Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole

Detalhes bibliográficos
Autor(a) principal: Daliry, Anissa
Data de Publicação: 2014
Outros Autores: Caldas, Ivo Santana, Diniz, Livia de Figueiredo, Torres, Rosália Morais, Talvani, André, Bahia, Maria Therezinha, Carvalho, Antônio Carlos Campos de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10612
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
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spelling Daliry, AnissaCaldas, Ivo SantanaDiniz, Livia de FigueiredoTorres, Rosália MoraisTalvani, AndréBahia, Maria TherezinhaCarvalho, Antônio Carlos Campos de2015-06-01T19:34:23Z2015-06-01T19:34:23Z2014DALIRY, Anissa et al. Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole. International Journal of Cardiology, v.170, n.3, p.e66–e67, 2014.0167-5273https://www.arca.fiocruz.br/handle/icict/1061210.1016/j.ijcard.2013.11.022engElsevierAnti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazoleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil.Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil.Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil.Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil.Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil.Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Chronic chagasic cardiomyopathy (CCC) is a public health problem still without a defined physiopathology. It results from a chronic infection by Trypanosoma cruzi and is characterized by irreversible lesions to the heart. The contribution of autoimmune processes to cardiac dysfunctions observed in CCC has been hypothesized by several authors [1–3]. Those studies demonstrated the presence of IgG components in sera of patients with CCC and dilated cardiomyopathy interacting with cardiac β1-adrenergic (anti-β1-AR) and muscarinic membrane receptors (anti-M2-CR) [3].Typanosoma cruziCadiomiopathyAutoantibodiesBeta-adrenergic receptorMuscarinic cholinergic receptorCardiomiopatia ChagásicaAutoanticorposTrypanosoma cruziinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10612/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALanissa_daliryetal_IOC_2014.pdfapplication/pdf126680https://www.arca.fiocruz.br/bitstream/icict/10612/2/anissa_daliryetal_IOC_2014.pdf82397f0381b66f510a15acec88f5c5a2MD52TEXTanissa_daliryetal_IOC_2014.pdf.txtanissa_daliryetal_IOC_2014.pdf.txtExtracted texttext/plain12623https://www.arca.fiocruz.br/bitstream/icict/10612/3/anissa_daliryetal_IOC_2014.pdf.txt3efdebcfc9ad1e377163c89c91486d0cMD53icict/106122022-06-24 13:02:55.094oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:02:55Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
title Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
spellingShingle Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
Daliry, Anissa
Typanosoma cruzi
Cadiomiopathy
Autoantibodies
Beta-adrenergic receptor
Muscarinic cholinergic receptor
Cardiomiopatia Chagásica
Autoanticorpos
Trypanosoma cruzi
title_short Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
title_full Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
title_fullStr Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
title_full_unstemmed Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
title_sort Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
author Daliry, Anissa
author_facet Daliry, Anissa
Caldas, Ivo Santana
Diniz, Livia de Figueiredo
Torres, Rosália Morais
Talvani, André
Bahia, Maria Therezinha
Carvalho, Antônio Carlos Campos de
author_role author
author2 Caldas, Ivo Santana
Diniz, Livia de Figueiredo
Torres, Rosália Morais
Talvani, André
Bahia, Maria Therezinha
Carvalho, Antônio Carlos Campos de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Daliry, Anissa
Caldas, Ivo Santana
Diniz, Livia de Figueiredo
Torres, Rosália Morais
Talvani, André
Bahia, Maria Therezinha
Carvalho, Antônio Carlos Campos de
dc.subject.en.pt_BR.fl_str_mv Typanosoma cruzi
Cadiomiopathy
Autoantibodies
Beta-adrenergic receptor
Muscarinic cholinergic receptor
topic Typanosoma cruzi
Cadiomiopathy
Autoantibodies
Beta-adrenergic receptor
Muscarinic cholinergic receptor
Cardiomiopatia Chagásica
Autoanticorpos
Trypanosoma cruzi
dc.subject.decs.pt_BR.fl_str_mv Cardiomiopatia Chagásica
Autoanticorpos
Trypanosoma cruzi
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-06-01T19:34:23Z
dc.date.available.fl_str_mv 2015-06-01T19:34:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DALIRY, Anissa et al. Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole. International Journal of Cardiology, v.170, n.3, p.e66–e67, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10612
dc.identifier.issn.pt_BR.fl_str_mv 0167-5273
dc.identifier.doi.pt_BR.fl_str_mv 10.1016/j.ijcard.2013.11.022
identifier_str_mv DALIRY, Anissa et al. Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole. International Journal of Cardiology, v.170, n.3, p.e66–e67, 2014.
0167-5273
10.1016/j.ijcard.2013.11.022
url https://www.arca.fiocruz.br/handle/icict/10612
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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