Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium

Detalhes bibliográficos
Autor(a) principal: Gong, Jessica
Data de Publicação: 2023
Outros Autores: Harris, Katie, Lipnicki, Darren M., Costa, Erico de Castro, Costa, Maria Fernanda Furtado Lima e, Diniz, Breno S., Xiao, Shifu, Lipton, Richard B., Katz, Mindy J., Wang, Cuiling, Preux, Pierre-Marie, Guerchet, Maëlenn, Gbessemehlan, Antoine, Ritchie, Karen, Ancelin, Marie-Laure, Skoog, Ingmar, Najar, Jenna, Sterner, Therese Rydberg, Scarmeas, Nikolaos, Yannakoulia, Mary, Kosmidis, Mary H., Guaita, Antonio, Rolandi, Elena, Davin, Annalisa, Gureje, Oye, Trompet, Stella, Gussekloo, Jacobijn, Riedel-Heller, Steffi, Pabst, Alexander, Röhr, Susanne, Shahar, Suzana, Singh, Devinder Kaur Ajit, Rivan, Nurul Fatin Malek, Boxtel, Martin van, Köhler, Sebastian, Ganguli, Mary, Chang, Chung-Chou, Jacobsen, Erin, Haan, Mary, Ding, Ding, Zhao, Qianhua, Xiao, Zhenxu, Narazaki, Kenji, Chen, Tao, Chen, Sanmei, Ng, Tze Pin, Gwee, Xinyi, Numbers, Katya, Mather, Karen A., Scazufca, Marcia, Lobo, Antonio, De-la-Cámara, Concepción, Lobo, Elena, Sachdev, Perminder S., Brodaty, Henry, Hackett, Maree L., Peters, Sanne A. E., Woodward, Mark
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/57386
Resumo: The George Institute for Global Health. University of New South Wales. Sydney, Australia/The George Institute for Global Health. Imperial College London. London, UK.
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spelling Gong, JessicaHarris, KatieLipnicki, Darren M.Costa, Erico de CastroCosta, Maria Fernanda Furtado Lima eDiniz, Breno S.Xiao, ShifuLipton, Richard B.Katz, Mindy J.Wang, CuilingPreux, Pierre-MarieGuerchet, MaëlennGbessemehlan, AntoineRitchie, KarenAncelin, Marie-LaureSkoog, IngmarNajar, JennaSterner, Therese RydbergScarmeas, NikolaosYannakoulia, MaryKosmidis, Mary H.Guaita, AntonioRolandi, ElenaDavin, AnnalisaGureje, OyeTrompet, StellaGussekloo, JacobijnRiedel-Heller, SteffiPabst, AlexanderRöhr, SusanneShahar, SuzanaSingh, Devinder Kaur AjitRivan, Nurul Fatin MalekBoxtel, Martin vanKöhler, SebastianGanguli, MaryChang, Chung-ChouJacobsen, ErinHaan, MaryDing, DingZhao, QianhuaXiao, ZhenxuNarazaki, KenjiChen, TaoChen, SanmeiNg, Tze PinGwee, XinyiNumbers, KatyaMather, Karen A.Scazufca, MarciaLobo, AntonioDe-la-Cámara, ConcepciónLobo, ElenaSachdev, Perminder S.Brodaty, HenryHackett, Maree L.Peters, Sanne A. E.Woodward, Mark2023-03-15T18:05:16Z2023-03-15T18:05:16Z2023GONG, Jessica et al. Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. Alzheimers Dement, p. 1-14, 2023.1552-5260https://www.arca.fiocruz.br/handle/icict/5738610.1002/alz.12962engJohn Wiley & Sons, Ltd.Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortiuminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThe George Institute for Global Health. University of New South Wales. Sydney, Australia/The George Institute for Global Health. Imperial College London. London, UK.The George Institute for Global Health. University of New South Wales. Sydney, Australia.Centre for Healthy Brain Ageing (CHeBA). Discipline of Psychiatry and Mental Health. Faculty of Medicine and Health. UNSW Sydney, Sydney, Australia.Oswaldo Cruz Foundation. Rene Rachou Institute. Center for Studies in Public Health and Aging. Belo Horizonte, MG, Brazil.Oswaldo Cruz Foundation. Rene Rachou Institute. Center for Studies in Public Health and Aging. Belo Horizonte, MG, Brazil.UConn Center on Aging. Department of Psychiatry, School of Medicine. University