Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain

Detalhes bibliográficos
Autor(a) principal: Pacheco, Raquel S.
Data de Publicação: 1998
Outros Autores: Ferreira, Marcelo S., Machado, Maria Inês, Brito, Célia M. M., Pires, Marize Q., Cruz, Alda M. da, Coutinho, Sergio G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43924
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
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spelling Pacheco, Raquel S.Ferreira, Marcelo S.Machado, Maria InêsBrito, Célia M. M.Pires, Marize Q.Cruz, Alda M. daCoutinho, Sergio G.2020-10-11T20:23:31Z2020-10-11T20:23:31Z1998PACHECO, Raquel S. et al. Chagas' Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, n. 2, p. 185-169, Mar./Apr. 1998.0074-0276https://www.arca.fiocruz.br/handle/icict/4392410.1590/S0074-027619980002000051678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Doença de ChagasTrypanosoma cruziInfecção oportunistaCo-infecção por AIDSReativaçãoChagas’ diseaseAIDS co-infectionOpportunistic infectionTrypanosoma cruziReactivationChagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Straininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal de Uberlândia. Departamento de Patologia. Uberlândia, MG, Brasil.Universidade Federal de Uberlândia. Departamento de Patologia. Uberlândia, MG, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Publica Sérgio Arouca. Departamento de Ciências Biológicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Rio de Janeiro, RJ, Brasil.In the past few years, new aspects of the immunopathology of Chagas’ disease have been described in immunosuppressed patients, such as fatal central nervous system lesions related to the reactivation of the parasite. This article is the first description of the genotypic characterization, at the strain level, of Trypanosoma cruzi isolated from a patient with Chagas‘ disease/AIDS co-infection. The presence of four hypodense lesions was observed in the cranial compute tomographic scan. The diagnosis of AIDS was assessed by the detection of anti-HIV antibodies using enzyme-linked immunosorbent assay (ELISA) and Western blot techniques. The CD4+ lymphocyte counts were maintained under 200 cells/mm3 during one year demonstrating the severity of the state of immunosuppression. Chagas’ disease was confirmed by serological and parasitological methods. Trypomastigote forms were visualized in a thick blood smear. The parasite isolated is genotypically similar to the CL strain. 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dc.title.pt_BR.fl_str_mv Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
title Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
spellingShingle Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
Pacheco, Raquel S.
Doença de Chagas
Trypanosoma cruzi
Infecção oportunista
Co-infecção por AIDS
Reativação
Chagas’ disease
AIDS co-infection
Opportunistic infection
Trypanosoma cruzi
Reactivation
title_short Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
title_full Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
title_fullStr Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
title_full_unstemmed Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
title_sort Chagas Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
author Pacheco, Raquel S.
author_facet Pacheco, Raquel S.
Ferreira, Marcelo S.
Machado, Maria Inês
Brito, Célia M. M.
Pires, Marize Q.
Cruz, Alda M. da
Coutinho, Sergio G.
author_role author
author2 Ferreira, Marcelo S.
Machado, Maria Inês
Brito, Célia M. M.
Pires, Marize Q.
Cruz, Alda M. da
Coutinho, Sergio G.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pacheco, Raquel S.
Ferreira, Marcelo S.
Machado, Maria Inês
Brito, Célia M. M.
Pires, Marize Q.
Cruz, Alda M. da
Coutinho, Sergio G.
dc.subject.other.pt_BR.fl_str_mv Doença de Chagas
Trypanosoma cruzi
Infecção oportunista
Co-infecção por AIDS
Reativação
topic Doença de Chagas
Trypanosoma cruzi
Infecção oportunista
Co-infecção por AIDS
Reativação
Chagas’ disease
AIDS co-infection
Opportunistic infection
Trypanosoma cruzi
Reactivation
dc.subject.en.pt_BR.fl_str_mv Chagas’ disease
AIDS co-infection
Opportunistic infection
Trypanosoma cruzi
Reactivation
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
publishDate 1998
dc.date.issued.fl_str_mv 1998
dc.date.accessioned.fl_str_mv 2020-10-11T20:23:31Z
dc.date.available.fl_str_mv 2020-10-11T20:23:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv PACHECO, Raquel S. et al. Chagas' Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, n. 2, p. 185-169, Mar./Apr. 1998.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43924
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761998000200005
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv PACHECO, Raquel S. et al. Chagas' Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, n. 2, p. 185-169, Mar./Apr. 1998.
0074-0276
10.1590/S0074-02761998000200005
1678-8060
url https://www.arca.fiocruz.br/handle/icict/43924
dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
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