Intensive care management of patients with COVID‑19: a practical approach
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/46374 |
Resumo: | University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil. |
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Hajjar, Ludhmila AbrahãoCosta, Isabela Bispo Santos da SilvaKalil Filho, RobertoRizk, Stephanie ItalaBiselli, BrunoGomes, Bruno RizerioLacerda, Marcus ViniciusLeme, Alcino CostaLopes, Marcela de Almeida2021-03-17T19:02:19Z2021-03-17T19:02:19Z2021HAJJAR, Ludhmila Abrahão al. Intensive care management of patients with COVID-19: a practical approach. Annals of Intensive Care, Heidelberg, v. 11, p. 1-17, Feb. 2021.2110-5820https://www.arca.fiocruz.br/handle/icict/4637410.1186/s13613-021-00820-w2110-58202110-5820engJean-Louis Teboul, CHU Bicêtre, FranceIntensive care management of patients with COVID‑19: a practical approachinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.University of São Paulo. Instituto do Câncer. São Paulo, SP, Brazil.University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisas Leônidas e Maria Deane. Manaus, AM, Brazil.University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil.Hospital da Cidade. Salvador, BA, Brazil.SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is responsible for the largest pandemic facing humanity since the Spanish flu pandemic in the early twentieth century. Since there is no specific antiviral treatment, optimized support is the most relevant factor in the patient's prognosis. In the hospital setting, the identification of high-risk patients for clinical deterioration is essential to ensure access to intensive treatment of severe conditions in a timely manner. The initial management of hypoxemia includes conventional oxygen therapy, high-flow nasal canula oxygen, and non-invasive ventilation. For patients requiring invasive mechanical ventilation, lung-protective ventilation with low tidal volumes and plateau pressure is recommended. Cardiovascular complications are frequent and include myocardial injury, thrombotic events, myocarditis, and cardiogenic shock. Acute renal failure is a common complication and is a marker of poor prognosis, with significant impact in costs and resources allocation. Regarding promising therapies for COVID-19, the most promising drugs until now are remdesivir and corticosteroids although further studies may be needed to confirm their effectiveness. Other therapies such as, tocilizumab, anakinra, other anti-cytokine drugs, and heparin are being tested in clinical trials. Thousands of physicians are living a scenario that none of us have ever seen: demand for hospital exceed capacity in most countries. Until now, the certainty we have is that we should try to decrease the number of infected patients and that an optimized critical care support is the best strategy to improve patient’s survival.COVID-19Intensive care unitCirculatory support and invasive ventilationinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/46374/1/license.txt43cf57123dace9a28c9f6b2c996fa81bMD51ORIGINALArticle 2021 Intensive care management of patients with Covid19.pdfArticle 2021 Intensive care management of patients with Covid19.pdfapplication/pdf2032581https://www.arca.fiocruz.br/bitstream/icict/46374/2/Article%202021%20Intensive%20care%20management%20of%20patients%20with%20Covid19.pdf2a641488a42dbab540e145a5c87a8e51MD52TEXTArticle 2021 Intensive care management of patients with Covid19.pdf.txtArticle 2021 Intensive care management of patients with Covid19.pdf.txtExtracted texttext/plain85212https://www.arca.fiocruz.br/bitstream/icict/46374/3/Article%202021%20Intensive%20care%20management%20of%20patients%20with%20Covid19.pdf.txtc11512eec3d16518629044b51e2433e6MD53icict/463742021-03-18 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dc.title.pt_BR.fl_str_mv |
Intensive care management of patients with COVID‑19: a practical approach |
title |
Intensive care management of patients with COVID‑19: a practical approach |
spellingShingle |
Intensive care management of patients with COVID‑19: a practical approach Hajjar, Ludhmila Abrahão COVID-19 Intensive care unit Circulatory support and invasive ventilation |
title_short |
Intensive care management of patients with COVID‑19: a practical approach |
title_full |
Intensive care management of patients with COVID‑19: a practical approach |
title_fullStr |
Intensive care management of patients with COVID‑19: a practical approach |
title_full_unstemmed |
Intensive care management of patients with COVID‑19: a practical approach |
title_sort |
Intensive care management of patients with COVID‑19: a practical approach |
author |
Hajjar, Ludhmila Abrahão |
author_facet |
Hajjar, Ludhmila Abrahão Costa, Isabela Bispo Santos da Silva Kalil Filho, Roberto Rizk, Stephanie Itala Biselli, Bruno Gomes, Bruno Rizerio Lacerda, Marcus Vinicius Leme, Alcino Costa Lopes, Marcela de Almeida |
author_role |
author |
author2 |
Costa, Isabela Bispo Santos da Silva Kalil Filho, Roberto Rizk, Stephanie Itala Biselli, Bruno Gomes, Bruno Rizerio Lacerda, Marcus Vinicius Leme, Alcino Costa Lopes, Marcela de Almeida |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Hajjar, Ludhmila Abrahão Costa, Isabela Bispo Santos da Silva Kalil Filho, Roberto Rizk, Stephanie Itala Biselli, Bruno Gomes, Bruno Rizerio Lacerda, Marcus Vinicius Leme, Alcino Costa Lopes, Marcela de Almeida |
dc.subject.en.pt_BR.fl_str_mv |
COVID-19 Intensive care unit Circulatory support and invasive ventilation |
topic |
COVID-19 Intensive care unit Circulatory support and invasive ventilation |
description |
University of São Paulo Medical School. Instituto do Coração. São Paulo, SP, Brazil. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-03-17T19:02:19Z |
dc.date.available.fl_str_mv |
2021-03-17T19:02:19Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
HAJJAR, Ludhmila Abrahão al. Intensive care management of patients with COVID-19: a practical approach. Annals of Intensive Care, Heidelberg, v. 11, p. 1-17, Feb. 2021. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/46374 |
dc.identifier.issn.pt_BR.fl_str_mv |
2110-5820 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1186/s13613-021-00820-w |
dc.identifier.eissn.none.fl_str_mv |
2110-5820 2110-5820 |
identifier_str_mv |
HAJJAR, Ludhmila Abrahão al. Intensive care management of patients with COVID-19: a practical approach. Annals of Intensive Care, Heidelberg, v. 11, p. 1-17, Feb. 2021. 2110-5820 10.1186/s13613-021-00820-w |
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https://www.arca.fiocruz.br/handle/icict/46374 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Jean-Louis Teboul, CHU Bicêtre, France |
publisher.none.fl_str_mv |
Jean-Louis Teboul, CHU Bicêtre, France |
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