Maternal-fetal transmission of the zika virus: An intriguing interplay

Detalhes bibliográficos
Autor(a) principal: Zanluca, Camila
Data de Publicação: 2018
Outros Autores: Noronha, Lucia de, Santos, Claudia Nunes Duarte dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25295
Resumo: 2018-11-07
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spelling Zanluca, CamilaNoronha, Lucia deSantos, Claudia Nunes Duarte dos2018-03-13T18:00:03Z2018-03-13T18:00:03Z2018ZANLUCA, Camila; NORONHA, Lucia de; SANTOS, Claudia Nunes dos. Maternal-fetal transmission of the zika virus: an intriguing interplay. Tissue Barriers, v.6, n.1, p. 1-31, 2018.https://www.arca.fiocruz.br/handle/icict/2529510.1080/21688370.2017.1402143engTaylor & FrancisMaternal-fetal transmission of the zika virus: An intriguing interplayinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2018-11-07Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil.Pontifícia Universidade Católica do Paraná. Laboratório de Patologia Experimental, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil.In this review, we give an overview of aspects related to the congenital transmission of the Zika virus (ZIKV). Although we acknowledge that important advances in research on ZIKV pathogenesis have come from studies using animal models, particularly non-human primates, this review emphasizes studies using ex-vivo human cells and tissues as well as natural infections in pregnant women. The possible routes used by ZIKV to cross or breach the placental barrier and infect the fetal central nervous system are presented. Understanding the viral infection biology and ZIKV pathogenesis during pregnancy may guide the design of affordable antiviral strategies to benefit pregnant women in areas at risk.Hofbauer cellsZika VirusPlacental BarriersMaternal-Fetal TransmissionNatural InfectionsEx Vivo ModelsSimPublicadoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/25295/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALMater_fetal_Zik.pdfMater_fetal_Zik.pdfapplication/pdf1698662https://www.arca.fiocruz.br/bitstream/icict/25295/2/Mater_fetal_Zik.pdffd08de7bbcd5b7edca329860e0c2999cMD52TEXTMater_fetal_Zik.pdf.txtMater_fetal_Zik.pdf.txtExtracted texttext/plain50030https://www.arca.fiocruz.br/bitstream/icict/25295/3/Mater_fetal_Zik.pdf.txt11302ce277f446d39a25e22c6bc5593fMD53icict/252952021-03-24 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dc.title.pt_BR.fl_str_mv Maternal-fetal transmission of the zika virus: An intriguing interplay
title Maternal-fetal transmission of the zika virus: An intriguing interplay
spellingShingle Maternal-fetal transmission of the zika virus: An intriguing interplay
Zanluca, Camila
Hofbauer cells
Zika Virus
Placental Barriers
Maternal-Fetal Transmission
Natural Infections
Ex Vivo Models
title_short Maternal-fetal transmission of the zika virus: An intriguing interplay
title_full Maternal-fetal transmission of the zika virus: An intriguing interplay
title_fullStr Maternal-fetal transmission of the zika virus: An intriguing interplay
title_full_unstemmed Maternal-fetal transmission of the zika virus: An intriguing interplay
title_sort Maternal-fetal transmission of the zika virus: An intriguing interplay
author Zanluca, Camila
author_facet Zanluca, Camila
Noronha, Lucia de
Santos, Claudia Nunes Duarte dos
author_role author
author2 Noronha, Lucia de
Santos, Claudia Nunes Duarte dos
author2_role author
author
dc.contributor.author.fl_str_mv Zanluca, Camila
Noronha, Lucia de
Santos, Claudia Nunes Duarte dos
dc.subject.en.pt_BR.fl_str_mv Hofbauer cells
Zika Virus
Placental Barriers
Maternal-Fetal Transmission
Natural Infections
Ex Vivo Models
topic Hofbauer cells
Zika Virus
Placental Barriers
Maternal-Fetal Transmission
Natural Infections
Ex Vivo Models
description 2018-11-07
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-03-13T18:00:03Z
dc.date.available.fl_str_mv 2018-03-13T18:00:03Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ZANLUCA, Camila; NORONHA, Lucia de; SANTOS, Claudia Nunes dos. Maternal-fetal transmission of the zika virus: an intriguing interplay. Tissue Barriers, v.6, n.1, p. 1-31, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25295
10.1080/21688370.2017.1402143
identifier_str_mv ZANLUCA, Camila; NORONHA, Lucia de; SANTOS, Claudia Nunes dos. Maternal-fetal transmission of the zika virus: an intriguing interplay. Tissue Barriers, v.6, n.1, p. 1-31, 2018.
10.1080/21688370.2017.1402143
url https://www.arca.fiocruz.br/handle/icict/25295
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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