Decoding the Role of Glycans in Malaria

Detalhes bibliográficos
Autor(a) principal: Gomes, Pollyanna Stephanie
Data de Publicação: 2017
Outros Autores: Feijó, Daniel Ferreira, Morrot, Alexandre, Freire-de-Lima, Celio Geraldo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/20036
Resumo: Conselho Nacional de Desenvolvimento Científico e Tecnológico do Brasil (CNPq) and the Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ).
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spelling Gomes, Pollyanna StephanieFeijó, Daniel FerreiraMorrot, AlexandreFreire-de-Lima, Celio Geraldo2017-07-11T12:43:47Z2017-07-11T12:43:47Z2017GOMES, Pollyanna Stephanie et al. Decoding the Role of Glycans in Malaria. Frontiers in Microbiology, v. 8, Article 1071, p. 1-12, June 2017.1664-302Xhttps://www.arca.fiocruz.br/handle/icict/2003610.3389/fmicb.2017.01071Conselho Nacional de Desenvolvimento Científico e Tecnológico do Brasil (CNPq) and the Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ).Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Departamento de Imunologia. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilUniversidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Rio de Janeiro, RJ, BrasilComplications arising from malaria are a concern for public health authorities worldwide, since the annual caseload in humans usually exceeds millions. Of more than 160 species of Plasmodium, only 4 infect humans, with the most severe cases ascribed to Plasmodium falciparum and the most prevalent to Plasmodium vivax. Over the past 70 years, since World War II, when the first antimalarial drugs were widely used, many efforts have been made to combat this disease, including vectorial control, new drug discoveries and genetic and molecular approaches. Molecular approaches, such as glycobiology, may lead to new therapeutic targets (both in the host and the parasites), since all interactions are mediated by carbohydrates or glycan moieties decorating both cellular surfaces from parasite and host cells. In this review, we address the carbohydrate-mediated glycobiology that directly affects Plasmodium survival or host resistance.porFrontiers Research FoundationMaláriaGlicobiologiaAlvos de carboidratosPlasmodium falciparumMalariaGlycobiologyCarbohydrate-targetsPlasmodium falciparumDecoding the Role of Glycans in Malariainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/20036/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALGomes PS Decoding the role....pdfGomes PS Decoding the role....pdfapplication/pdf318761https://www.arca.fiocruz.br/bitstream/icict/20036/2/Gomes%20PS%20Decoding%20the%20role....pdf7b7f10672cf6d1dfc4189dd62df4d2f3MD52TEXTGomes PS Decoding the role....pdf.txtGomes PS Decoding the role....pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Decoding the Role of Glycans in Malaria
title Decoding the Role of Glycans in Malaria
spellingShingle Decoding the Role of Glycans in Malaria
Gomes, Pollyanna Stephanie
Malária
Glicobiologia
Alvos de carboidratos
Plasmodium falciparum
Malaria
Glycobiology
Carbohydrate-targets
Plasmodium falciparum
title_short Decoding the Role of Glycans in Malaria
title_full Decoding the Role of Glycans in Malaria
title_fullStr Decoding the Role of Glycans in Malaria
title_full_unstemmed Decoding the Role of Glycans in Malaria
title_sort Decoding the Role of Glycans in Malaria
author Gomes, Pollyanna Stephanie
author_facet Gomes, Pollyanna Stephanie
Feijó, Daniel Ferreira
Morrot, Alexandre
Freire-de-Lima, Celio Geraldo
author_role author
author2 Feijó, Daniel Ferreira
Morrot, Alexandre
Freire-de-Lima, Celio Geraldo
author2_role author
author
author
dc.contributor.author.fl_str_mv Gomes, Pollyanna Stephanie
Feijó, Daniel Ferreira
Morrot, Alexandre
Freire-de-Lima, Celio Geraldo
dc.subject.other.pt_BR.fl_str_mv Malária
Glicobiologia
Alvos de carboidratos
Plasmodium falciparum
topic Malária
Glicobiologia
Alvos de carboidratos
Plasmodium falciparum
Malaria
Glycobiology
Carbohydrate-targets
Plasmodium falciparum
dc.subject.en.pt_BR.fl_str_mv Malaria
Glycobiology
Carbohydrate-targets
Plasmodium falciparum
description Conselho Nacional de Desenvolvimento Científico e Tecnológico do Brasil (CNPq) and the Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ).
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-07-11T12:43:47Z
dc.date.available.fl_str_mv 2017-07-11T12:43:47Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMES, Pollyanna Stephanie et al. Decoding the Role of Glycans in Malaria. Frontiers in Microbiology, v. 8, Article 1071, p. 1-12, June 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/20036
dc.identifier.issn.pt_BR.fl_str_mv 1664-302X
dc.identifier.doi.none.fl_str_mv 10.3389/fmicb.2017.01071
identifier_str_mv GOMES, Pollyanna Stephanie et al. Decoding the Role of Glycans in Malaria. Frontiers in Microbiology, v. 8, Article 1071, p. 1-12, June 2017.
1664-302X
10.3389/fmicb.2017.01071
url https://www.arca.fiocruz.br/handle/icict/20036
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dc.publisher.none.fl_str_mv Frontiers Research Foundation
publisher.none.fl_str_mv Frontiers Research Foundation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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