Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/23485 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil. |
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Rebouças, M. C.Guerreiro, Marcos Lázaro da SilvaAndrade, Sonia Gumes2017-11-30T17:04:53Z2017-11-30T17:04:53Z2012REBOUÇAS, M. C.; GUERREIRO, Marcos Lázaro da Silva; ANDRADE, Sonia Gumes. Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18.; CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. 1 p.https://www.arca.fiocruz.br/handle/icict/23485engSociedade Brasileira de Medicina TropicalTrypanosoma cruziDoença de ChagasQuimioterapiaCamundogosInfecçãoTrypanosoma cruziChagas diseaseChemotherapyMiceInfectionEvaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil.Introduction: People living in endemic areas of Chagas disease are submitted to multiple infections during their lives and could be infected with strains or clones with different virulence and susceptibility to chemotherapy. This is an important factor in the development and morbidity of the disease. Strains of Trypanosoma cruzi represent complex multiclonal populations, which can be homogeneous or heterogeneous with predominance of a principal clone. The strains are biologically classified in different Biodemes (Types I, II and III) which disclose different degrees of resistance to chemotherapy. Type I strains are very susceptible to treatment. Type II strains disclose medium susceptibility (21SF strain); strains of Type III are very resistant (Colombian strain). The clones isolated from different strains can also present different degrees of resistance. In the present study the results of treatment of mice triple infected with clones of the 21SF strain is evaluated, in comparison with the infected with the parental strain.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/23485/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALChag12 Reboucas MC Evaluation of the... SBMT 2012.pdfChag12 Reboucas MC Evaluation of the... SBMT 2012.pdfapplication/pdf94929https://www.arca.fiocruz.br/bitstream/icict/23485/2/Chag12%20Reboucas%20MC%20Evaluation%20of%20the...%20SBMT%202012.pdf14dde42d412319cf80311e8613e49794MD52TEXTChag12 Reboucas MC Evaluation of the... SBMT 2012.pdf.txtChag12 Reboucas MC Evaluation of the... SBMT 2012.pdf.txtExtracted texttext/plain3035https://www.arca.fiocruz.br/bitstream/icict/23485/3/Chag12%20Reboucas%20MC%20Evaluation%20of%20the...%20SBMT%202012.pdf.txt150ac45d09d0f6204d56d155391fb670MD53icict/234852019-07-10 20:21:56.976oai:www.arca.fiocruz.br:icict/23485Q0VTU8ODTyBOw4NPIEVYQ0xVU0lWQSBERSBESVJFSVRPUyBBVVRPUkFJUwoKQW8gYWNlaXRhciBvcyBURVJNT1MgZSBDT05EScOHw5VFUyBkZXN0YSBDRVNTw4NPLCBvIEFVVE9SIGUvb3UgVElUVUxBUiBkZSBkaXJlaXRvcwphdXRvcmFpcyBzb2JyZSBhIE9CUkEgZGUgcXVlIHRyYXRhIGVzdGUgZG9jdW1lbnRvOgoKKDEpIENFREUgZSBUUkFOU0ZFUkUsIHRvdGFsIGUgZ3JhdHVpdGFtZW50ZSwgw6AgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaLCBlbQpjYXLDoXRlciBwZXJtYW5lbnRlLCBpcnJldm9nw6F2ZWwgZSBOw4NPIEVYQ0xVU0lWTywgdG9kb3Mgb3MgZGlyZWl0b3MgcGF0cmltb25pYWlzIE7Dg08KQ09NRVJDSUFJUyBkZSB1dGlsaXphw6fDo28gZGEgT0JSQSBhcnTDrXN0aWNhIGUvb3UgY2llbnTDrWZpY2EgaW5kaWNhZGEgYWNpbWEsIGluY2x1c2l2ZSBvcyBkaXJlaXRvcwpkZSB2b3ogZSBpbWFnZW0gdmluY3VsYWRvcyDDoCBPQlJBLCBkdXJhbnRlIHRvZG8gbyBwcmF6byBkZSBkdXJhw6fDo28gZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBlbQpxdWFscXVlciBpZGlvbWEgZSBlbSB0b2RvcyBvcyBwYcOtc2VzOwoKKDIpIEFDRUlUQSBxdWUgYSBjZXNzw6NvIHRvdGFsIG7Do28gZXhjbHVzaXZhLCBwZXJtYW5lbnRlIGUgaXJyZXZvZ8OhdmVsIGRvcyBkaXJlaXRvcyBhdXRvcmFpcwpwYXRyaW1vbmlhaXMgbsOjbyBjb21lcmNpYWlzIGRlIHV0aWxpemHDp8OjbyBkZSBxdWUgdHJhdGEgZXN0ZSBkb2N1bWVudG8gaW5jbHVpLCBleGVtcGxpZmljYXRpdmFtZW50ZSwKb3MgZGlyZWl0b3MgZGUgZGlzcG9uaWJpbGl6YcOnw6NvIGUgY29tdW5pY2HDp8OjbyBww7pibGljYSBkYSBPQlJBLCBlbSBxdWFscXVlciBtZWlvIG91IHZlw61jdWxvLAppbmNsdXNpdmUgZW0gUmVwb3NpdMOzcmlvcyBEaWdpdGFpcywgYmVtIGNvbW8gb3MgZGlyZWl0b3MgZGUgcmVwcm9kdcOnw6NvLCBleGliacOnw6NvLCBleGVjdcOnw6NvLApkZWNsYW1hw6fDo28sIHJlY2l0YcOnw6NvLCBleHBvc2nDp8OjbywgYXJxdWl2YW1lbnRvLCBpbmNsdXPDo28gZW0gYmFuY28gZGUgZGFkb3MsIHByZXNlcnZhw6fDo28sIGRpZnVzw6NvLApkaXN0cmlidWnDp8OjbywgZGl2dWxnYcOnw6NvLCBlbXByw6lzdGltbywgdHJhZHXDp8OjbywgZHVibGFnZW0sIGxlZ2VuZGFnZW0sIGluY2x1c8OjbyBlbSBub3ZhcyBvYnJhcyBvdQpjb2xldMOibmVhcywgcmV1dGlsaXphw6fDo28sIGVkacOnw6NvLCBwcm9kdcOnw6NvIGRlIG1hdGVyaWFsIGRpZMOhdGljbyBlIGN1cnNvcyBvdSBxdWFscXVlciBmb3JtYSBkZQp1dGlsaXphw6fDo28gbsOjbyBjb21lcmNpYWw7CgooMykgUkVDT05IRUNFIHF1ZSBhIGNlc3PDo28gYXF1aSBlc3BlY2lmaWNhZGEgY29uY2VkZSDDoCBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPCkNSVVogbyBkaXJlaXRvIGRlIGF1dG9yaXphciBxdWFscXVlciBwZXNzb2Eg4oCTIGbDrXNpY2Egb3UganVyw61kaWNhLCBww7pibGljYSBvdSBwcml2YWRhLCBuYWNpb25hbCBvdQplc3RyYW5nZWlyYSDigJMgYSBhY2Vzc2FyIGUgdXRpbGl6YXIgYW1wbGFtZW50ZSBhIE9CUkEsIHNlbSBleGNsdXNpdmlkYWRlLCBwYXJhIHF1YWlzcXVlcgpmaW5hbGlkYWRlcyBuw6NvIGNvbWVyY2lhaXM7CgooNCkgREVDTEFSQSBxdWUgYSBvYnJhIMOpIGNyaWHDp8OjbyBvcmlnaW5hbCBlIHF1ZSDDqSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGFxdWkgY2VkaWRvcyBlIGF1dG9yaXphZG9zLApyZXNwb25zYWJpbGl6YW5kby1zZSBpbnRlZ3JhbG1lbnRlIHBlbG8gY29udGXDumRvIGUgb3V0cm9zIGVsZW1lbnRvcyBxdWUgZmF6ZW0gcGFydGUgZGEgT0JSQSwKaW5jbHVzaXZlIG9zIGRpcmVpdG9zIGRlIHZveiBlIGltYWdlbSB2aW5jdWxhZG9zIMOgIE9CUkEsIG9icmlnYW5kby1zZSBhIGluZGVuaXphciB0ZXJjZWlyb3MgcG9yCmRhbm9zLCBiZW0gY29tbyBpbmRlbml6YXIgZSByZXNzYXJjaXIgYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVogZGUKZXZlbnR1YWlzIGRlc3Blc2FzIHF1ZSB2aWVyZW0gYSBzdXBvcnRhciwgZW0gcmF6w6NvIGRlIHF1YWxxdWVyIG9mZW5zYSBhIGRpcmVpdG9zIGF1dG9yYWlzIG91CmRpcmVpdG9zIGRlIHZveiBvdSBpbWFnZW0sIHByaW5jaXBhbG1lbnRlIG5vIHF1ZSBkaXogcmVzcGVpdG8gYSBwbMOhZ2lvIGUgdmlvbGHDp8O1ZXMgZGUgZGlyZWl0b3M7CgooNSkgQUZJUk1BIHF1ZSBjb25oZWNlIGEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTwpPU1dBTERPIENSVVogZSBhcyBkaXJldHJpemVzIHBhcmEgbyBmdW5jaW9uYW1lbnRvIGRvIHJlcG9zaXTDs3JpbyBpbnN0aXR1Y2lvbmFsIEFSQ0EuCgpBIFBvbMOtdGljYSBJbnN0aXR1Y2lvbmFsIGRlIEFjZXNzbyBBYmVydG8gZGEgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaIHJlc2VydmEKZXhjbHVzaXZhbWVudGUgYW8gQVVUT1Igb3MgZGlyZWl0b3MgbW9yYWlzIGUgb3MgdXNvcyBjb21lcmNpYWlzIHNvYnJlIGFzIG9icmFzIGRlIHN1YSBhdXRvcmlhCmUvb3UgdGl0dWxhcmlkYWRlLCBzZW5kbyBvcyB0ZXJjZWlyb3MgdXN1w6FyaW9zIHJlc3BvbnPDoXZlaXMgcGVsYSBhdHJpYnVpw6fDo28gZGUgYXV0b3JpYSBlIG1