of Connecticut Health Center. Farmington, CT, USA.Department of Geriatric Psychiatry. Shanghai Mental Health Centre. Shanghai Jiaotong University School of Medicine. Shanghai, China.Department of Neurology. Albert Einstein College of Medicine, Bronx. New York, USA.Department of Neurology. Albert Einstein College of Medicine, Bronx. New York, USA.Department of Epidemiology and Community Heath. Albert Einstein College of Medicine. Bronx, New York, USA.Inserm U1094. IRD U270. Univ. Limoges. CHU Limoges. EpiMaCT - Epidemiology of chronic diseases in tropical zone. Institute of Epidemiology and Tropical Neurology. OmegaHealth. Limoges, France.Inserm U1094. IRD U270. Univ. Limoges. CHU Limoges. EpiMaCT - Epidemiology of chronic diseases in tropical zone. Institute of Epidemiology and Tropical Neurology. OmegaHealth. Limoges, France.Inserm U1094. IRD U270. Univ. Limoges. CHU Limoges. EpiMaCT - Epidemiology of chronic diseases in tropical zone. Institute of Epidemiology and Tropical Neurology. OmegaHealth. Limoges, France.INM Institute for Neurosciences of Montpellier. Univ Montpellier. INSERM. Montpellier, France.INM Institute for Neurosciences of Montpellier. Univ Montpellier. INSERM. Montpellier, France.Department of Psychiatry and Neurochemistry. Center for Ageing and Health (Age Cap). University of Gothenburg. Gothenburg, Sweden.Department of Psychiatry and Neurochemistry. Center for Ageing and Health (Age Cap). University of Gothenburg. Gothenburg, Sweden.Department of Psychiatry and Neurochemistry. Center for Ageing and Health (Age Cap). University of Gothenburg. Gothenburg, Sweden.1st Department of Neurology. Aiginition Hospital. National and Kapodistrian University of Athens Medical School. Athens, Greece / Department of Neurology, Columbia University, New York, New York, USADepartment of Nutrition and Dietetics. Harokopio University. Athens, Greece.Lab of Cognitive Neuroscience. School of Psychology. Aristotle University of Thessaloniki. Thessaloniki, Greece.Golgi Cenci Foundation. Abbiategrasso, Italy.Golgi Cenci Foundation. Abbiategrasso, Italy/Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.Golgi Cenci Foundation. Abbiategrasso, Italy.WHO Collaborating Centre for Research and Training in Mental Health. Neurosciences and Substance Abuse. Department of Psychiatry. University of Ibadan. Ibadan, Nigeria.Section of Gerontology and Geriatrics. Department of Internal Medicine. Leiden University Medical Center. Leiden, the Netherlands.Section of Gerontology and Geriatrics. Department of Internal Medicine. Leiden University Medical Center. Leiden, the Netherlands/Department of Public Health and Primary Care. Leiden, the Netherlands.Institute of Social Medicine. Occupational Health and Public Health (ISAP). University of Leipzig, Leipzig. Germany.Institute of Social Medicine. Occupational Health and Public Health (ISAP). University of Leipzig, Leipzig. Germany.Institute of Social Medicine. Occupational Health and Public Health (ISAP). University of Leipzig, Leipzig. Germany.Centre for Healthy Ageing and Wellness. Universiti Kebangsaan Malaysia. Kuala Lumpur, Malaysia.Centre for Healthy Ageing and Wellness. Universiti Kebangsaan Malaysia. Kuala Lumpur, Malaysia.Centre for Healthy Ageing and Wellness. Universiti Kebangsaan Malaysia. Kuala Lumpur, Malaysia.Alzheimer Centrum Limburg. School for Mental Health and Neuroscience. Maastricht University. Maastricht, the Netherlands.Alzheimer Centrum Limburg. School for Mental Health and