Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/58074 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. |
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Arantes, IghorBello, GonzaloNascimento, ValdineteSouza, VictorSilva, Arlesson daSilva, DejananeNascimento, FernandaMejia, MatildeBrandão, Maria JúliaGonçalves, LucianaSilva, GeorgeCosta, Cristiano Fernandes daAbdalla, Lígia FernandesSantos, João HugoRamos, Tatyana Costa AmorimPiantham, ChayadaIto, KimihitoSiqueira, Marilda MendonçaResende, Paola CristinaWallau, Gabriel LuzDelatorre, EdsonGräf, TiagoNaveca, Felipe Gomes2023-04-28T20:21:17Z2023-04-28T20:21:17Z2023ARANTES, Ighor et al. Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas. Nature Communications, v.14: 2048, p. 1 - 15, Apr. 2023.2041-1723https://www.arca.fiocruz.br/handle/icict/5807410.1038/s41467-023-37541-6engNature CommunicationsEstado brasileiro do AmazonasExpansão epidêmica comparativaVariantes SARS-CoV-2 Delta e OmicronComparative epidemic expansionSARS-CoV-2 variants Delta and OmicronBrazilian State of AmazonasComparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil / Fundação de Vigilância em Saúde do Amazonas - Dra Rosemary Costa Pinto, Manaus, AM, Brasil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil / Fundação Centro de Controle de Oncologia do Estado do Amazonas. Manaus, AM, Brasil.Fundação de Vigilância em Saúde do Amazonas - Dra Rosemary Costa Pinto. Manaus, AM. Brasil / Conselho de Secretários Municipais de Saúde do Amazonas. AM, Brasil.Universidade do Estado do Amazonas. Manaus, Brasil.Hospital Adventista de Manaus, Manaus, AM, Brasil.Fundação de Vigilância em Saúde do Amazonas - Dra Rosemary Costa Pinto. Manaus, AM, Brasil.Graduate School of Infectious Diseases, Hokkaido University, Hokkaido. Japan.International Institute for Zoonosis Control, Hokkaido University. Hokkaido, Japan.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto AggeuMagalhães. Recife, PE, Brasil / Department of Arbovirology, Bernhard Nocht Institute for TropicalMedicine. Hamburg,Germany.Universidade Federal do Espírito Santo. Centro deCiências Exatas, Naturais e da Saúde. Departamento de Biologia. Centro deCiências Exatas, Naturais e da Saúde. Alegre, ES, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil.Instituto Leônidas e Maria Deane, Fiocruz, Laboratório de Ecologia de Doenças Transmissíveis na Amazônia. Manaus, Brazil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Arbovírus e Vírus Hemorrágicos. Rio de Janeiro, RJ, BrasilThe SARS-CoV-2 variants of concern (VOCs) Delta and Omicron spread globally during mid and late 2021, respectively. In this study, we compare the dissemination dynamics of these VOCs in the Amazonas state, one of Brazil’s most heavily affected regions. We sequenced the virus genome from 4128 patients collected in Amazonas between July 1st, 2021, and January 31st, 2022, and investigated the viral dynamics using a phylodynamic approach. The VOCs Delta and Omicron BA.1 displayed similar patterns of phylogeographic spread but different epidemic dynamics. The replacement of Gamma by Delta was gradual and occurred without an upsurge of COVID-19 cases, while the rise of Omicron BA.1was extremely fast and fueled a sharp increase in cases. Thus, the dissemination dynamics and population-level impact of new SARS-CoV-2 variants introduced in the Amazonian population after mid-2021, a setting with high levels of acquired immunity, greatly vary according to their viral phenotype.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/58074/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALIgorArantes_TiagoNaveca_etal_IOC_2023.pdfIgorArantes_TiagoNaveca_etal_IOC_2023.pdfapplication/pdf3034949https://www.arca.fiocruz.br/bitstream/icict/58074/2/IgorArantes_TiagoNaveca_etal_IOC_2023.pdfb1d1f9bd9879fe6cd16ec7c33ae85bdeMD52icict/580742023-09-14 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| dc.title.en_US.fl_str_mv |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| title |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| spellingShingle |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas Arantes, Ighor Estado brasileiro do Amazonas Expansão epidêmica comparativa Variantes SARS-CoV-2 Delta e Omicron Comparative epidemic expansion SARS-CoV-2 variants Delta and Omicron Brazilian State of Amazonas |