hbnV0ZW7Dp8OjbwpkYSBpbnRlZ3JpZGFkZSBkYSBPQlJBIGVtIHF1YWxxdWVyIHV0aWxpemHDp8Ojby4KCkEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVoKcmVzcGVpdGEgb3MgY29udHJhdG9zIGUgYWNvcmRvcyBwcmVleGlzdGVudGVzIGRvcyBBdXRvcmVzIGNvbSB0ZXJjZWlyb3MsIGNhYmVuZG8gYW9zIEF1dG9yZXMKaW5mb3JtYXIgw6AgSW5zdGl0dWnDp8OjbyBhcyBjb25kacOnw7VlcyBlIG91dHJhcyByZXN0cmnDp8O1ZXMgaW1wb3N0YXMgcG9yIGVzdGVzIGluc3RydW1lbnRvcy4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-07-10T23:21:56Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
title |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
spellingShingle |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection Rebouças, M. C. Trypanosoma cruzi Doença de Chagas Quimioterapia Camundogos Infecção Trypanosoma cruzi Chagas disease Chemotherapy Mice Infection |
title_short |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
title_full |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
title_fullStr |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
title_full_unstemmed |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
title_sort |
Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection |
author |
Rebouças, M. C. |
author_facet |
Rebouças, M. C. Guerreiro, Marcos Lázaro da Silva Andrade, Sonia Gumes |
author_role |
author |
author2 |
Guerreiro, Marcos Lázaro da Silva Andrade, Sonia Gumes |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Rebouças, M. C. Guerreiro, Marcos Lázaro da Silva Andrade, Sonia Gumes |
dc.subject.other.pt_BR.fl_str_mv |
Trypanosoma cruzi Doença de Chagas Quimioterapia Camundogos Infecção |
topic |
Trypanosoma cruzi Doença de Chagas Quimioterapia Camundogos Infecção Trypanosoma cruzi Chagas disease Chemotherapy Mice Infection |
dc.subject.en.pt_BR.fl_str_mv |
Trypanosoma cruzi Chagas disease Chemotherapy Mice Infection |
description |
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2017-11-30T17:04:53Z |
dc.date.available.fl_str_mv |
2017-11-30T17:04:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
REBOUÇAS, M. C.; GUERREIRO, Marcos Lázaro da Silva; ANDRADE, Sonia Gumes. Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18.; CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. 1 p. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/23485 |
identifier_str_mv |
REBOUÇAS, M. C.; GUERREIRO, Marcos Lázaro da Silva; ANDRADE, Sonia Gumes. Evaluation of the response to treatment with Benznidazole of mice with triple infection with clones 0f 21SF strain (S. FELIPE-BA) of Trypanosoma Cruzi with different degrees of susceptibility to chemotherapy in comparison with mice with single infection. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18.; CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. 1 p. |
url |
https://www.arca.fiocruz.br/handle/icict/23485 |
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eng |
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eng |
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openAccess |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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