Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Detalhes bibliográficos
Autor(a) principal: Facchinetti, L. D.
Data de Publicação: 2013
Outros Autores: Araújo, A. Q. C., Chequer, G. L., Azevedo, M. F. de, Oliveira, R. V. C., Lima, M. A. S. D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/33738
Resumo: 2019-12-28
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spelling Facchinetti, L. D.Araújo, A. Q. C.Chequer, G. L.Azevedo, M. F. deOliveira, R. V. C.Lima, M. A. S. D.2019-06-30T18:07:59Z2019-06-30T18:07:59Z2013FACCHINETTI, L. D. et al. Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), v. 51, p. 222-225, 2013.1362-4393https://www.arca.fiocruz.br/handle/icict/3373810.1038/sc.2012.1341476-5624engSpringer NatureFalls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2019-12-28Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecções. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecções. Rio de Janeiro, RJ, Brasil.Study design: Cross-sectional study. Objectives: To determine the prevalence of falls in human T-cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and possible factors associated to their occurrence. Setting: Instituto de Pesquisa Clı´nica Evandro Chagas, Fundac¸a˜o Oswaldo Cruz (FIOCRUZ) - Brazil. Methods: Thirty-six HAM/TSP patients able to walk at least 20 m were assessed by a questionnaire. Data regarding gender, age, duration of disease (DD), HTLV-I proviral load (HPL), frequency of physical activity (FCA), use of walking aids, functional ambulation level, the number of falls and associated injuries in the last year were reviewed. Multiple correspondence analysis was used to group characteristics of this sample according to the fall occurrence. Results: The prevalence of falls was 63.9% and we observed injuries in 47.8% of the cases. Four groups were identified in the descriptive analysis. One group was formed by faller individuals, men < 60 years, independent ambulation, FCA ≥ 3 times per week and HPL < 6.6 copies per 100 cells (group B). The other one comprised non-faller patients, women < 60 years, restricted ambulation, DD ≥ 7 years, use of orthosis, FCA 0-1 time per week and HPL ≥ 6.6 copies per 100 cells (group D). The others two groups comprised individuals that did not use orthosis (group A) and those that FCA was two times per week and DD < 7 years (group C). Conclusion: Falls occur in roughly two-thirds of ambulatory HAM/TSP patients and are associated with significant morbidity. Further studies with a larger number of patients are necessarily to identify risk factors in order to elaborate specific programs to prevent falls in this population.HTLV-I-associated myelopathyTropical spastic paraparesisFall riskinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33738/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Facchinetti_LD_etal_INI_2013.pdfve_Facchinetti_LD_etal_INI_2013.pdfapplication/pdf294493https://www.arca.fiocruz.br/bitstream/icict/33738/2/ve_Facchinetti_LD_etal_INI_2013.pdf73541145ba2cc9839385cacfd5f3a6aaMD52TEXTve_Facchinetti_LD_etal_INI_2013.pdf.txtve_Facchinetti_LD_etal_INI_2013.pdf.txtExtracted texttext/plain20392https://www.arca.fiocruz.br/bitstream/icict/33738/3/ve_Facchinetti_LD_etal_INI_2013.pdf.txt7f9666082a07f4886ae36382c394ae7cMD53icict/337382021-03-24 16:32:25.925oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:25Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
title Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
spellingShingle Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Facchinetti, L. D.
HTLV-I-associated myelopathy
Tropical spastic paraparesis
Fall risk
title_short Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
title_full Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
title_fullStr Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
title_full_unstemmed Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
title_sort Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
author Facchinetti, L. D.
author_facet Facchinetti, L. D.
Araújo, A. Q. C.
Chequer, G. L.
Azevedo, M. F. de
Oliveira, R. V. C.
Lima, M. A. S. D.
author_role author
author2 Araújo, A. Q. C.
Chequer, G. L.
Azevedo, M. F. de
Oliveira, R. V. C.
Lima, M. A. S. D.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Facchinetti, L. D.
Araújo, A. Q. C.
Chequer, G. L.
Azevedo, M. F. de
Oliveira, R. V. C.
Lima, M. A. S. D.
dc.subject.en.pt_BR.fl_str_mv HTLV-I-associated myelopathy
Tropical spastic paraparesis
Fall risk
topic HTLV-I-associated myelopathy
Tropical spastic paraparesis
Fall risk
description 2019-12-28
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2019-06-30T18:07:59Z
dc.date.available.fl_str_mv 2019-06-30T18:07:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FACCHINETTI, L. D. et al. Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), v. 51, p. 222-225, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33738
dc.identifier.issn.pt_BR.fl_str_mv 1362-4393
dc.identifier.doi.none.fl_str_mv 10.1038/sc.2012.134
dc.identifier.eissn.none.fl_str_mv 1476-5624
identifier_str_mv FACCHINETTI, L. D. et al. Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), v. 51, p. 222-225, 2013.
1362-4393
10.1038/sc.2012.134
1476-5624
url https://www.arca.fiocruz.br/handle/icict/33738
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/33738/1/license.txt
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