The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study

Detalhes bibliográficos
Autor(a) principal: Skacel, Michael
Data de Publicação: 2000
Outros Autores: Antunes, Sérgio Luiz Gomes, Rodrigues, Márcia Maria Jardim, Nery, José Augusto da Costa, Valentim, Vânia da Costa, Morais, Renara Patrícia Braga de, Sarno, Euzenir Nunes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/33286
Resumo: Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença.
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spelling Skacel, MichaelAntunes, Sérgio Luiz GomesRodrigues, Márcia Maria JardimNery, José Augusto da CostaValentim, Vânia da CostaMorais, Renara Patrícia Braga deSarno, Euzenir Nunes2019-05-30T13:01:37Z2019-05-30T13:01:37Z2000SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000.0004-282Xhttps://www.arca.fiocruz.br/handle/icict/3328610.1590/S0004-282X20000005000021678-4227Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença.Forty-four patients with neuritic leprosy were individually followed for periods ranging from 4 months to almost 4 years for the purpose of ascertaining the presence and/ or absence of leprosy. The neural symptoms presented were sensory impairment (41), parasthesia (28), nerve enlargement (22), nerve tenderness (20), paresia (20), amyotrophy (8). Leprosy was diagnosed in ten out of the total number of patients studied. Leprosy was confirmed by the appearance of reactional neuritis (4), reversal reaction (2), biopsy of the hypoesthesic area (3) and the appearance of non-reactional cutaneous lesion. We reported an experience in the diagnosis of neuritic leprosy and its most frequent clinical presentation with which clinicians have to be acquainted. We can also state that the clinical follow-up was an effective strategy for the diagnosis of the disease when diagnostic facilities are not available or have not confirmed the diagnosis.Universidade do Estado do Rio de Janeiro. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil / Universidade Iguaçu. Disciplina de Patologia. Nova Iguaçu, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. 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dc.title.pt_BR.fl_str_mv The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
dc.title.alternative.pt_BR.fl_str_mv O diagnóstico de hanseníase neural pura entre pacientes com sintomas de neuropatia periférica: acompanhamento clínico
title The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
spellingShingle The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
Skacel, Michael
Hanseníase
Neurite
Neuropatia periférica
Leprosy
Neuritic leprosy
Peripheral neuropathy
title_short The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
title_full The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
title_fullStr The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
title_full_unstemmed The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
title_sort The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
author Skacel, Michael
author_facet Skacel, Michael
Antunes, Sérgio Luiz Gomes
Rodrigues, Márcia Maria Jardim
Nery, José Augusto da Costa
Valentim, Vânia da Costa
Morais, Renara Patrícia Braga de
Sarno, Euzenir Nunes
author_role author
author2 Antunes, Sérgio Luiz Gomes
Rodrigues, Márcia Maria Jardim
Nery, José Augusto da Costa
Valentim, Vânia da Costa
Morais, Renara Patrícia Braga de
Sarno, Euzenir Nunes
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Skacel, Michael
Antunes, Sérgio Luiz Gomes
Rodrigues, Márcia Maria Jardim
Nery, José Augusto da Costa
Valentim, Vânia da Costa
Morais, Renara Patrícia Braga de
Sarno, Euzenir Nunes
dc.subject.other.pt_BR.fl_str_mv Hanseníase
Neurite
Neuropatia periférica
topic Hanseníase
Neurite
Neuropatia periférica
Leprosy
Neuritic leprosy
Peripheral neuropathy
dc.subject.en.pt_BR.fl_str_mv Leprosy
Neuritic leprosy
Peripheral neuropathy
description Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença.
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2019-05-30T13:01:37Z
dc.date.available.fl_str_mv 2019-05-30T13:01:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33286
dc.identifier.issn.pt_BR.fl_str_mv 0004-282X
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S0004-282X2000000500002
dc.identifier.eissn.none.fl_str_mv 1678-4227
identifier_str_mv SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000.
0004-282X
10.1590/S0004-282X2000000500002
1678-4227
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dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia
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