principal: Silva, Renata Soares da
• Data de Publicação: 2015
• Outros Autores: Oliveira, Karla Maria Santos de, Cavalcante, Giani Maria
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde e Pesquisa (Online)
• Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/4488
• topic: Prosopis juliflora; Úlceras crônicas; Atividade antimicrobiana

Chronic ulcers are prone to infection due to the sterile lossof the innate barrier of the skin and cutaneous annexes, coupled to the development of microbial communities. Current study investigates the susceptibility of bacteria associated with chronic ulcers to crude extracts of Prosopis juliflora. In vitro tests with the crude extracts of leaves and stem bark were performed against strains of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 25923) and Proteus mirabilis (ATCC 7002), by a diffusion assay in agar and determination of Minimum Inhibiory Concentration (MIC). Results showed that E. coli, P. aeruginosa, S. aureus and P.mirabilis strains were affected by the crude extracts of the leaves, with a diameter of the inhibition zone measuring respectively 21.0; 33.0; 20.0; 21.0 mm, whereas E. coli and S. aureus were more affected to the crude extracts of the stem bark, with an inhibition zone diameter of 21.5 and 20.0 mm, respectively. Best MIC rates were reported for the crude extracts of P. juliflora leaves. Chemical studies for the extraction and isolation of compounds are recommended for the execution of in vitro assays to investigate the compounds´ antimicrobial activity.