A tale from TGF-β superfamily for thymus ontogeny and function
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/12771 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento. Rio de Janeiro, RJ, Brasil. |
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Jurberg, Arnon DiasFontes, Larissa VasconcelosAlmeida, Vinicius Cotta de2016-02-22T11:51:10Z2016-02-22T11:51:10Z2015JURBERG, Arnon Dias; FONTES, Larissa Vasconcelos; ALMEIDA, Vinícius Cotta de. A tale from TGF-β superfamily for thymus ontogeny and function. Frontiers in Immunology, v.6, Article 442, 15p, Aug. 2015.1664-3224https://www.arca.fiocruz.br/handle/icict/1277110.3389/fimmu.2015.00442engFrontiers MediaA tale from TGF-β superfamily for thymus ontogeny and functioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil.Multiple signaling pathways control every aspect of cell behavior, organ formation, and tissue homeostasis throughout the lifespan of any individual. This review takes an ontogenetic view focused on the large superfamily of TGF-β/bone morphogenetic protein ligands to address thymus morphogenesis and function in T cell differentiation. Recent findings on a role of GDF11 for reversing aging-related phenotypes are also discussed.TGF-βBMPThymusThymopoiesisT cell developmentTimoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/12771/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALarnon_jurberg_etal_IOC_2015.pdfarnon_jurberg_etal_IOC_2015.pdfapplication/pdf1782164https://www.arca.fiocruz.br/bitstream/icict/12771/2/arnon_jurberg_etal_IOC_2015.pdf42f8074c55b1ad2da3656a7927ec7c1dMD52TEXTarnon_jurberg_etal_IOC_2015.pdf.txtarnon_jurberg_etal_IOC_2015.pdf.txtExtracted texttext/plain104530https://www.arca.fiocruz.br/bitstream/icict/12771/3/arnon_jurberg_etal_IOC_2015.pdf.txtdd4d14331d3649a0632ff62384a2f8ddMD53icict/127712023-09-05 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dc.title.pt_BR.fl_str_mv |
A tale from TGF-β superfamily for thymus ontogeny and function |
title |
A tale from TGF-β superfamily for thymus ontogeny and function |
spellingShingle |
A tale from TGF-β superfamily for thymus ontogeny and function Jurberg, Arnon Dias TGF-β BMP Thymus Thymopoiesis T cell development Timo |
title_short |
A tale from TGF-β superfamily for thymus ontogeny and function |
title_full |
A tale from TGF-β superfamily for thymus ontogeny and function |
title_fullStr |
A tale from TGF-β superfamily for thymus ontogeny and function |
title_full_unstemmed |
A tale from TGF-β superfamily for thymus ontogeny and function |
title_sort |
A tale from TGF-β superfamily for thymus ontogeny and function |
author |
Jurberg, Arnon Dias |
author_facet |
Jurberg, Arnon Dias Fontes, Larissa Vasconcelos Almeida, Vinicius Cotta de |
author_role |
author |
author2 |
Fontes, Larissa Vasconcelos Almeida, Vinicius Cotta de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Jurberg, Arnon Dias Fontes, Larissa Vasconcelos Almeida, Vinicius Cotta de |
dc.subject.en.pt_BR.fl_str_mv |
TGF-β BMP Thymus Thymopoiesis T cell development |
topic |
TGF-β BMP Thymus Thymopoiesis T cell development Timo |
dc.subject.decs.pt_BR.fl_str_mv |
Timo |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento. Rio de Janeiro, RJ, Brasil. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
dc.date.accessioned.fl_str_mv |
2016-02-22T11:51:10Z |
dc.date.available.fl_str_mv |
2016-02-22T11:51:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
JURBERG, Arnon Dias; FONTES, Larissa Vasconcelos; ALMEIDA, Vinícius Cotta de. A tale from TGF-β superfamily for thymus ontogeny and function. Frontiers in Immunology, v.6, Article 442, 15p, Aug. 2015. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/12771 |
dc.identifier.issn.none.fl_str_mv |
1664-3224 |
dc.identifier.doi.none.fl_str_mv |
10.3389/fimmu.2015.00442 |
identifier_str_mv |
JURBERG, Arnon Dias; FONTES, Larissa Vasconcelos; ALMEIDA, Vinícius Cotta de. A tale from TGF-β superfamily for thymus ontogeny and function. Frontiers in Immunology, v.6, Article 442, 15p, Aug. 2015. 1664-3224 10.3389/fimmu.2015.00442 |
url |
https://www.arca.fiocruz.br/handle/icict/12771 |
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eng |
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eng |
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Frontiers Media |
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Frontiers Media |
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