Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1007/s42770-021-00550-y |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/53415 |
Resumo: | Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil. |
| id |
CRUZ_2d93d0e78f1df475c1bca56833a4d2bf |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/53415 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Fraiha, Ana Luiza SoaresMatos, Ana Carolina DinizCunha, João Luis ReisSantos, Beatriz Senra Álvares da SilvaPeixoto, Maria Vitória ChavesOliveira, Anna Gabriella GuimarãesGalinari, Grazielle Cossenzo FlorentinoNascimento, Heloíza Irtes de JesusGuedes, Maria Isabel Maldonado CoelhoMachado, Alexandre de Magalhães VieiraCosta, Erica AzevedoLobato, Zélia Inês Portela2022-06-22T12:52:46Z2022-06-22T12:52:46Z2021FRAIHA, Ana Luiza Soares et al. Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. Braz J Microbiol., v. 52, n. 4, p. 2421-2430, 2021. doi: 10.1007/s42770-021-00550-y.1678-4405https://www.arca.fiocruz.br/handle/icict/5341510.1007/s42770-021-00550-yengSpringer International PublishingSwine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil/Fundação Oswaldo Cruz. Instituto de Pesquisa René Rachou. Laboratório de Imunologia de Doenças Virais. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa René Rachou. Laboratório de Imunologia de Doenças Virais. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil.The swine influenza A virus (SIAV) subtypes/lineages H1N1pdm09, H3N2, H1N2, and H1N1 of seasonal human origin are widespread in Brazilian swine herds. A monovalent inactivated H1N1pdm09 vaccine was licensed in Brazil in 2014. However, there are concerns about its efficacy due to the limited vaccine cross-protection against heterologous viruses and the potential for exacerbated reactions against vaccine strains. Thus, monitoring SIAVs subtypes/lineages that are circulating in the Brazilian swine population is important, by applying a fast and efficient diagnostic test in herd field samples. A RT-PCR assay was developed, using primers specific for HA subtyping of Brazilian SIAV, and was used to evaluate the occurrence of subtypes from samples collected between 2012 and 2019. From 167 field samples positive for influenza A, 117 were subtyped by nested RT-PCR assay. A higher occurrence of H1N1pdm was observed from 2012 to 2015, H3N2 in 2017, and H1hu in 2017 to 2019. A hemagglutination inhibition test was performed in serum samples received from 2017 to 2019, confirming these data. The molecular data highlights the importance of H1hu and H3N2 detection since there are no vaccines available for the subtypes/lineages and raises an alert of H1hu for its potential to infect humans. Serological data suggest a cyclical profile of occurrence between the H3N2 and H1N1pdm over time. Monitoring SIAVs circulating in Brazilian swine herds is necessary, which provides the relevant information for field veterinarians to apply effective control measures on the properties.BrazilGenotypingH1N1pdmH1huH3N2Influenza virusSerologySwineinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/53415/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALSwine influenza A virus subtypes circulating.pdfSwine influenza A virus subtypes circulating.pdfapplication/pdf507036https://www.arca.fiocruz.br/bitstream/icict/53415/2/Swine%20influenza%20A%20virus%20subtypes%20circulating.pdf488ef68f437722cf9c1c9b176211dfcdMD52icict/534152022-06-22 09:52:46.778oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-22T12:52:46Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| title |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| spellingShingle |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. Fraiha, Ana Luiza Soares Brazil Genotyping H1N1pdm H1hu H3N2 Influenza virus Serology Swine |
| title_short |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| title_full |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| title_fullStr |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| title_full_unstemmed |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| title_sort |
Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. |
| author |
Fraiha, Ana Luiza Soares |
| author_facet |
Fraiha, Ana Luiza Soares Matos, Ana Carolina Diniz Cunha, João Luis Reis Santos, Beatriz Senra Álvares da Silva Peixoto, Maria Vitória Chaves Oliveira, Anna Gabriella Guimarães Galinari, Grazielle Cossenzo Florentino Nascimento, Heloíza Irtes de Jesus Guedes, Maria Isabel Maldonado Coelho Machado, Alexandre de Magalhães Vieira Costa, Erica Azevedo Lobato, Zélia Inês Portela |
| author_role |
author |
| author2 |
Matos, Ana Carolina Diniz Cunha, João Luis Reis Santos, Beatriz Senra Álvares da Silva Peixoto, Maria Vitória Chaves Oliveira, Anna Gabriella Guimarães Galinari, Grazielle Cossenzo Florentino Nascimento, Heloíza Irtes de Jesus Guedes, Maria Isabel Maldonado Coelho Machado, Alexandre de Magalhães Vieira Costa, Erica Azevedo Lobato, Zélia Inês Portela |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Fraiha, Ana Luiza Soares Matos, Ana Carolina Diniz Cunha, João Luis Reis Santos, Beatriz Senra Álvares da Silva Peixoto, Maria Vitória Chaves Oliveira, Anna Gabriella Guimarães Galinari, Grazielle Cossenzo Florentino Nascimento, Heloíza Irtes de Jesus Guedes, Maria Isabel Maldonado Coelho Machado, Alexandre de Magalhães Vieira Costa, Erica Azevedo Lobato, Zélia Inês Portela |
| dc.subject.en.pt_BR.fl_str_mv |
Brazil Genotyping H1N1pdm H1hu H3N2 Influenza virus Serology Swine |
| topic |
Brazil Genotyping H1N1pdm H1hu H3N2 Influenza virus Serology Swine |
| description |
Universidade Federal de Minas Gerais. Escola de Veterinária. Departamento de Medicina Veterinária Preventiva. Laboratório de Pesquisa em Virologia Animal. Belo Horizonte, MG, Brazil. |
| publishDate |
2021 |
| dc.date.issued.fl_str_mv |
2021 |
| dc.date.accessioned.fl_str_mv |
2022-06-22T12:52:46Z |
| dc.date.available.fl_str_mv |
2022-06-22T12:52:46Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
FRAIHA, Ana Luiza Soares et al. Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. Braz J Microbiol., v. 52, n. 4, p. 2421-2430, 2021. doi: 10.1007/s42770-021-00550-y. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/53415 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1678-4405 |
| dc.identifier.doi.none.fl_str_mv |
10.1007/s42770-021-00550-y |
| identifier_str_mv |
FRAIHA, Ana Luiza Soares et al. Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. Braz J Microbiol., v. 52, n. 4, p. 2421-2430, 2021. doi: 10.1007/s42770-021-00550-y. 1678-4405 10.1007/s42770-021-00550-y |
| url |
https://www.arca.fiocruz.br/handle/icict/53415 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Springer International Publishing |
| publisher.none.fl_str_mv |
Springer International Publishing |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/53415/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/53415/2/Swine%20influenza%20A%20virus%20subtypes%20circulating.pdf |
| bitstream.checksum.fl_str_mv |
9193a7c197bc67acd023525e72a03240 488ef68f437722cf9c1c9b176211dfcd |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1822792025501597696 |