From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide

Detalhes bibliográficos
Autor(a) principal: Schechtman, Helio
Data de Publicação: 2020
Outros Autores: Valle, Denise, Souza, Max O.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47744
Resumo: Fundação Oswaldo Cruz. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.
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spelling Schechtman, HelioValle, DeniseSouza, Max O.2021-06-17T14:19:38Z2021-06-17T14:19:38Z2020SCHECHTMAN, Helio; VALLE, Denise; SOUZA, Max. O. From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. Plos Negl Trop Dis., v. 14, n. 11, e0008862, 17 p, Nov. 2020.1935-2727https://www.arca.fiocruz.br/handle/icict/4774410.1371/journal.pntd.00088621935-2735engPublic Library of ScienceModelo matemáticoUso indiscriminadoInseticidasMathematical modelIndiscriminate useInsecticideFrom resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticideinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Flavivírus. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM)/CNPq. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Matemática e Estatística. Niterói, RJ, Brasil.The development of insecticide resistance is becoming a threat to many arboviruses control programs worldwide. While this has been attributed to the indiscriminate use of insecticide, a more theoretical study is apparently not available. Using in-silico experiments, we investi gated the effects of two different policies: one used by the Brazilian Ministry of Health (which follows the World Health Organization protocol) and a more permissive one, akin to those employed by various gated communities and private companies. The results show that the public policy does not lead to resistance fixation. On the other hand, permissive application of adulticide, such as intensive domestic use mainly during epidemic periods, might lead to the fixation of a resistant population, even when resistance is associated with moderate fit ness costs.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/47744/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALDenise_Valle_IOC_2020.pdfDenise_Valle_IOC_2020.pdfapplication/pdf2326516https://www.arca.fiocruz.br/bitstream/icict/47744/2/Denise_Valle_IOC_2020.pdf4379a72d5e687e5fae9cf7a7f2f22db0MD52TEXTDenise_Valle_IOC_2020.pdf.txtDenise_Valle_IOC_2020.pdf.txtExtracted texttext/plain54163https://www.arca.fiocruz.br/bitstream/icict/47744/3/Denise_Valle_IOC_2020.pdf.txt356947377623cc00f0c0ed667d0a4dcbMD53icict/477442021-06-18 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dc.title.pt_BR.fl_str_mv From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
title From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
spellingShingle From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
Schechtman, Helio
Modelo matemático
Uso indiscriminado
Inseticidas
Mathematical model
Indiscriminate use
Insecticide
title_short From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
title_full From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
title_fullStr From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
title_full_unstemmed From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
title_sort From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide
author Schechtman, Helio
author_facet Schechtman, Helio
Valle, Denise
Souza, Max O.
author_role author
author2 Valle, Denise
Souza, Max O.
author2_role author
author
dc.contributor.author.fl_str_mv Schechtman, Helio
Valle, Denise
Souza, Max O.
dc.subject.other.pt_BR.fl_str_mv Modelo matemático
Uso indiscriminado
Inseticidas
topic Modelo matemático
Uso indiscriminado
Inseticidas
Mathematical model
Indiscriminate use
Insecticide
dc.subject.en.pt_BR.fl_str_mv Mathematical model
Indiscriminate use
Insecticide
description Fundação Oswaldo Cruz. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-06-17T14:19:38Z
dc.date.available.fl_str_mv 2021-06-17T14:19:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SCHECHTMAN, Helio; VALLE, Denise; SOUZA, Max. O. From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. Plos Negl Trop Dis., v. 14, n. 11, e0008862, 17 p, Nov. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47744
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0008862
dc.identifier.eissn.none.fl_str_mv 1935-2735
identifier_str_mv SCHECHTMAN, Helio; VALLE, Denise; SOUZA, Max. O. From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. Plos Negl Trop Dis., v. 14, n. 11, e0008862, 17 p, Nov. 2020.
1935-2727
10.1371/journal.pntd.0008862
1935-2735
url https://www.arca.fiocruz.br/handle/icict/47744
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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