Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals

Bibliographic Details
Main Author: Bongertz, Vera
Publication Date: 2003
Other Authors: Reis, Elaine Priscilla Ouverney, Teixeira, Sylvia Lopes Maia, Jesus, Carlos Silva de, Vilas-Boas Hacker, Mariana de Andrea, Morgado, Mariza Gonçalves, Bastos, Francisco Inácio Pinkusfeld Monteiro
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/552
Summary: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.
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spelling Bongertz, VeraReis, Elaine Priscilla OuverneyTeixeira, Sylvia Lopes MaiaJesus, Carlos Silva deVilas-Boas Hacker, Mariana de AndreaMorgado, Mariza GonçalvesBastos, Francisco Inácio Pinkusfeld Monteiro2010-08-23T16:58:24Z2010-11-04T14:19:46Z2010-08-23T16:58:24Z2010-11-04T14:19:46Z2003BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003.0074-0276https://www.arca.fiocruz.br/handle/icict/55210.1590/S0074-02762003000200007engFundação Oswaldo Cruzhuman immunodeficiency virus-1Antibodiesinjection drug usersAnti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individualsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Informação Científica e Tecnológica. Rio de Janeiro, RJ, Brasil.Sera from infected injection drug users (IDU) have shown to have antibodies against synthetic human immunodeficiency virus-1 (HIV-1) envelope peptides more frequently. In this study, reactivity of 48 IDU plasma were compared to 60 plasmas obtained from sexually infected individuals (S). The overall reactivity of plasma from IDU compared to S was higher, and the reactivity titers were much higher for IDU plasma than S. IDU plasma also showed a broader antibody response. The higher reactivity titers were observed mainly for the gp41 immunodominant epitope and V3 peptides corresponding to the consensus sequences of HIV-1 subtypes/variants prevalent in Brazil (B, F, C) indicating the specificity in the higher immune response of IDU.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZTEXTBastos_Anti-human immunodeficienty_2003.pdf.txtBastos_Anti-human immunodeficienty_2003.pdf.txtExtracted texttext/plain20024https://www.arca.fiocruz.br/bitstream/icict/552/6/Bastos_Anti-human%20immunodeficienty_2003.pdf.txtec430460fb4ef245f627bb46b515233dMD56ORIGINALBastos_Anti-human immunodeficienty_2003.pdfapplication/pdf50084https://www.arca.fiocruz.br/bitstream/icict/552/2/Bastos_Anti-human%20immunodeficienty_2003.pdf0c16dfd094c5128949ca49b80520cb9eMD52LICENSElicense.txttext/plain1841https://www.arca.fiocruz.br/bitstream/icict/552/3/license.txt1c7bab69f8f9749b10817a04ad964e54MD53THUMBNAILBastos_Anti-human immunodeficienty_2003.pdf.jpgBastos_Anti-human immunodeficienty_2003.pdf.jpgGenerated Thumbnailimage/jpeg2370https://www.arca.fiocruz.br/bitstream/icict/552/5/Bastos_Anti-human%20immunodeficienty_2003.pdf.jpg428e484b2f9a85a4a8c735189752e4d9MD55icict/5522023-09-04 11:10:59.672oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T14:10:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
title Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
spellingShingle Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
Bongertz, Vera
human immunodeficiency virus-1
Antibodies
injection drug users
title_short Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
title_full Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
title_fullStr Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
title_full_unstemmed Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
title_sort Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals
author Bongertz, Vera
author_facet Bongertz, Vera
Reis, Elaine Priscilla Ouverney
Teixeira, Sylvia Lopes Maia
Jesus, Carlos Silva de
Vilas-Boas Hacker, Mariana de Andrea
Morgado, Mariza Gonçalves
Bastos, Francisco Inácio Pinkusfeld Monteiro
author_role author
author2 Reis, Elaine Priscilla Ouverney
Teixeira, Sylvia Lopes Maia
Jesus, Carlos Silva de
Vilas-Boas Hacker, Mariana de Andrea
Morgado, Mariza Gonçalves
Bastos, Francisco Inácio Pinkusfeld Monteiro
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bongertz, Vera
Reis, Elaine Priscilla Ouverney
Teixeira, Sylvia Lopes Maia
Jesus, Carlos Silva de
Vilas-Boas Hacker, Mariana de Andrea
Morgado, Mariza Gonçalves
Bastos, Francisco Inácio Pinkusfeld Monteiro
dc.subject.por.fl_str_mv human immunodeficiency virus-1
Antibodies
injection drug users
topic human immunodeficiency virus-1
Antibodies
injection drug users
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Aids e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2010-08-23T16:58:24Z
2010-11-04T14:19:46Z
dc.date.available.fl_str_mv 2010-08-23T16:58:24Z
2010-11-04T14:19:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/552
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S0074-02762003000200007
identifier_str_mv BONGERTZ, Vera et al. Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 2, p. 209-212, mar. 2003.
0074-0276
10.1590/S0074-02762003000200007
url https://www.arca.fiocruz.br/handle/icict/552
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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