SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight

Detalhes bibliográficos
Autor(a) principal: Angeletti, Silvia
Data de Publicação: 2022
Outros Autores: Giovanetti, Marta, Fogolari, Marta, Cella, Eleonora, Florio, Lucia de, Lintas, Carla, Veralli, Roberta, Francesconi, Maria, Caccuri, Francesca, De Cesaris, Marina, De Flora, Cecilia, Ceccarelli, Giancarlo, Spoto, Silvia, Caruso, Arnaldo, Pascarella, Stefano, Riva, Elisabetta, Ciccozzi, Massimo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1002/jmv.27451
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56214
Resumo: Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.
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spelling Angeletti, SilviaGiovanetti, MartaFogolari, MartaCella, EleonoraFlorio, Lucia deLintas, CarlaVeralli, RobertaFrancesconi, MariaCaccuri, FrancescaDe Cesaris, MarinaDe Flora, CeciliaCeccarelli, GiancarloSpoto, SilviaCaruso, ArnaldoPascarella, StefanoRiva, ElisabettaCiccozzi, Massimo2022-12-26T15:04:43Z2022-12-26T15:04:43Z2022ANGELETTI, Silvia et al. SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight. Journal of Medical Virology, v. 94, p. 1689-1692, 2022.1096-9071https://www.arca.fiocruz.br/handle/icict/5621410.1002/jmv.27451engWiley Periodicals LLCSARS‐CoV‐2Vigilância genômicaItáliaVariante AY.4.2AY.4.2 variantGenomic surveillanceItalySARS‐CoV‐2SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insightinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUnit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Department of Molecular and Translational Medicine, Section of Microbiology, University of Brescia, Brescia, Italy.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.Department of Public Health and Infectious Diseases, Policlinico Umberto I Università ‘Sapienza', Rome, Italy.Diagnostic and Therapeutic Medicine Division, University Campus Bio‐Medico of Rome, Rome, Italy.Department of Molecular and Translational Medicine, Section of Microbiology, University of Brescia, Brescia, Italy.Department of Biochemical Sciences "A. Rossi Fanelli", University of Rome “La Sapienza”, Rome, Italy.Unit of Virology, University Campus Bio‐Medico of Rome, Rome, Italy.Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio‐Medico of Rome, Rome, Italy.The appearance of emerging variants of SARS‐CoV‐2 carrying mutations into the spike protein has recently raised concern with respect to tracking their transmission and mitigating the impact in the evolving pandemic across countries. AY.4.2, a recently detected Delta variant sublineage, is considered a new variant under investigation (VUI) as it carries specific genetic signatures present in the spike protein, called Y145H and A222V. Here, using genomic epidemiology, we provide the first preliminary insight regarding the circulation of this emerging VUI in Italy.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56214/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSilviaAngeletti_FrancescaCaccuri_MartaGiovanetti_etal_IOC_2022.pdfSilviaAngeletti_FrancescaCaccuri_MartaGiovanetti_etal_IOC_2022.pdfapplication/pdf1034597https://www.arca.fiocruz.br/bitstream/icict/56214/2/SilviaAngeletti_FrancescaCaccuri_MartaGiovanetti_etal_IOC_2022.pdf5436bc8fa69315a1d78c9255656edf21MD52icict/562142023-09-04 11:03:16.613oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T14:03:16Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en_US.fl_str_mv SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
title SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
spellingShingle SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
Angeletti, Silvia
SARS‐CoV‐2
Vigilância genômica
Itália
Variante AY.4.2
AY.4.2 variant
Genomic surveillance
Italy
SARS‐CoV‐2
title_short SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
title_full SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
title_fullStr SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
title_full_unstemmed SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
title_sort SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight
author Angeletti, Silvia
author_facet Angeletti, Silvia
Giovanetti, Marta
Fogolari, Marta
Cella, Eleonora
Florio, Lucia de
Lintas, Carla
Veralli, Roberta
Francesconi, Maria
Caccuri, Francesca
De Cesaris, Marina
De Flora, Cecilia
Ceccarelli, Giancarlo
Spoto, Silvia
Caruso, Arnaldo
Pascarella, Stefano
Riva, Elisabetta
Ciccozzi, Massimo
author_role author
author2 Giovanetti, Marta
Fogolari, Marta
Cella, Eleonora
Florio, Lucia de
Lintas, Carla
Veralli, Roberta
Francesconi, Maria
Caccuri, Francesca
De Cesaris, Marina
De Flora, Cecilia
Ceccarelli, Giancarlo
Spoto, Silvia
Caruso, Arnaldo
Pascarella, Stefano
Riva, Elisabetta
Ciccozzi, Massimo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Angeletti, Silvia
Giovanetti, Marta
Fogolari, Marta
Cella, Eleonora
Florio, Lucia de
Lintas, Carla
Veralli, Roberta
Francesconi, Maria
Caccuri, Francesca
De Cesaris, Marina
De Flora, Cecilia
Ceccarelli, Giancarlo
Spoto, Silvia
Caruso, Arnaldo
Pascarella, Stefano
Riva, Elisabetta
Ciccozzi, Massimo
dc.subject.other.en_US.fl_str_mv SARS‐CoV‐2
Vigilância genômica
Itália
Variante AY.4.2
topic SARS‐CoV‐2
Vigilância genômica
Itália
Variante AY.4.2
AY.4.2 variant
Genomic surveillance
Italy
SARS‐CoV‐2
dc.subject.en.en_US.fl_str_mv AY.4.2 variant
Genomic surveillance
Italy
SARS‐CoV‐2
description Unit of Clinical Laboratory Science, University Campus Bio‐Medico of Rome, Rome, Italy.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-12-26T15:04:43Z
dc.date.available.fl_str_mv 2022-12-26T15:04:43Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANGELETTI, Silvia et al. SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight. Journal of Medical Virology, v. 94, p. 1689-1692, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56214
dc.identifier.issn.en_US.fl_str_mv 1096-9071
dc.identifier.doi.none.fl_str_mv 10.1002/jmv.27451
identifier_str_mv ANGELETTI, Silvia et al. SARS‐CoV‐2 AY.4.2 variant circulating in Italy: Genomic preliminary insight. Journal of Medical Virology, v. 94, p. 1689-1692, 2022.
1096-9071
10.1002/jmv.27451
url https://www.arca.fiocruz.br/handle/icict/56214
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley Periodicals LLC
publisher.none.fl_str_mv Wiley Periodicals LLC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56214/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56214/2/SilviaAngeletti_FrancescaCaccuri_MartaGiovanetti_etal_IOC_2022.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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