Acute kidney injury and hypercalcemia associated with veterinary supplements applications in adult man

• Autor(a) principal: Frutuoso Bezerra, Rádames
• Data de Publicação: 2024
• Outros Autores: de Souza Andrade, Tacilla Hanny, Bezerra de Araújo, Flávio, Lima, Rafael Siqueira
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Journal of Health & Biological Sciences
• Texto Completo: https://periodicos.unichristus.edu.br/jhbs/article/view/5098
• topic: acute kidney injury; chronic kidney disease; hypercalcemia; nephrolithiasis; veterinary drugs

The compound “ADE” is an injectable oil for veterinary use which contains large amounts of vitamins A, D and E. The parenteral application in humans leads to a granuloma reaction which triggers hypercalcemia. A 42-year-old man was admitted with lower limb pain, nephrolithiasis and nephrocalcinosis. Laboratory tests revealed creatinine 4.59 mg/dl, calcium 13.3 mg/dl and parathormone 13.8 pg/ml. He underwent an ureterolithotripsy, stent placement, intravenous crystalloid fluids, and corticosteroid. He improved symptoms, kidney function and normalized serum calcium. The “ADE”-induced hypercalcemia diagnosis can be challenging. The early diagnosis may avoid negative outcomes.