Potassium iodide capsule treatment of feline sporotrichosis

Detalhes bibliográficos
Autor(a) principal: Reis, E. G.
Data de Publicação: 2012
Outros Autores: Gremião, I. D., Kitada, A. A., Rocha, R. F., Castro, V. S., Barros, M. B. L., Menezes, R. C., Pereira, S. A., Schubach, T. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/33206
Resumo: 2020-05-24
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spelling Reis, E. G.Gremião, I. D.Kitada, A. A.Rocha, R. F.Castro, V. S.Barros, M. B. L.Menezes, R. C.Pereira, S. A.Schubach, T. M.2019-05-24T13:16:47Z2019-05-24T13:16:47Z2012REIS, Érica G. et al. Potassium iodide capsule treatment of feline sporotrichosis. Journal of Feline Medicine and Surgery, v. 14, n. 6, p. 399-404, 2012.1098-612Xhttps://www.arca.fiocruz.br/handle/icict/3320610.1177/1098612X124413171532-2750engSAGE PublicationsPotassium iodide capsule treatment of feline sporotrichosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-05-24Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Federal University of Santa Maria. Veterinary Hospital. Department of Small Animals. Santa Maria, RS, Brazil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos. Rio de Janeiro, RJ, Brasil.Sporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.SporotrichosisFeline sporotrichosisTreatmentPotassium iodide capsuleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33206/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Reis_Érica_etal_INI_2012.pdfve_Reis_Érica_etal_INI_2012.pdfapplication/pdf377003https://www.arca.fiocruz.br/bitstream/icict/33206/2/ve_Reis_%c3%89rica_etal_INI_2012.pdf0df208aee9059909e37d696c259c4d25MD52TEXTve_Reis_Érica_etal_INI_2012.pdf.txtve_Reis_Érica_etal_INI_2012.pdf.txtExtracted texttext/plain22984https://www.arca.fiocruz.br/bitstream/icict/33206/3/ve_Reis_%c3%89rica_etal_INI_2012.pdf.txtd827bedccb440a1b55e5a26fa4d96fd2MD53icict/332062021-03-24 16:32:32.014oai:www.arca.fiocruz.br:icict/33206Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:32Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Potassium iodide capsule treatment of feline sporotrichosis
title Potassium iodide capsule treatment of feline sporotrichosis
spellingShingle Potassium iodide capsule treatment of feline sporotrichosis
Reis, E. G.
Sporotrichosis
Feline sporotrichosis
Treatment
Potassium iodide capsule
title_short Potassium iodide capsule treatment of feline sporotrichosis
title_full Potassium iodide capsule treatment of feline sporotrichosis
title_fullStr Potassium iodide capsule treatment of feline sporotrichosis
title_full_unstemmed Potassium iodide capsule treatment of feline sporotrichosis
title_sort Potassium iodide capsule treatment of feline sporotrichosis
author Reis, E. G.
author_facet Reis, E. G.
Gremião, I. D.
Kitada, A. A.
Rocha, R. F.
Castro, V. S.
Barros, M. B. L.
Menezes, R. C.
Pereira, S. A.
Schubach, T. M.
author_role author
author2 Gremião, I. D.
Kitada, A. A.
Rocha, R. F.
Castro, V. S.
Barros, M. B. L.
Menezes, R. C.
Pereira, S. A.
Schubach, T. M.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reis, E. G.
Gremião, I. D.
Kitada, A. A.
Rocha, R. F.
Castro, V. S.
Barros, M. B. L.
Menezes, R. C.
Pereira, S. A.
Schubach, T. M.
dc.subject.en.pt_BR.fl_str_mv Sporotrichosis
Feline sporotrichosis
Treatment
Potassium iodide capsule
topic Sporotrichosis
Feline sporotrichosis
Treatment
Potassium iodide capsule
description 2020-05-24
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2019-05-24T13:16:47Z
dc.date.available.fl_str_mv 2019-05-24T13:16:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv REIS, Érica G. et al. Potassium iodide capsule treatment of feline sporotrichosis. Journal of Feline Medicine and Surgery, v. 14, n. 6, p. 399-404, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33206
dc.identifier.issn.pt_BR.fl_str_mv 1098-612X
dc.identifier.doi.none.fl_str_mv 10.1177/1098612X12441317
dc.identifier.eissn.none.fl_str_mv 1532-2750
identifier_str_mv REIS, Érica G. et al. Potassium iodide capsule treatment of feline sporotrichosis. Journal of Feline Medicine and Surgery, v. 14, n. 6, p. 399-404, 2012.
1098-612X
10.1177/1098612X12441317
1532-2750
url https://www.arca.fiocruz.br/handle/icict/33206
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv SAGE Publications
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