Neuroscience. Maastricht University. Maastricht, the Netherlands.Department of Medicine. University of Pittsburgh. Pittsburgh, PA, USA.Department of Medicine. University of Pittsburgh. Pittsburgh, PA, USA.Department of Medicine. University of Pittsburgh. Pittsburgh, PA, USA.Department of Epidemiology and Biostatistics. School of Medicine. University of California. San Francisco, CA, USA.Institute of Neurology. National Center for Neurological Disorders. National Clinical Research Center for Aging and Medicine. Huashan Hospital. Fudan University. Shanghai, China.Institute of Neurology. National Center for Neurological Disorders. National Clinical Research Center for Aging and Medicine. Huashan Hospital. Fudan University. Shanghai, China.Institute of Neurology. National Center for Neurological Disorders. National Clinical Research Center for Aging and Medicine. Huashan Hospital. Fudan University. Shanghai, China.Center for Liberal Arts. Fukuoka Institute of Technology. Fukuoka, Japan.Sports and Health Research Center. Department of Physical Education. Tongji University. Shanghai, China.Global Health Nursing. Department of Health Sciences. Graduate School of Biomedical and Health Sciences. Hiroshima University. Hiroshima, Japan.Gerontology Research Programme. Department of Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore. Queenstown, Singapore.Gerontology Research Programme. Department of Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore. Queenstown, Singapore.Centre for Healthy Brain Ageing (CHeBA). Discipline of Psychiatry and Mental Health. Faculty of Medicine and Health. UNSW Sydney, Sydney, Australia.Centre for Healthy Brain Ageing (CHeBA). Discipline of Psychiatry and Mental Health. Faculty of Medicine and Health. UNSW Sydney, Sydney, Australia.Instituto de Psiquiátria e LIM-23. Hospital da Clínicas. Faculdade de Medicina. Universidade de São Paulo. São Paulo, SP, Brazil.Department of Medicine and Psychiatry. Universidad de Zaragoza. Zaragoza, Spain/ Instituto de Investigación Sanitaria Aragón (IIS Aragón). Zaragoza, Spain/ n°33 CIBERSAM. Madrid, Spain.Department of Medicine and Psychiatry. Universidad de Zaragoza. Zaragoza, Spain / CIBERSAM. Madrid, Spain.Instituto de Investigación Sanitaria Aragón (IIS Aragón). Zaragoza, Spain / CIBERSAM. Madrid, Spain / Department of Public Health. Universidad de Zaragoza. Zaragoza, Spain.Centre for Healthy Brain Ageing (CHeBA). Discipline of Psychiatry and Mental Health. Faculty of Medicine and Health. UNSW Sydney, Sydney, Australia.Centre for Healthy Brain Ageing (CHeBA). Discipline of Psychiatry and Mental Health. Faculty of Medicine and Health. UNSW Sydney, Sydney, Australia.The George Institute for Global Health. University of New South Wales. Sydney, Australia/Faculty of Health and Wellbeing. University of Central Lancashire. Lancashire, UK.The George Institute for Global Health. University of New South Wales. Sydney, Australia / The George Institute for Global Health. Imperial College London. London, UK / Julius Center for Health Sciences and Primary Care. University Medical Center Utrecht. Utrecht University. Utrecht, the Netherlands.The George Institute for Global Health. University of New South Wales. Sydney, Australia./The George Institute for Global Health. Imperial College London. London, UK.Introduction: Sex differences in dementia risk, and risk factor (RF) associations with dementia, remain uncertain across diverse ethno-regional groups. Methods: A total of 29,850 participants (58% women) from 21 cohorts across six continents were included in an individual participant data meta-analysis. Sex-specific hazard ratios (HRs), and women-to-men ratio of hazard ratios (RHRs) for associations between RFs and all-cause dementia were derived from mixed-effect Cox models. Results: Incident dementia occurred in 2089 (66% women) participants over 4.6 years (median). Women had higher dementia risk (HR, 1.12 [1.02, 1.23]) than men, particularly in low- and lower-middle-income economies. Associations between longer education and former alcohol use with dementia risk (RHR, 1.01 [1.00, 1.03] per year, and 0.55 [0.38, 0.79], respectively) were stronger for men than women; otherwise, there were no discernible sex differences in other RFs. Discussion: Dementia risk was higher in women than men, with possible variations by country-level income settings, but most RFs appear to work similarly in women and men.Data harmonizationDementiaDiversityRisk factorsSex differenceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/57386/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSex differences in dementia risk and risk factors.pdfSex differences in dementia risk and risk factors.pdfapplication/pdf11262793https://www.arca.fiocruz.br/bitstream/icict/57386/2/Sex%20differences%20in%20dementia%20risk%20and%20risk%20factors.pdf60d7c73830212201caee703e885a334aMD52icict/573862023-11-08 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dc.title.en_US.fl_str_mv Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
title Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
spellingShingle Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
Gong, Jessica
Data harmonization
Dementia
Diversity
Risk factors
Sex difference
title_short Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
title_full Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
title_fullStr Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
title_full_unstemmed Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
title_sort Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium
author Gong, Jessica
author_facet Gong, Jessica
Harris, Katie
Lipnicki, Darren M.
Costa, Erico de Castro
Costa, Maria Fernanda Furtado Lima e
Diniz, Breno S.
Xiao, Shifu
Lipton, Richard B.
Katz, Mindy J.
Wang, Cuiling
Preux, Pierre-Marie
Guerchet, Maëlenn
Gbessemehlan, Antoine
Ritchie, Karen
Ancelin, Marie-Laure
Skoog, Ingmar
Najar, Jenna
Sterner, Therese Rydberg
Scarmeas, Nikolaos
Yannakoulia, Mary
Kosmidis, Mary H.
Guaita, Antonio
Rolandi, Elena
Davin, Annalisa
Gureje, Oye
Trompet, Stella
Gussekloo, Jacobijn
Riedel-Heller, Steffi
Pabst, Alexander
Röhr, Susanne
Shahar, Suzana
Singh, Devinder Kaur Ajit
Rivan, Nurul Fatin Malek
Boxtel, Martin van
Köhler, Sebastian
Ganguli, Mary
Chang, Chung-Chou
Jacobsen, Erin
Haan, Mary
Ding, Ding
Zhao, Qianhua
Xiao, Zhenxu
Narazaki, Kenji
Chen, Tao
Chen, Sanmei
Ng, Tze Pin
Gwee, Xinyi
Numbers, Katya
Mather, Karen A.
Scazufca, Marcia
Lobo, Antonio
De-la-Cámara, Concepción
Lobo, Elena
Sachdev, Perminder S.
Brodaty, Henry
Hackett, Maree L.
Peters, Sanne A. E.
Woodward, Mark
author_role author
author2 Harris, Katie
Lipnicki, Darren M.
Costa, Erico de Castro
Costa, Maria Fernanda Furtado Lima e
Diniz, Breno S.
Xiao, Shifu
Lipton, Richard B.
Katz, Mindy J.
Wang, Cuiling
Preux, Pierre-Marie
Guerchet, Maëlenn
Gbessemehlan, Antoine
Ritchie, Karen
Ancelin, Marie-Laure
Skoog, Ingmar
Najar, Jenna
Sterner, Therese Rydberg
Scarmeas, Nikolaos
Yannakoulia, Mary
Kosmidis, Mary H.
