Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis

Detalhes bibliográficos
Autor(a) principal: Soares, Deivid Costa
Data de Publicação: 2012
Outros Autores: Silva, Teresa C. Calegari, Lopes, Ulisses G., Teixeira, Valéria L., Paixão, Izabel C. N. de Palmer, Santos, Claudio Cirne, Bou-Habib, Dumith Chequer, Saraiva, Elvira M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/18602
Resumo: Universidade Federal do Rio de Janeiro, Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.
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spelling Soares, Deivid CostaSilva, Teresa C. CalegariLopes, Ulisses G.Teixeira, Valéria L.Paixão, Izabel C. N. de PalmerSantos, Claudio CirneBou-Habib, Dumith ChequerSaraiva, Elvira M.2017-04-20T17:42:12Z2017-04-20T17:42:12Z2012SOARES, Deivid Costa; et al. Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis. PLoS Negl Trop Dis., v.6, n.9, e1787, 12p, Sept. 2012.1935-2727https://www.arca.fiocruz.br/handle/icict/1860210.1371/journal.pntd.00017871935-2735engPublic Library of ScienceLieshmaniaDolabelladienetriolTratamentoLeishmania amazonensisDolabelladienetriolTreatmentDolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro, Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Parasitologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Parasitologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Biologia. Departamento de Biologia Marinha. Niterói, RJ, Brasil.Universidade Federal Fluminense. Instituto de Biologia. Departamento de Biologia Celular e Molecular. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Universidade Federal do Rio de Janeiro, Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Chemotherapy for leishmaniasis, a disease caused by Leishmania parasites, is expensive and causes side effects. Furthermore, parasite resistance constitutes an increasing problem, and new drugs against this disease are needed. In this study, we examine the effect of the compound 8,10,18-trihydroxy-2,6-dolabelladiene (Dolabelladienetriol), on Leishmania growth in macrophages. The ability of this compound to modulate macrophage function is also described.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18602/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALdumith_bouhabib_etal_IOC_2012.pdfdumith_bouhabib_etal_IOC_2012.pdfapplication/pdf791887https://www.arca.fiocruz.br/bitstream/icict/18602/2/dumith_bouhabib_etal_IOC_2012.pdfcd9a2a4dad86233da708bfa375eff2eaMD52TEXTdumith_bouhabib_etal_IOC_2012.pdf.txtdumith_bouhabib_etal_IOC_2012.pdf.txtExtracted texttext/plain52352https://www.arca.fiocruz.br/bitstream/icict/18602/3/dumith_bouhabib_etal_IOC_2012.pdf.txt4715cd1ecfa9525665d570fcdd4c9da2MD53icict/186022023-09-14 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dc.title.pt_BR.fl_str_mv Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
title Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
spellingShingle Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
Soares, Deivid Costa
Lieshmania
Dolabelladienetriol
Tratamento
Leishmania amazonensis
Dolabelladienetriol
Treatment
title_short Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
title_full Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
title_fullStr Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
title_full_unstemmed Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
title_sort Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis
author Soares, Deivid Costa
author_facet Soares, Deivid Costa
Silva, Teresa C. Calegari
Lopes, Ulisses G.
Teixeira, Valéria L.
Paixão, Izabel C. N. de Palmer
Santos, Claudio Cirne
Bou-Habib, Dumith Chequer
Saraiva, Elvira M.
author_role author
author2 Silva, Teresa C. Calegari
Lopes, Ulisses G.
Teixeira, Valéria L.
Paixão, Izabel C. N. de Palmer
Santos, Claudio Cirne
Bou-Habib, Dumith Chequer
Saraiva, Elvira M.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Soares, Deivid Costa
Silva, Teresa C. Calegari
Lopes, Ulisses G.
Teixeira, Valéria L.
Paixão, Izabel C. N. de Palmer
Santos, Claudio Cirne
Bou-Habib, Dumith Chequer
Saraiva, Elvira M.
dc.subject.other.pt_BR.fl_str_mv Lieshmania
Dolabelladienetriol
Tratamento
topic Lieshmania
Dolabelladienetriol
Tratamento
Leishmania amazonensis
Dolabelladienetriol
Treatment
dc.subject.en.pt_BR.fl_str_mv Leishmania amazonensis
Dolabelladienetriol
Treatment
description Universidade Federal do Rio de Janeiro, Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2017-04-20T17:42:12Z
dc.date.available.fl_str_mv 2017-04-20T17:42:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SOARES, Deivid Costa; et al. Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis. PLoS Negl Trop Dis., v.6, n.9, e1787, 12p, Sept. 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/18602
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0001787
dc.identifier.eissn.none.fl_str_mv 1935-2735
identifier_str_mv SOARES, Deivid Costa; et al. Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis. PLoS Negl Trop Dis., v.6, n.9, e1787, 12p, Sept. 2012.
1935-2727
10.1371/journal.pntd.0001787
1935-2735
url https://www.arca.fiocruz.br/handle/icict/18602
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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