A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children

Detalhes bibliográficos
Autor(a) principal: Melo, Fabrício Freire de
Data de Publicação: 2012
Outros Autores: Rocha, Andreia Maria Camargos, Rocha, Gifone Aguiar, Pedroso, Silvia Helena Sousa Pietra, Batista, Sérgio de Assis, Castro, Lúcia Porto Fonseca de, Carvalho, Simone Diniz, Bittencourt, Paulo Fernando Souto, Oliveira, Celso Afonso de, Oliveira, Rodrigo Corrêa de, Queiroz, Dulciene Maria de Magalhães
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7748
Resumo: Universidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil
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spelling Melo, Fabrício Freire deRocha, Andreia Maria CamargosRocha, Gifone AguiarPedroso, Silvia Helena Sousa PietraBatista, Sérgio de AssisCastro, Lúcia Porto Fonseca deCarvalho, Simone DinizBittencourt, Paulo Fernando SoutoOliveira, Celso Afonso deOliveira, Rodrigo Corrêa deQueiroz, Dulciene Maria de Magalhães2014-06-02T14:18:17Z2014-06-02T14:18:17Z2012MELO, Fabrício Freire de et al. A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children. Microbes and Infection. 2012, vol.14, pp. 341-347.1286-4579https://www.arca.fiocruz.br/handle/icict/774810.1016/j.micinf.2011.11.008engElsevier Ltda.A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in childreninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Patologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Hospital Universitário. Serviço de Endoscopia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Hospital Universitário. Serviço de Endoscopia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, BrazilTh17 cells seem to have an important role in the efficacy of vaccines against Helicobacter pylori. Because children are a target group for human vaccination and Th17/Treg cells have intrinsically linked and antagonic commitments, we compared the gastric levels of Th17- and Treg-associated cytokines of children and adults. IL-6, IL-10 and TGF-β1 levels and Foxp3+ cell numbers were higher, but IL-1β, IL-17A and IL-23 were lower in infected children than in infected adults. In conclusion Treg instead of Th17 cell response to H. pylori-infection predominates in children.Helicobacter pyloriTh17TregChildrenAdultsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINAL. A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children.pdf. 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dc.title.pt_BR.fl_str_mv A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
title A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
spellingShingle A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
Melo, Fabrício Freire de
Helicobacter pylori
Th17
Treg
Children
Adults
title_short A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
title_full A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
title_fullStr A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
title_full_unstemmed A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
title_sort A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children
author Melo, Fabrício Freire de
author_facet Melo, Fabrício Freire de
Rocha, Andreia Maria Camargos
Rocha, Gifone Aguiar
Pedroso, Silvia Helena Sousa Pietra
Batista, Sérgio de Assis
Castro, Lúcia Porto Fonseca de
Carvalho, Simone Diniz
Bittencourt, Paulo Fernando Souto
Oliveira, Celso Afonso de
Oliveira, Rodrigo Corrêa de
Queiroz, Dulciene Maria de Magalhães
author_role author
author2 Rocha, Andreia Maria Camargos
Rocha, Gifone Aguiar
Pedroso, Silvia Helena Sousa Pietra
Batista, Sérgio de Assis
Castro, Lúcia Porto Fonseca de
Carvalho, Simone Diniz
Bittencourt, Paulo Fernando Souto
Oliveira, Celso Afonso de
Oliveira, Rodrigo Corrêa de
Queiroz, Dulciene Maria de Magalhães
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo, Fabrício Freire de
Rocha, Andreia Maria Camargos
Rocha, Gifone Aguiar
Pedroso, Silvia Helena Sousa Pietra
Batista, Sérgio de Assis
Castro, Lúcia Porto Fonseca de
Carvalho, Simone Diniz
Bittencourt, Paulo Fernando Souto
Oliveira, Celso Afonso de
Oliveira, Rodrigo Corrêa de
Queiroz, Dulciene Maria de Magalhães
dc.subject.en.pt_BR.fl_str_mv Helicobacter pylori
Th17
Treg
Children
Adults
topic Helicobacter pylori
Th17
Treg
Children
Adults
description Universidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Pesquisas em Bacteriologia. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-06-02T14:18:17Z
dc.date.available.fl_str_mv 2014-06-02T14:18:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv MELO, Fabrício Freire de et al. A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children. Microbes and Infection. 2012, vol.14, pp. 341-347.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7748
dc.identifier.issn.none.fl_str_mv 1286-4579
dc.identifier.doi.none.fl_str_mv 10.1016/j.micinf.2011.11.008
identifier_str_mv MELO, Fabrício Freire de et al. A regulatory instead of an IL-17 T response predominates in Helicobacter pylori-associated gastritis in children. Microbes and Infection. 2012, vol.14, pp. 341-347.
1286-4579
10.1016/j.micinf.2011.11.008
url https://www.arca.fiocruz.br/handle/icict/7748
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ltda.
publisher.none.fl_str_mv Elsevier Ltda.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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