Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/10414 |
Resumo: | Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil. |
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Louredo, Liliane SimpsonRamos, Juliana NunesPeixoto, Renta StavracakisSantos, Louisy SanchesAntunes, Camila AzevedoLadeira, Elisa MartinsSantos, Cintia SilvaVieira, Veronica VianaVillas Bôas, Maria Helena SimõesHirata Jr., RaphaelGuaraldi, Ana Luiza Mattos2015-05-19T13:26:09Z2015-05-19T13:26:09Z2014LOUREDO, Liliane Simpson et al. Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles. Antonie van Leeuwenhoek, v.105, n.2, p 343-352, 2014.1572-9699https://www.arca.fiocruz.br/handle/icict/1041410.1007/s10482-013-0080-5engSpringerCorynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profilesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Professor Paulo de Góes. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade na Saúde (INCQS). Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil.Corynebacterium ulcerans has been increasingly isolated as an emerging zoonotic agent of diphtheria and other infections from companion animals. Since pets are able to act as symptomless carriers, it is also essential to identify virulence potential for humans of these isolates. In this work the ability of C. ulcerans to bind to fibrinogen (Fbg), fibronectin (Fn) and Type I collagen as well the genetic relationship among strains isolated from human and asymptomatic dogs in Rio de Janeiro (Brazil) were analyzed. Five pulsed-field gel electrophoresis (PFGE) profiles were demonstrated (I, II, III, IV and V). In addition, the IV and V profiles exhibiting ≥85 % similarity were expressed by the BR-AD41 and BR-AD61 strains from companion dogs living in the same neighborhood. Independent of the PFGE-types, human and dog isolates showed affinity to Fbg, Fn and collagen. Heterogeneity of PFGE profiles indicated endemicity of C. ulcerans in the Rio de Janeiro metropolitan area. Differences in the expression of adhesins to the human extracellular matrix may contribute to variations in the virulence and zoonotic potential of C. ulcerans strains.Corynebacterium ulceransFibrinogenFibrincetinFibronectinPFGEFibrinógenoFibronectinasFibrinogênioFibronectinasinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10414/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALliliane_louredoetal_IOC_2014.pdfapplication/pdf319797https://www.arca.fiocruz.br/bitstream/icict/10414/2/liliane_louredoetal_IOC_2014.pdf2b4ef156764700cf7ed1f20bca4ec950MD52TEXTliliane_louredoetal_IOC_2014.pdf.txtliliane_louredoetal_IOC_2014.pdf.txtExtracted texttext/plain38167https://www.arca.fiocruz.br/bitstream/icict/10414/3/liliane_louredoetal_IOC_2014.pdf.txt506c4818798d794570733016bc1992c8MD53icict/104142022-06-24 12:19:37.542oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:19:37Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| title |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| spellingShingle |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles Louredo, Liliane Simpson Corynebacterium ulcerans Fibrinogen Fibrincetin Fibronectin PFGE Fibrinógeno Fibronectinas Fibrinogênio Fibronectinas |
| title_short |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| title_full |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| title_fullStr |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| title_full_unstemmed |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| title_sort |
Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles |
| author |
Louredo, Liliane Simpson |
| author_facet |
Louredo, Liliane Simpson Ramos, Juliana Nunes Peixoto, Renta Stavracakis Santos, Louisy Sanches Antunes, Camila Azevedo Ladeira, Elisa Martins Santos, Cintia Silva Vieira, Veronica Viana Villas Bôas, Maria Helena Simões Hirata Jr., Raphael Guaraldi, Ana Luiza Mattos |
| author_role |
author |
| author2 |
Ramos, Juliana Nunes Peixoto, Renta Stavracakis Santos, Louisy Sanches Antunes, Camila Azevedo Ladeira, Elisa Martins Santos, Cintia Silva Vieira, Veronica Viana Villas Bôas, Maria Helena Simões Hirata Jr., Raphael Guaraldi, Ana Luiza Mattos |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Louredo, Liliane Simpson Ramos, Juliana Nunes Peixoto, Renta Stavracakis Santos, Louisy Sanches Antunes, Camila Azevedo Ladeira, Elisa Martins Santos, Cintia Silva Vieira, Veronica Viana Villas Bôas, Maria Helena Simões Hirata Jr., Raphael Guaraldi, Ana Luiza Mattos |
| dc.subject.en.pt_BR.fl_str_mv |
Corynebacterium ulcerans Fibrinogen Fibrincetin Fibronectin PFGE |
| topic |
Corynebacterium ulcerans Fibrinogen Fibrincetin Fibronectin PFGE Fibrinógeno Fibronectinas Fibrinogênio Fibronectinas |
| dc.subject.es.pt_BR.fl_str_mv |
Fibrinógeno Fibronectinas |
| dc.subject.decs.pt_BR.fl_str_mv |
Fibrinogênio Fibronectinas |
| description |
Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Difteria e Corynebacteria de Relevância Clínica. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde (INCQS). Rio de Janeiro, RJ, Brasil. |
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2014 |
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2014 |
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2015-05-19T13:26:09Z |
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2015-05-19T13:26:09Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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LOUREDO, Liliane Simpson et al. Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles. Antonie van Leeuwenhoek, v.105, n.2, p 343-352, 2014. |
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https://www.arca.fiocruz.br/handle/icict/10414 |
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1572-9699 |
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10.1007/s10482-013-0080-5 |
| identifier_str_mv |
LOUREDO, Liliane Simpson et al. Corynebacterium ulcerans isolates from humans and dogs: fibrinogen, fibronectin and collagen-binding, antimicrobial and PFGE profiles. Antonie van Leeuwenhoek, v.105, n.2, p 343-352, 2014. 1572-9699 10.1007/s10482-013-0080-5 |
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eng |
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Springer |
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Springer |
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