Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome

Detalhes bibliográficos
Autor(a) principal: Melo, Caroline Vilas Boas de
Data de Publicação: 2020
Outros Autores: Tavares, Maria Brandão, Fernandes, Paula Neves, Silva, Carlos Alberto dos Santos, Couto, Ricardo David, Oliveira, Marília Bahiense, dosSantos, Washington Luis Conrado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44349
Resumo: Research Ethical Committee of Fundação Oswaldo Cruz, Instituto Gonçalo Moniz, Salvador, BA, Brazil, Protocol No. 184.419.
id CRUZ_1a05874691b00f5235f85aca657f110d
oai_identifier_str oai:www.arca.fiocruz.br:icict/44349
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Melo, Caroline Vilas Boas deTavares, Maria BrandãoFernandes, Paula NevesSilva, Carlos Alberto dos SantosCouto, Ricardo DavidOliveira, Marília BahiensedosSantos, Washington Luis Conrado2020-11-09T14:38:19Z2020-11-09T14:38:19Z2020MELO, Caroline Vilas Boas de et al. Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome. BMC Research Notes, v. 13, 2020.1756-0500https://www.arca.fiocruz.br/handle/icict/4434910.1186/s13104-020-05244-6Research Ethical Committee of Fundação Oswaldo Cruz, Instituto Gonçalo Moniz, Salvador, BA, Brazil, Protocol No. 184.419.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Pública. Salvador, Ba, Brasil.Federal University of Bahia. Medicine Department. Salvador, BA, Brazil.Federal University of Bahia. Pharmaceutic Department. Salvador, BA, Brazil.Ana Nery Hospital. Nephrology Department. Salvador, BA, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Objective: Acute tubular necrosis (ATN) is a frequent cause of acute kidney injury (AKI). In patients with nephrotic syndrome (NS), AKI demands the differential diagnosis between ATN and rapidly progressive glomerulonephritis. In some cases, conclusive diagnosis is possible only by kidney biopsy. We aimed to study the potential use of urine cytology in the differential diagnosis between ATN and proliferative glomerular lesion in patients with NS. Results: Cell size analysis showed a higher proportion of small cells and a lower proportion of large cells in the urine of patients with AKI. Cells phenotypes were easily defined using cytological preparations. Leukocytes were found to be a primary classifier of NS groups, with higher number in patients with AKI and patients with proliferative glomerular lesions. Although renal biopsy is still required for confirmative diagnosis, our data suggests that urinary cytology can be readily performed andengBMCNecrose tubular agudaGlomerulonefriteCitodiagnósticoLesão renal agudaAcute tubular necrosisGlomerulonephritisCytodiagnosisAcute kidney injuryUrinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndromeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/44349/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALMello, Caroline Vilas Boas. Urinary....pdfMello, Caroline Vilas Boas. Urinary....pdfapplication/pdf997802https://www.arca.fiocruz.br/bitstream/icict/44349/2/Mello%2c%20Caroline%20Vilas%20Boas.%20Urinary....pdfac2d0ee26953ae0e9a56917c582b57e3MD52TEXTMello, Caroline Vilas Boas. Urinary....pdf.txtMello, Caroline Vilas Boas. Urinary....pdf.txtExtracted texttext/plain26454https://www.arca.fiocruz.br/bitstream/icict/44349/3/Mello%2c%20Caroline%20Vilas%20Boas.%20Urinary....pdf.txt3819409f8729594ac69dcbc98e392a98MD53icict/443492023-03-15 14:34:26.053oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:26Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
title Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
spellingShingle Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
Melo, Caroline Vilas Boas de
Necrose tubular aguda
Glomerulonefrite
Citodiagnóstico
Lesão renal aguda
Acute tubular necrosis
Glomerulonephritis
Cytodiagnosis
Acute kidney injury
title_short Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
title_full Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
title_fullStr Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
title_full_unstemmed Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
title_sort Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome
author Melo, Caroline Vilas Boas de
author_facet Melo, Caroline Vilas Boas de
Tavares, Maria Brandão
Fernandes, Paula Neves
Silva, Carlos Alberto dos Santos
Couto, Ricardo David
Oliveira, Marília Bahiense
dosSantos, Washington Luis Conrado
author_role author
author2 Tavares, Maria Brandão
Fernandes, Paula Neves
Silva, Carlos Alberto dos Santos
Couto, Ricardo David
Oliveira, Marília Bahiense
dosSantos, Washington Luis Conrado
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo, Caroline Vilas Boas de
Tavares, Maria Brandão
Fernandes, Paula Neves
Silva, Carlos Alberto dos Santos
Couto, Ricardo David
Oliveira, Marília Bahiense
dosSantos, Washington Luis Conrado
dc.subject.other.pt_BR.fl_str_mv Necrose tubular aguda
Glomerulonefrite
Citodiagnóstico
Lesão renal aguda
topic Necrose tubular aguda
Glomerulonefrite
Citodiagnóstico
Lesão renal aguda
Acute tubular necrosis
Glomerulonephritis
Cytodiagnosis
Acute kidney injury
dc.subject.en.pt_BR.fl_str_mv Acute tubular necrosis
Glomerulonephritis
Cytodiagnosis
Acute kidney injury
description Research Ethical Committee of Fundação Oswaldo Cruz, Instituto Gonçalo Moniz, Salvador, BA, Brazil, Protocol No. 184.419.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-11-09T14:38:19Z
dc.date.available.fl_str_mv 2020-11-09T14:38:19Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MELO, Caroline Vilas Boas de et al. Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome. BMC Research Notes, v. 13, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44349
dc.identifier.issn.pt_BR.fl_str_mv 1756-0500
dc.identifier.doi.none.fl_str_mv 10.1186/s13104-020-05244-6
identifier_str_mv MELO, Caroline Vilas Boas de et al. Urinary cytology: a potential tool for differential diagnosis of acute kidney injury in patients with nephrotic syndrome. BMC Research Notes, v. 13, 2020.
1756-0500
10.1186/s13104-020-05244-6
url https://www.arca.fiocruz.br/handle/icict/44349
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/44349/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/44349/2/Mello%2c%20Caroline%20Vilas%20Boas.%20Urinary....pdf
https://www.arca.fiocruz.br/bitstream/icict/44349/3/Mello%2c%20Caroline%20Vilas%20Boas.%20Urinary....pdf.txt
bitstream.checksum.fl_str_mv 36b51ef91c52b5338d9d29ba0cc807bc
ac2d0ee26953ae0e9a56917c582b57e3
3819409f8729594ac69dcbc98e392a98
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008861763731456

Registros relacionados