The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells

Detalhes bibliográficos
Autor(a) principal: Dantas, Andréia Pires
Data de Publicação: 2006
Outros Autores: Salomão, Kelly, Barbosa, Helene Santos, Castro, Solange Lisboa de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35842
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.
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spelling Dantas, Andréia PiresSalomão, KellyBarbosa, Helene SantosCastro, Solange Lisboa de2019-09-24T13:35:59Z2019-09-24T13:35:59Z2006DANTAS, Andréia Pires et al. The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 101, n. 2, p. 207-211, Mar. 2006.0074-0276https://www.arca.fiocruz.br/handle/icict/3584210.1590/s0074-027620060002000131678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzTrypanosoma cruziPrópolisProdutos naturaisDoença de ChagasPropolisNatural productsTrypanosoma cruziChagas DiseaseThe effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cellsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Estrutural. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.Propolis has shown activity against pathogenic microorganisms that cause diseases in humans and animals. The ethanol (Et-Blg) and acetone (Ket-Blg) extracts from a Bulgarian propolis, with known chemical compositions, presented similar activity against tissue culture-derived amastigotes. The treatment of Trypanosoma cruzi-infected skeletal muscle cells with Et-Blg led to a decrease of infection and of the intracellular proliferation of amastigotes, while damage to the host cell was observed only at concentration 12.5 times higher than those affecting the parasite. Ultrastructural analysis of the effect of both extracts in epimastigotes revealed that the main targets were the mitochondrion and reservosomes. Et-Blg also affected the mitochondrion-kinetoplast complex in trypomastigotes, offering a potential target for chemotherapeutic agents.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/35842/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSolangeLCastro_KellySalomao_etal_IOC2006.pdfSolangeLCastro_KellySalomao_etal_IOC2006.pdfapplication/pdf560853https://www.arca.fiocruz.br/bitstream/icict/35842/2/SolangeLCastro_KellySalomao_etal_IOC2006.pdfd950e1df39b2da91e038159244e63ed2MD52TEXTSolangeLCastro_KellySalomao_etal_IOC2006.pdf.txtSolangeLCastro_KellySalomao_etal_IOC2006.pdf.txtExtracted texttext/plain21262https://www.arca.fiocruz.br/bitstream/icict/35842/3/SolangeLCastro_KellySalomao_etal_IOC2006.pdf.txtedb83f0099200bcb21a0473b7d027fceMD53icict/358422020-02-12 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dc.title.pt_BR.fl_str_mv The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
title The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
spellingShingle The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
Dantas, Andréia Pires
Trypanosoma cruzi
Própolis
Produtos naturais
Doença de Chagas
Propolis
Natural products
Trypanosoma cruzi
Chagas Disease
title_short The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
title_full The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
title_fullStr The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
title_full_unstemmed The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
title_sort The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
author Dantas, Andréia Pires
author_facet Dantas, Andréia Pires
Salomão, Kelly
Barbosa, Helene Santos
Castro, Solange Lisboa de
author_role author
author2 Salomão, Kelly
Barbosa, Helene Santos
Castro, Solange Lisboa de
author2_role author
author
author
dc.contributor.author.fl_str_mv Dantas, Andréia Pires
Salomão, Kelly
Barbosa, Helene Santos
Castro, Solange Lisboa de
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Própolis
Produtos naturais
Doença de Chagas
topic Trypanosoma cruzi
Própolis
Produtos naturais
Doença de Chagas
Propolis
Natural products
Trypanosoma cruzi
Chagas Disease
dc.subject.en.pt_BR.fl_str_mv Propolis
Natural products
Trypanosoma cruzi
Chagas Disease
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2019-09-24T13:35:59Z
dc.date.available.fl_str_mv 2019-09-24T13:35:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DANTAS, Andréia Pires et al. The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 101, n. 2, p. 207-211, Mar. 2006.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35842
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/s0074-02762006000200013
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv DANTAS, Andréia Pires et al. The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 101, n. 2, p. 207-211, Mar. 2006.
0074-0276
10.1590/s0074-02762006000200013
1678-8060
url https://www.arca.fiocruz.br/handle/icict/35842
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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