Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/19358 |
Resumo: | Marilda de Souza Gonçalves “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Castro, Vagner deOriga, Andréa FernandaBizzacchi, Joyce Maria AnnichinoSoares, Manoel do Carmo PereiraMenezes, R. CGonçalves, Marilda de SouzaCosta, Fernando FerreiraArruda, Valder Roberval2017-06-09T16:30:08Z2017-06-09T16:30:08Z1999CASTRO, V. et al. Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil. European Journal of Immunogenetics, v. 26, p. 355-360, 1999.0960-7420https://www.arca.fiocruz.br/handle/icict/19358Marilda de Souza Gonçalves “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, BrasilState University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, BrasilState University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, BrasilEvandro Chagas Institute. Belém, PA, BrasilEvandro Chagas Institute. Belém, PA, BrasilUniversidade Federal da Bahia. Salvador, BA, BrasilState University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, BrasilState University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, BrasilThe human platelet antigen (HPA) systems are related to immune platelet disorders as well as to the development of occlusive vascular disease. Several distinct biallelic HPA systems are known, and a heterogeneous distribution of HPA alleles has been described among distinct ethnic groups. In this study we genotyped 320 carefully selected individuals from three distinct ethnic groups in Brazil (Caucasians, Blacks and Amazonian Indians) for the HPA-1, -2, -3, -4 and -5 systems. A similar prevalence for all HPA alleles was found in Brazilians of Caucasian and Black descent. These data contrast with those reported for similar ethnic groups in other countries. Among the Amazonian Indians, no b allele of the HPA- 1, -4 and -5 systems was identified. The data presented here could be useful in the diagnosis of alloimmune platelet disease, in genetic counselling and in the development of screening programmes for HPA-related diseasesengBlackwell SciencePlaquetasDoença VascularGrupos etnicosAlelosBrasilPlateletOcclusive vascularEthnic groupsAllelesBrazilPlaquetasDoença VascularGrupos etnicosAlelosBrazilFrequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19358/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCastro V Frequencies of platelet....pdfCastro V Frequencies of 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14:34:04.918oai:www.arca.fiocruz.br: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ório 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dc.title.pt_BR.fl_str_mv |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
title |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
spellingShingle |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil Castro, Vagner de Plaquetas Doença Vascular Grupos etnicos Alelos Brasil Platelet Occlusive vascular Ethnic groups Alleles Brazil Plaquetas Doença Vascular Grupos etnicos Alelos Brazil |
title_short |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
title_full |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
title_fullStr |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
title_full_unstemmed |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
title_sort |
Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil |
author |
Castro, Vagner de |
author_facet |
Castro, Vagner de Origa, Andréa Fernanda Bizzacchi, Joyce Maria Annichino Soares, Manoel do Carmo Pereira Menezes, R. C Gonçalves, Marilda de Souza Costa, Fernando Ferreira Arruda, Valder Roberval |
author_role |
author |
author2 |
Origa, Andréa Fernanda Bizzacchi, Joyce Maria Annichino Soares, Manoel do Carmo Pereira Menezes, R. C Gonçalves, Marilda de Souza Costa, Fernando Ferreira Arruda, Valder Roberval |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Castro, Vagner de Origa, Andréa Fernanda Bizzacchi, Joyce Maria Annichino Soares, Manoel do Carmo Pereira Menezes, R. C Gonçalves, Marilda de Souza Costa, Fernando Ferreira Arruda, Valder Roberval |
dc.subject.other.pt_BR.fl_str_mv |
Plaquetas Doença Vascular Grupos etnicos Alelos Brasil |
topic |
Plaquetas Doença Vascular Grupos etnicos Alelos Brasil Platelet Occlusive vascular Ethnic groups Alleles Brazil Plaquetas Doença Vascular Grupos etnicos Alelos Brazil |
dc.subject.en.pt_BR.fl_str_mv |
Platelet Occlusive vascular Ethnic groups Alleles Brazil |
dc.subject.decs.pt_BR.fl_str_mv |
Plaquetas Doença Vascular Grupos etnicos Alelos Brazil |
description |
Marilda de Souza Gonçalves “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
publishDate |
1999 |
dc.date.issued.fl_str_mv |
1999 |
dc.date.accessioned.fl_str_mv |
2017-06-09T16:30:08Z |
dc.date.available.fl_str_mv |
2017-06-09T16:30:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CASTRO, V. et al. Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil. European Journal of Immunogenetics, v. 26, p. 355-360, 1999. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/19358 |
dc.identifier.issn.pt_BR.fl_str_mv |
0960-7420 |
identifier_str_mv |
CASTRO, V. et al. Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil. European Journal of Immunogenetics, v. 26, p. 355-360, 1999. 0960-7420 |
url |
https://www.arca.fiocruz.br/handle/icict/19358 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Blackwell Science |
publisher.none.fl_str_mv |
Blackwell Science |
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