Guaita, Antonio
Rolandi, Elena
Davin, Annalisa
Gureje, Oye
Trompet, Stella
Gussekloo, Jacobijn
Riedel-Heller, Steffi
Pabst, Alexander
Röhr, Susanne
Shahar, Suzana
Singh, Devinder Kaur Ajit
Rivan, Nurul Fatin Malek
Boxtel, Martin van
Köhler, Sebastian
Ganguli, Mary
Chang, Chung-Chou
Jacobsen, Erin
Haan, Mary
Ding, Ding
Zhao, Qianhua
Xiao, Zhenxu
Narazaki, Kenji
Chen, Tao
Chen, Sanmei
Ng, Tze Pin
Gwee, Xinyi
Numbers, Katya
Mather, Karen A.
Scazufca, Marcia
Lobo, Antonio
De-la-Cámara, Concepción
Lobo, Elena
Sachdev, Perminder S.
Brodaty, Henry
Hackett, Maree L.
Peters, Sanne A. E.
Woodward, Mark
author2_role author
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dc.contributor.author.fl_str_mv Gong, Jessica
Harris, Katie
Lipnicki, Darren M.
Costa, Erico de Castro
Costa, Maria Fernanda Furtado Lima e
Diniz, Breno S.
Xiao, Shifu
Lipton, Richard B.
Katz, Mindy J.
Wang, Cuiling
Preux, Pierre-Marie
Guerchet, Maëlenn
Gbessemehlan, Antoine
Ritchie, Karen
Ancelin, Marie-Laure
Skoog, Ingmar
Najar, Jenna
Sterner, Therese Rydberg
Scarmeas, Nikolaos
Yannakoulia, Mary
Kosmidis, Mary H.
Guaita, Antonio
Rolandi, Elena
Davin, Annalisa
Gureje, Oye
Trompet, Stella
Gussekloo, Jacobijn
Riedel-Heller, Steffi
Pabst, Alexander
Röhr, Susanne
Shahar, Suzana
Singh, Devinder Kaur Ajit
Rivan, Nurul Fatin Malek
Boxtel, Martin van
Köhler, Sebastian
Ganguli, Mary
Chang, Chung-Chou
Jacobsen, Erin
Haan, Mary
Ding, Ding
Zhao, Qianhua
Xiao, Zhenxu
Narazaki, Kenji
Chen, Tao
Chen, Sanmei
Ng, Tze Pin
Gwee, Xinyi
Numbers, Katya
Mather, Karen A.
Scazufca, Marcia
Lobo, Antonio
De-la-Cámara, Concepción
Lobo, Elena
Sachdev, Perminder S.
Brodaty, Henry
Hackett, Maree L.
Peters, Sanne A. E.
Woodward, Mark
dc.subject.en.en_US.fl_str_mv Data harmonization
Dementia
Diversity
Risk factors
Sex difference
topic Data harmonization
Dementia
Diversity
Risk factors
Sex difference
description The George Institute for Global Health. University of New South Wales. Sydney, Australia/The George Institute for Global Health. Imperial College London. London, UK.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-03-15T18:05:16Z
dc.date.available.fl_str_mv 2023-03-15T18:05:16Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GONG, Jessica et al. Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. Alzheimers Dement, p. 1-14, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/57386
dc.identifier.issn.en_US.fl_str_mv 1552-5260
dc.identifier.doi.none.fl_str_mv 10.1002/alz.12962
identifier_str_mv GONG, Jessica et al. Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. Alzheimers Dement, p. 1-14, 2023.
1552-5260
10.1002/alz.12962
url https://www.arca.fiocruz.br/handle/icict/57386
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Wiley & Sons, Ltd.
publisher.none.fl_str_mv John Wiley & Sons, Ltd.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/57386/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/57386/2/Sex%20differences%20in%20dementia%20risk%20and%20risk%20factors.pdf
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
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bitstream.checksumAlgorithm.fl_str_mv MD5
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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