The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/33286 |
Resumo: | Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença. |
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Skacel, MichaelAntunes, Sérgio Luiz GomesRodrigues, Márcia Maria JardimNery, José Augusto da CostaValentim, Vânia da CostaMorais, Renara Patrícia Braga deSarno, Euzenir Nunes2019-05-30T13:01:37Z2019-05-30T13:01:37Z2000SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000.0004-282Xhttps://www.arca.fiocruz.br/handle/icict/3328610.1590/S0004-282X20000005000021678-4227Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença.Forty-four patients with neuritic leprosy were individually followed for periods ranging from 4 months to almost 4 years for the purpose of ascertaining the presence and/ or absence of leprosy. The neural symptoms presented were sensory impairment (41), parasthesia (28), nerve enlargement (22), nerve tenderness (20), paresia (20), amyotrophy (8). Leprosy was diagnosed in ten out of the total number of patients studied. Leprosy was confirmed by the appearance of reactional neuritis (4), reversal reaction (2), biopsy of the hypoesthesic area (3) and the appearance of non-reactional cutaneous lesion. We reported an experience in the diagnosis of neuritic leprosy and its most frequent clinical presentation with which clinicians have to be acquainted. We can also state that the clinical follow-up was an effective strategy for the diagnosis of the disease when diagnostic facilities are not available or have not confirmed the diagnosis.Universidade do Estado do Rio de Janeiro. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil / Universidade Iguaçu. Disciplina de Patologia. Nova Iguaçu, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ, Brasil.engAcademia Brasileira de NeurologiaHanseníaseNeuriteNeuropatia periféricaLeprosyNeuritic leprosyPeripheral neuropathyThe diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up studyO diagnóstico de hanseníase neural pura entre pacientes com sintomas de neuropatia periférica: acompanhamento clínicoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
dc.title.alternative.pt_BR.fl_str_mv |
O diagnóstico de hanseníase neural pura entre pacientes com sintomas de neuropatia periférica: acompanhamento clínico |
title |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
spellingShingle |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study Skacel, Michael Hanseníase Neurite Neuropatia periférica Leprosy Neuritic leprosy Peripheral neuropathy |
title_short |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
title_full |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
title_fullStr |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
title_full_unstemmed |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
title_sort |
The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study |
author |
Skacel, Michael |
author_facet |
Skacel, Michael Antunes, Sérgio Luiz Gomes Rodrigues, Márcia Maria Jardim Nery, José Augusto da Costa Valentim, Vânia da Costa Morais, Renara Patrícia Braga de Sarno, Euzenir Nunes |
author_role |
author |
author2 |
Antunes, Sérgio Luiz Gomes Rodrigues, Márcia Maria Jardim Nery, José Augusto da Costa Valentim, Vânia da Costa Morais, Renara Patrícia Braga de Sarno, Euzenir Nunes |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Skacel, Michael Antunes, Sérgio Luiz Gomes Rodrigues, Márcia Maria Jardim Nery, José Augusto da Costa Valentim, Vânia da Costa Morais, Renara Patrícia Braga de Sarno, Euzenir Nunes |
dc.subject.other.pt_BR.fl_str_mv |
Hanseníase Neurite Neuropatia periférica |
topic |
Hanseníase Neurite Neuropatia periférica Leprosy Neuritic leprosy Peripheral neuropathy |
dc.subject.en.pt_BR.fl_str_mv |
Leprosy Neuritic leprosy Peripheral neuropathy |
description |
Quarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença. |
publishDate |
2000 |
dc.date.issued.fl_str_mv |
2000 |
dc.date.accessioned.fl_str_mv |
2019-05-30T13:01:37Z |
dc.date.available.fl_str_mv |
2019-05-30T13:01:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/33286 |
dc.identifier.issn.pt_BR.fl_str_mv |
0004-282X |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/S0004-282X2000000500002 |
dc.identifier.eissn.none.fl_str_mv |
1678-4227 |
identifier_str_mv |
SKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000. 0004-282X 10.1590/S0004-282X2000000500002 1678-4227 |
url |
https://www.arca.fiocruz.br/handle/icict/33286 |
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eng |
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eng |
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openAccess |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia |
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