Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings

Detalhes bibliográficos
Autor(a) principal: Trotte, Marcele N. de Sousa
Data de Publicação: 2010
Outros Autores: Pinto, Luciana W., Santos, Belmira F. dos, Menezes, Rodrigo C., Tortelly, Rogerio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36957
Resumo: Universidade Federal Fluminense. Faculdade de Veterinária. Departamento de Patologia e Clínica Veterinária. Niterói, RJ, Brasil.
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spelling Trotte, Marcele N. de SousaPinto, Luciana W.Santos, Belmira F. dosMenezes, Rodrigo C.Tortelly, Rogerio2019-11-08T14:09:59Z2019-11-08T14:09:59Z2010TROTTE, Marcele N. de Sousa et al. Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings. Brazilian Journal of Veterinary Pathology, v. 3, n. 2, p. 123-126, 2010.1983-0246https://www.arca.fiocruz.br/handle/icict/36957engAssociação Brasileira de Patologia VeterináriaSpontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Fluminense. Faculdade de Veterinária. Departamento de Patologia e Clínica Veterinária. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Serviço de Anatomia Patológica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Criação de Animais de Laboratório. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Faculdade de Veterinária. Departamento de Patologia e Clínica Veterinária. Niterói, RJ, Brasil.A spontaneous adenocarcinoma occurred in one (0.22%) adult male Syrian hamster out of 443 necropsied from a breeding animal house of the state of Rio de Janeiro, Brazil. Gross inspection showed that the renal neoplasm consisted of a unilateral single white nodule of hard consistency located in the cortex, measuring 5 mm in diameter. Microscopically, the renal epithelial cells were markedly pleomorphic and presented an abundant granular eosinophilic cytoplasm. Cells were cuboidal and mainly formed trabeculae of various widths without a lumen and also formed solid areas. There were necrotic areas and three mitotic figures per 30 high-power fields. No intravascular invasion or metastasis was observed. Positive expression of vimentin and negative expression of cytokeratin 7, pan-cytokeratin and CD10 were observed in the tumor. The histopathology and immunohistochemical profile of the renal tumor suggested the diagnosis of the eosinophilic variant of adenocarcinoma, which was reported for the first time in this species.Mesocricetus auratusRenal adenocarcinomaImmunohistochemistry,Neoplasiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36957/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Trotte_Marcele_etal_INI_2010.pdfve_Trotte_Marcele_etal_INI_2010.pdfapplication/pdf1334361https://www.arca.fiocruz.br/bitstream/icict/36957/2/ve_Trotte_Marcele_etal_INI_2010.pdf802f101e6fc528a5e396ff2a14b89a0bMD52TEXTve_Trotte_Marcele_etal_INI_2010.pdf.txtve_Trotte_Marcele_etal_INI_2010.pdf.txtExtracted texttext/plain15460https://www.arca.fiocruz.br/bitstream/icict/36957/3/ve_Trotte_Marcele_etal_INI_2010.pdf.txtaac2f2a315d6541a1fa5807b2265e433MD53icict/369572019-11-09 02:00:32.197oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-11-09T05:00:32Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
title Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
spellingShingle Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
Trotte, Marcele N. de Sousa
Mesocricetus auratus
Renal adenocarcinoma
Immunohistochemistry,
Neoplasia
title_short Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
title_full Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
title_fullStr Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
title_full_unstemmed Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
title_sort Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings
author Trotte, Marcele N. de Sousa
author_facet Trotte, Marcele N. de Sousa
Pinto, Luciana W.
Santos, Belmira F. dos
Menezes, Rodrigo C.
Tortelly, Rogerio
author_role author
author2 Pinto, Luciana W.
Santos, Belmira F. dos
Menezes, Rodrigo C.
Tortelly, Rogerio
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Trotte, Marcele N. de Sousa
Pinto, Luciana W.
Santos, Belmira F. dos
Menezes, Rodrigo C.
Tortelly, Rogerio
dc.subject.en.pt_BR.fl_str_mv Mesocricetus auratus
Renal adenocarcinoma
Immunohistochemistry,
Neoplasia
topic Mesocricetus auratus
Renal adenocarcinoma
Immunohistochemistry,
Neoplasia
description Universidade Federal Fluminense. Faculdade de Veterinária. Departamento de Patologia e Clínica Veterinária. Niterói, RJ, Brasil.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2019-11-08T14:09:59Z
dc.date.available.fl_str_mv 2019-11-08T14:09:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv TROTTE, Marcele N. de Sousa et al. Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings. Brazilian Journal of Veterinary Pathology, v. 3, n. 2, p. 123-126, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36957
dc.identifier.issn.pt_BR.fl_str_mv 1983-0246
identifier_str_mv TROTTE, Marcele N. de Sousa et al. Spontaneous renal adenocarcinoma in a Syrian hamster (Mesocricetus auratus): frequency, morphological and immunohistochemical findings. Brazilian Journal of Veterinary Pathology, v. 3, n. 2, p. 123-126, 2010.
1983-0246
url https://www.arca.fiocruz.br/handle/icict/36957
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Associação Brasileira de Patologia Veterinária
publisher.none.fl_str_mv Associação Brasileira de Patologia Veterinária
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