The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review

Detalhes bibliográficos
Autor(a) principal: Suffys, Philip N.
Data de Publicação: 1997
Outros Autores: Araujo, Marcelo E. Ivens de, Degrave, Wim M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36814
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Biologia Molecular e Diagnóstico de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.
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spelling Suffys, Philip N.Araujo, Marcelo E. Ivens deDegrave, Wim M.2019-11-02T20:05:03Z2019-11-02T20:05:03Z1997SUFFYS, Philip N.; ARAUJO, Marcel E. Ivens de; DEGRAVE, Wim M. The Changing Face of the Epidemiology of Tuberculosis due to Molecular Strain Typing - A Review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 3, p. 297-316, May/June 1997.0074-0276https://www.arca.fiocruz.br/handle/icict/3681410.1590/s0074-027619970003000011678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.TuberculoseEpidemiologia molecularImpressões digitaisPolimorfismo do comprimento do fragmento da limitaçãoTuberculosisMolecular epidemiologyFingerprintingRestriction fragment length polymorphismThe changing face of the epidemiology of tuberculosis due to molecular strain typing--a reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Biologia Molecular e Diagnóstico de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Biologia Molecular e Diagnóstico de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Biologia Molecular e Diagnóstico de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.About one third of the world population is infected with tubercle bacilli, causing eight million new cases of tuberculosis (TB) and three million deaths each year. After years of lack of interest in the disease, World Health Organization recently declared TB a global emergency and it is clear that there is need for more efficient national TB programs and newly defined research priorities. A more complete epidemiology of tuberculosis will lead to a better identification of index cases and to a more efficient treatment of the disease. Recently, new molecular tools became available for the identification of strains of Mycobacterium tuberculosis (M. tuberculosis), allowing a better recognition of transmission routes of defined strains. Both a standardized restriction-fragment-length-polymorphism-based methodology for epidemiological studies on a large scale and deoxyribonucleic acids (DNA) amplification-based methods that allow rapid detection of outbreaks with multidrug-resistant (MDR) strains, often characterized by high mortality rates, have been developed. This review comments on the existing methods of DNA-based recognition of M. tuberculosis strains and their peculiarities. It also summarizes literature data on the application of molecular fingerprinting for detection of outbreaks of M. tuberculosis, for identification of index cases, for study of interaction between TB and infection with the human immuno-deficiency virus, for analysis of the behavior of MDR strains, for a better understanding of risk factors for transmission of TB within communities and for population-based studies of TB transmission within and between countries.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
title The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
spellingShingle The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
Suffys, Philip N.
Tuberculose
Epidemiologia molecular
Impressões digitais
Polimorfismo do comprimento do fragmento da limitação
Tuberculosis
Molecular epidemiology
Fingerprinting
Restriction fragment length polymorphism
title_short The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
title_full The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
title_fullStr The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
title_full_unstemmed The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
title_sort The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review
author Suffys, Philip N.
author_facet Suffys, Philip N.
Araujo, Marcelo E. Ivens de
Degrave, Wim M.
author_role author
author2 Araujo, Marcelo E. Ivens de
Degrave, Wim M.
author2_role author
author
dc.contributor.author.fl_str_mv Suffys, Philip N.
Araujo, Marcelo E. Ivens de
Degrave, Wim M.
dc.subject.other.pt_BR.fl_str_mv Tuberculose
Epidemiologia molecular
Impressões digitais
Polimorfismo do comprimento do fragmento da limitação
topic Tuberculose
Epidemiologia molecular
Impressões digitais
Polimorfismo do comprimento do fragmento da limitação
Tuberculosis
Molecular epidemiology
Fingerprinting
Restriction fragment length polymorphism
dc.subject.en.pt_BR.fl_str_mv Tuberculosis
Molecular epidemiology
Fingerprinting
Restriction fragment length polymorphism
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Biologia Molecular e Diagnóstico de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.
publishDate 1997
dc.date.issued.fl_str_mv 1997
dc.date.accessioned.fl_str_mv 2019-11-02T20:05:03Z
dc.date.available.fl_str_mv 2019-11-02T20:05:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SUFFYS, Philip N.; ARAUJO, Marcel E. Ivens de; DEGRAVE, Wim M. The Changing Face of the Epidemiology of Tuberculosis due to Molecular Strain Typing - A Review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 3, p. 297-316, May/June 1997.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36814
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/s0074-02761997000300001
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv SUFFYS, Philip N.; ARAUJO, Marcel E. Ivens de; DEGRAVE, Wim M. The Changing Face of the Epidemiology of Tuberculosis due to Molecular Strain Typing - A Review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 3, p. 297-316, May/June 1997.
0074-0276
10.1590/s0074-02761997000300001
1678-8060
url https://www.arca.fiocruz.br/handle/icict/36814
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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