Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/552 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. |
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Bongertz, VeraReis, Elaine Priscilla OuverneyTeixeira, Sylvia Lopes MaiaJesus, Carlos Silva deVilas-Boas Hacker, Mariana de AndreaMorgado, Mariza GonçalvesBastos, Francisco Inácio Pinkusfeld Monteiro2010-08-23T16:58:24Z2010-11-04T14:19:46Z2010-08-23T16:58:24Z2010-11-04T14:19:46Z2003BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003.0074-0276https://www.arca.fiocruz.br/handle/icict/55210.1590/S0074-02762003000200007engFundação Oswaldo Cruzhuman immunodeficiency virus-1Antibodiesinjection drug usersAnti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individualsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Rio de Janeiro, RJ, Brasil.Sera from infected injection drug users (IDU) have shown to have antibodies against synthetic human immunodeficiency virus-1 (HIV-1) envelope peptides more frequently. In this study, reactivity of 48 IDU plasma were compared to 60 plasmas obtained from sexually infected individuals (S). The overall reactivity of plasma from IDU compared to S was higher, and the reactivity titers were much higher for IDU plasma than S. IDU plasma also showed a broader antibody response. The higher reactivity titers were observed mainly for the gp41 immunodominant epitope and V3 peptides corresponding to the consensus sequences of HIV-1 subtypes/variants prevalent in Brazil (B, F, C) indicating the specificity in the higher immune response of IDU.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZTEXTBastos_Anti-human immunodeficienty_2003.pdf.txtBastos_Anti-human immunodeficienty_2003.pdf.txtExtracted texttext/plain20024https://www.arca.fiocruz.br/bitstream/icict/552/6/Bastos_Anti-human%20immunodeficienty_2003.pdf.txtec430460fb4ef245f627bb46b515233dMD56ORIGINALBastos_Anti-human immunodeficienty_2003.pdfapplication/pdf50084https://www.arca.fiocruz.br/bitstream/icict/552/2/Bastos_Anti-human%20immunodeficienty_2003.pdf0c16dfd094c5128949ca49b80520cb9eMD52LICENSElicense.txttext/plain1841https://www.arca.fiocruz.br/bitstream/icict/552/3/license.txt1c7bab69f8f9749b10817a04ad964e54MD53THUMBNAILBastos_Anti-human immunodeficienty_2003.pdf.jpgBastos_Anti-human immunodeficienty_2003.pdf.jpgGenerated Thumbnailimage/jpeg2370https://www.arca.fiocruz.br/bitstream/icict/552/5/Bastos_Anti-human%20immunodeficienty_2003.pdf.jpg428e484b2f9a85a4a8c735189752e4d9MD55icict/5522023-09-04 11:10:59.672oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T14:10:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
title |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
spellingShingle |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals Bongertz, Vera human immunodeficiency virus-1 Antibodies injection drug users |
title_short |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
title_full |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
title_fullStr |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
title_full_unstemmed |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
title_sort |
Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals |
author |
Bongertz, Vera |
author_facet |
Bongertz, Vera Reis, Elaine Priscilla Ouverney Teixeira, Sylvia Lopes Maia Jesus, Carlos Silva de Vilas-Boas Hacker, Mariana de Andrea Morgado, Mariza Gonçalves Bastos, Francisco Inácio Pinkusfeld Monteiro |
author_role |
author |
author2 |
Reis, Elaine Priscilla Ouverney Teixeira, Sylvia Lopes Maia Jesus, Carlos Silva de Vilas-Boas Hacker, Mariana de Andrea Morgado, Mariza Gonçalves Bastos, Francisco Inácio Pinkusfeld Monteiro |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bongertz, Vera Reis, Elaine Priscilla Ouverney Teixeira, Sylvia Lopes Maia Jesus, Carlos Silva de Vilas-Boas Hacker, Mariana de Andrea Morgado, Mariza Gonçalves Bastos, Francisco Inácio Pinkusfeld Monteiro |
dc.subject.por.fl_str_mv |
human immunodeficiency virus-1 Antibodies injection drug users |
topic |
human immunodeficiency virus-1 Antibodies injection drug users |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003 |
dc.date.accessioned.fl_str_mv |
2010-08-23T16:58:24Z 2010-11-04T14:19:46Z |
dc.date.available.fl_str_mv |
2010-08-23T16:58:24Z 2010-11-04T14:19:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/552 |
dc.identifier.issn.pt_BR.fl_str_mv |
0074-0276 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/S0074-02762003000200007 |
identifier_str_mv |
BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003. 0074-0276 10.1590/S0074-02762003000200007 |
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https://www.arca.fiocruz.br/handle/icict/552 |
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Fundação Oswaldo Cruz |
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Fundação Oswaldo Cruz |
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