Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/9341 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, Brasil /Universidade Federal de Minas Gerais. Departamento de Morfologia. Belo Horizonte, MG, Brasil/Fundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil |
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Silva, Luciana MariaDias, Consuelo Latorre FortesSchaffert, Priscila PereiraBotelho, Ana Cristina CarvalhoPimenta, Rafael NacifCosta, Maria Inácia EstevãoCordeiro, Marta do NascimentoPimenta, Paulo Filemon Paolucci2015-01-07T16:09:20Z2015-01-07T16:09:20Z2011SILVA, Luciana Maria et al. Developmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891): microanatomical and molecular analysis of the embryonic stages. Toxicon, vol. 57, n. 1, pp. 19-27, 2011.0041-0101https://www.arca.fiocruz.br/handle/icict/934110.1016/j.toxicon.2010.09.006engElsevier LtdaDevelopmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stagesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, Brasil /Universidade Federal de Minas Gerais. Departamento de Morfologia. Belo Horizonte, MG, Brasil/Fundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, BrasilFundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, BrasilFundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, Brasil/Universidade de Montes Claros. Montes Claros, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, BrasilFundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, BrasilFundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, Brasil/Universidade Federal de Minas Gerais. Departamento de Morfologia. Belo Horizonte, MG, BrasilPhoneutria (Ctenidae) is among the most dangerous venomous spiders in Brazil. Its venom is composed of a mixture of pharmacologically active components, some of which have been quite extensively studied due to their potentiality as models for new pharmaceutical drugs. Nevertheless, literature data on the venom-producing glands are very limited. In the present study, we follow the biological development of intra-cocoon stages of Phoneutria nigriventer spiders, mainly regarding the formation of the venomous apparatus and venom production. The results showed that the venom glands of Phoneutria are already present in the early 1st pre-larva stage. The venomous apparatus is completely formed in the larva, a stage that precedes the spider eclosion from the cocoon. At embryo stages, transcripts of a vertebrate-active neurotoxin (PhTx1) were shown to be present, as well as, unidentified venom proteins that were immunolabeled by anti-venom antibodies. It seems that venom toxins play roles in the protection and survival of those early developmental stages of Phoneutria spiders.Phoneutria nigriventerArmed spiderDevelopmental biologyVenom glandSpider toxininfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/9341/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALDevelopmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891).pdfDevelopmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891).pdfapplication/pdf1650087https://www.arca.fiocruz.br/bitstream/icict/9341/2/Developmental%20biology%20of%20the%20Brazilian%20Armed%20spider%20Phoneutria%20nigriventer%20%28Keyserling%2c%201891%29.pdf8b1cd36df9ed709b2f1716264889b9b2MD52TEXTDevelopmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891).pdf.txtDevelopmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891).pdf.txtExtracted texttext/plain33723https://www.arca.fiocruz.br/bitstream/icict/9341/3/Developmental%20biology%20of%20the%20Brazilian%20Armed%20spider%20Phoneutria%20nigriventer%20%28Keyserling%2c%201891%29.pdf.txt80abb02ccd7c61d02e14b229fcc65932MD53icict/93412019-06-19 10:06:38.19oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-06-19T13:06:38Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| title |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| spellingShingle |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages Silva, Luciana Maria Phoneutria nigriventer Armed spider Developmental biology Venom gland Spider toxin |
| title_short |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| title_full |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| title_fullStr |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| title_full_unstemmed |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| title_sort |
Developmental biology of the Brazilian ‘Armed’ spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages |
| author |
Silva, Luciana Maria |
| author_facet |
Silva, Luciana Maria Dias, Consuelo Latorre Fortes Schaffert, Priscila Pereira Botelho, Ana Cristina Carvalho Pimenta, Rafael Nacif Costa, Maria Inácia Estevão Cordeiro, Marta do Nascimento Pimenta, Paulo Filemon Paolucci |
| author_role |
author |
| author2 |
Dias, Consuelo Latorre Fortes Schaffert, Priscila Pereira Botelho, Ana Cristina Carvalho Pimenta, Rafael Nacif Costa, Maria Inácia Estevão Cordeiro, Marta do Nascimento Pimenta, Paulo Filemon Paolucci |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Luciana Maria Dias, Consuelo Latorre Fortes Schaffert, Priscila Pereira Botelho, Ana Cristina Carvalho Pimenta, Rafael Nacif Costa, Maria Inácia Estevão Cordeiro, Marta do Nascimento Pimenta, Paulo Filemon Paolucci |
| dc.subject.en.pt_BR.fl_str_mv |
Phoneutria nigriventer Armed spider Developmental biology Venom gland Spider toxin |
| topic |
Phoneutria nigriventer Armed spider Developmental biology Venom gland Spider toxin |
| description |
Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Entomologia médica. Belo Horizonte, MG, Brasil /Universidade Federal de Minas Gerais. Departamento de Morfologia. Belo Horizonte, MG, Brasil/Fundação Ezequiel Dias. Centro de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil |
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2011 |
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2011 |
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2015-01-07T16:09:20Z |
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2015-01-07T16:09:20Z |
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info:eu-repo/semantics/article |
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| dc.identifier.citation.fl_str_mv |
SILVA, Luciana Maria et al. Developmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891): microanatomical and molecular analysis of the embryonic stages. Toxicon, vol. 57, n. 1, pp. 19-27, 2011. |
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https://www.arca.fiocruz.br/handle/icict/9341 |
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0041-0101 |
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10.1016/j.toxicon.2010.09.006 |
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SILVA, Luciana Maria et al. Developmental biology of the Brazilian Armed spider Phoneutria nigriventer (Keyserling, 1891): microanatomical and molecular analysis of the embryonic stages. Toxicon, vol. 57, n. 1, pp. 19-27, 2011. 0041-0101 10.1016/j.toxicon.2010.09.006 |
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