Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study

Detalhes bibliográficos
Autor(a) principal: Martins, Adenilda Lima Lopes
Data de Publicação: 2023
Outros Autores: Firmino, Alisson de Aquino, Boa-Sorte, Ney, Araújo, Jean Paulo Lacerda, Paixão, Taiane Silva, Viriato, Adriele Ribeiro França, Castro, Bernardo Galvão, Grassi, Maria Fernanda Rios
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1093/sexmed/qfad002
Texto Completo: https://www.arca.fiocruz.br/handle/icict/59010
Resumo: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Conselho Fundação Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Nacional para o Desenvolvimento do Ensino Superior (FUNDADESP). Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).
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spelling Martins, Adenilda Lima LopesFirmino, Alisson de AquinoBoa-Sorte, NeyAraújo, Jean Paulo LacerdaPaixão, Taiane SilvaViriato, Adriele Ribeiro FrançaCastro, Bernardo GalvãoGrassi, Maria Fernanda Rios2023-06-13T19:24:17Z2023-06-13T19:24:17Z2023MARTINS, Adenilda Lima Lopes et al. Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study. Sexual Medicine, v. 11, n. 2, p. 1-7, 2023. 2050-1161https://www.arca.fiocruz.br/handle/icict/5901010.1093/sexmed/qfad002Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Conselho Fundação Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Nacional para o Desenvolvimento do Ensino Superior (FUNDADESP). Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).Universidade Estadual de Feira de Santana. Feira de Santana, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Centro Integrativo e Interdisciplinar de HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil.Background: Human T-lymphotropic virus type-1 (HTLV-1) causes a variety of sicca symptoms, including xeroderma, xerostomia, and xerophthalmia. Aim: We sought to evaluate vaginal dryness via the degree of perceived vaginal lubrication, vaginal hormonal cytology, and direct measurements of vaginal wetting. Methods: The research was designed as a cross-sectional study. Vaginal dryness was assessed by scores in the lubrication domain of the Female Sexual Function Index (FSFI) questionnaire and the Vaginal Maturation Index (VMI) determined by vaginal hormonal cytology, as well as the measurement of vaginal lubrication using Schirmer strips placed at the anterior vaginal wall. Medians (25th-75th percentiles) were calculated for each group and compared using a nonparametric Kruskal-Wallis test and the Dunn-Bonferroni post hoc method. Outcomes: Outcomes were detection of the presence of vaginal dryness in women who were infected or noninfected with HTLV-1. Results: HTLV-1-infected women (n = 72, 57 asymptomatic and 15 with HTLV-1-associated myelopathy/tropical spastic paraparesis [HAM/TSP]) and uninfected women (n = 49) were studied. Women with HAM/TSP had significantly lower FSFI lubrication scores than asymptomatic and uninfected women (P = .032). In addition, women with HAM/TSP had significantly lower VMI compared with the asymptomatic and uninfected groups (P = .027 and P = .039, respectively). Clinical implications: The results of this study show a reduction in vaginal lubrication in HTLV-1-infected women diagnosed with HAM/TSP compared with asymptomatic and uninfected women. Strengths and limitations: The lack of a gold standard test for the diagnosis of vaginal dryness and the fact that no assessment of vaginal pH was performed were limitations of this study. The strength of the study was the comprehensive assessment of vaginal dryness from several perspectives: subjective (perception of vaginal lubrication according to the vaginal lubrication domain of the FSFI), hormonal (vaginal hormonal cytology to assess local hormone status), and the degree of vaginal moisture (direct measurement of vaginal dryness with an instrument, the Schirmer strip, already used to measure the presence of dry eye). Conclusion: HTLV-1-infected women with HAM/TSP have decreased vaginal lubrication compared with asymptomatic and uninfected women after adjusting for age.engElsevierÍndice de função sexual femininaHTLV-1Índice de maturação vaginalSecura vaginalFemale sexual function indexHTLV-1Vaginal maturation indexVaginal drynessSexo sem proteçãoFemininoInfecções por HTLV-IVaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/59010/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMartins, A. A. L. L. Vaginal dryness in women....pdfMartins, A. A. L. L. Vaginal dryness in women....pdfapplication/pdf308335https://www.arca.fiocruz.br/bitstream/icict/59010/2/Martins%2c%20A.%20A.%20L.%20L.%20Vaginal%20dryness%20in%20women....pdf313a8f2fc217c8e113c565e413f153daMD52icict/590102023-06-13 16:24:18.74oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-06-13T19:24:18Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
title Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
spellingShingle Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
Martins, Adenilda Lima Lopes
Índice de função sexual feminina
HTLV-1
Índice de maturação vaginal
Secura vaginal
Female sexual function index
HTLV-1
Vaginal maturation index
Vaginal dryness
Sexo sem proteção
Feminino
Infecções por HTLV-I
title_short Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
title_full Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
title_fullStr Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
title_full_unstemmed Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
title_sort Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study
author Martins, Adenilda Lima Lopes
author_facet Martins, Adenilda Lima Lopes
Firmino, Alisson de Aquino
Boa-Sorte, Ney
Araújo, Jean Paulo Lacerda
Paixão, Taiane Silva
Viriato, Adriele Ribeiro França
Castro, Bernardo Galvão
Grassi, Maria Fernanda Rios
author_role author
author2 Firmino, Alisson de Aquino
Boa-Sorte, Ney
Araújo, Jean Paulo Lacerda
Paixão, Taiane Silva
Viriato, Adriele Ribeiro França
Castro, Bernardo Galvão
Grassi, Maria Fernanda Rios
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins, Adenilda Lima Lopes
Firmino, Alisson de Aquino
Boa-Sorte, Ney
Araújo, Jean Paulo Lacerda
Paixão, Taiane Silva
Viriato, Adriele Ribeiro França
Castro, Bernardo Galvão
Grassi, Maria Fernanda Rios
dc.subject.other.en_US.fl_str_mv Índice de função sexual feminina
HTLV-1
Índice de maturação vaginal
Secura vaginal
topic Índice de função sexual feminina
HTLV-1
Índice de maturação vaginal
Secura vaginal
Female sexual function index
HTLV-1
Vaginal maturation index
Vaginal dryness
Sexo sem proteção
Feminino
Infecções por HTLV-I
dc.subject.en.en_US.fl_str_mv Female sexual function index
HTLV-1
Vaginal maturation index
Vaginal dryness
dc.subject.decs.en_US.fl_str_mv Sexo sem proteção
Feminino
Infecções por HTLV-I
description Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Conselho Fundação Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Nacional para o Desenvolvimento do Ensino Superior (FUNDADESP). Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-06-13T19:24:17Z
dc.date.available.fl_str_mv 2023-06-13T19:24:17Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARTINS, Adenilda Lima Lopes et al. Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study. Sexual Medicine, v. 11, n. 2, p. 1-7, 2023. 
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/59010
dc.identifier.issn.en_US.fl_str_mv 2050-1161
dc.identifier.doi.none.fl_str_mv 10.1093/sexmed/qfad002
identifier_str_mv MARTINS, Adenilda Lima Lopes et al. Vaginal dryness in women infected by human T-lymphotropic virus type 1: an exploratory study. Sexual Medicine, v. 11, n. 2, p. 1-7, 2023. 
2050-1161
10.1093/sexmed/qfad002
url https://www.arca.fiocruz.br/handle/icict/59010
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/59010/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/59010/2/Martins%2c%20A.%20A.%20L.%20L.%20Vaginal%20dryness%20in%20women....pdf
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