| title_short |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| title_full |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| title_fullStr |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| title_full_unstemmed |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| title_sort |
Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas |
| author |
Arantes, Ighor |
| author_facet |
Arantes, Ighor Bello, Gonzalo Nascimento, Valdinete Souza, Victor Silva, Arlesson da Silva, Dejanane Nascimento, Fernanda Mejia, Matilde Brandão, Maria Júlia Gonçalves, Luciana Silva, George Costa, Cristiano Fernandes da Abdalla, Lígia Fernandes Santos, João Hugo Ramos, Tatyana Costa Amorim Piantham, Chayada Ito, Kimihito Siqueira, Marilda Mendonça Resende, Paola Cristina Wallau, Gabriel Luz Delatorre, Edson Gräf, Tiago Naveca, Felipe Gomes |
| author_role |
author |
| author2 |
Bello, Gonzalo Nascimento, Valdinete Souza, Victor Silva, Arlesson da Silva, Dejanane Nascimento, Fernanda Mejia, Matilde Brandão, Maria Júlia Gonçalves, Luciana Silva, George Costa, Cristiano Fernandes da Abdalla, Lígia Fernandes Santos, João Hugo Ramos, Tatyana Costa Amorim Piantham, Chayada Ito, Kimihito Siqueira, Marilda Mendonça Resende, Paola Cristina Wallau, Gabriel Luz Delatorre, Edson Gräf, Tiago Naveca, Felipe Gomes |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Arantes, Ighor Bello, Gonzalo Nascimento, Valdinete Souza, Victor Silva, Arlesson da Silva, Dejanane Nascimento, Fernanda Mejia, Matilde Brandão, Maria Júlia Gonçalves, Luciana Silva, George Costa, Cristiano Fernandes da Abdalla, Lígia Fernandes Santos, João Hugo Ramos, Tatyana Costa Amorim Piantham, Chayada Ito, Kimihito Siqueira, Marilda Mendonça Resende, Paola Cristina Wallau, Gabriel Luz Delatorre, Edson Gräf, Tiago Naveca, Felipe Gomes |
| dc.subject.other.en_US.fl_str_mv |
Estado brasileiro do Amazonas Expansão epidêmica comparativa Variantes SARS-CoV-2 Delta e Omicron |
| topic |
Estado brasileiro do Amazonas Expansão epidêmica comparativa Variantes SARS-CoV-2 Delta e Omicron Comparative epidemic expansion SARS-CoV-2 variants Delta and Omicron Brazilian State of Amazonas |
| dc.subject.en.en_US.fl_str_mv |
Comparative epidemic expansion SARS-CoV-2 variants Delta and Omicron Brazilian State of Amazonas |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. |
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2023 |
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2023-04-28T20:21:17Z |
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2023-04-28T20:21:17Z |
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2023 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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ARANTES, Ighor et al. Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas. Nature Communications, v.14: 2048, p. 1 - 15, Apr. 2023. |
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https://www.arca.fiocruz.br/handle/icict/58074 |
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2041-1723 |
| dc.identifier.doi.none.fl_str_mv |
10.1038/s41467-023-37541-6 |
| identifier_str_mv |
ARANTES, Ighor et al. Comparative epidemic expansion of SARS-CoV-2 variants Delta and Omicron in the Brazilian State of Amazonas. Nature Communications, v.14: 2048, p. 1 - 15, Apr. 2023. 2041-1723 10.1038/s41467-023-37541-6 |
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Nature Communications |
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Nature Communications |
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