A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/13668 |
Resumo: | University of Queensland. School of Biological Sciences. Brisbane, Australia/ Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil |
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Moreira, Luciano AndradeIturbe-Ormaetxe, IñakiJeffery, Jason A.Lu, GuangjinPyke, Alyssa T.Hedges, Lauren M.Rocha, Bruno CoelhoHall-Mendelin, SonjaDay, AndrewRiegler, MarkusHugo, Leon E.Johnson, Karyn N.Kay, Brian H.McGraw, Elizabeth A.Hurk, Andrew F. van denRyan, Peter A.O'Neill, Scott L.2016-04-11T14:11:58Z2016-04-11T14:11:58Z2009MOREIRA, Luciano Andrade et al. A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium. Cell., vol.139, n. 7, p. 1268-78, 2009.0092-8674https://www.arca.fiocruz.br/handle/icict/1366810.1016/j.cell.2009.11.042engCell PressA Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodiuminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity of Queensland. School of Biological Sciences. Brisbane, Australia/ Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrasilUniversity of Queensland. School of Biological Sciences. Brisbane, AustraliaQueensland Institute of Medical Research. Post Office Royal Brisbane Hospital. Brisbane, AustraliaQueensland Institute of Medical Research. Post Office Royal Brisbane Hospital. Brisbane, AustraliaVirology, Queensland Health Forensic and Scientific Services. Coopers Plains, AustraliaUniversity of Queensland. School of Biological Sciences. Brisbane, AustraliaFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrasilUniversity of Queensland. School of Chemical and Molecular Biosciences. Brisbane, AustraliaUniversity of Queensland. School of Chemical and Molecular Biosciences. Brisbane, AustraliaUniversity of Queensland. School of Biological Sciences. Brisbane, Australia/University of Western Sydney. Centre for Plants and the Environment, School of Natural Sciences. Penrith South DC, NSW, AustraliaQueensland Institute of Medical Research. Post Office Royal Brisbane Hospital. Brisbane, AustraliaUniversity of Queensland. School of Biological Sciences. Brisbane, AustraliaQueensland Institute of Medical Research. Post Office Royal Brisbane Hospital. Brisbane, AustraliaUniversity of Queensland. School of Biological Sciences. Brisbane, AustraliaVirology, Queensland Health Forensic and Scientific Services. Coopers Plains, Australia/niversity of Queensland. School of Chemical and Molecular Biosciences. Brisbane, AustraliaQueensland Institute of Medical Research. Post Office Royal Brisbane Hospital. Brisbane, AustraliaUniversity of Queensland. School of Biological Sciences. Brisbane, AustraliaWolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect species. While Wolbachia is commonly found in many mosquitoes it is absent from the species that are considered to be of major importance for the transmission of human pathogens. The successful introduction of a life-shortening strain of Wolbachia into the dengue vector Aedes aegypti that halves adult lifespan has recently been reported. Here we show that this same Wolbachia infection also directly inhibits the ability of a range of pathogens to infect this mosquito species. The effect is Wolbachia strain specific and relates to Wolbachia priming of the mosquito innate immune system and potentially competition for limiting cellular resources required for pathogen replication. We suggest that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases.HumdiseaseMolimmunoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13668/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALA Wolbachia Symbiont in Aedes aegypti.pdfA Wolbachia Symbiont in Aedes aegypti.pdfapplication/pdf593492https://www.arca.fiocruz.br/bitstream/icict/13668/2/A%20Wolbachia%20Symbiont%20in%20Aedes%20aegypti.pdf0238552be9d05f0a9b2df2d52b2392f9MD52TEXTA Wolbachia Symbiont in Aedes aegypti.pdf.txtA Wolbachia Symbiont in Aedes aegypti.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| title |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| spellingShingle |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium Moreira, Luciano Andrade Humdisease Molimmuno |
| title_short |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| title_full |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| title_fullStr |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| title_full_unstemmed |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| title_sort |
A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium |
| author |
Moreira, Luciano Andrade |
| author_facet |
Moreira, Luciano Andrade Iturbe-Ormaetxe, Iñaki Jeffery, Jason A. Lu, Guangjin Pyke, Alyssa T. Hedges, Lauren M. Rocha, Bruno Coelho Hall-Mendelin, Sonja Day, Andrew Riegler, Markus Hugo, Leon E. Johnson, Karyn N. Kay, Brian H. McGraw, Elizabeth A. Hurk, Andrew F. van den Ryan, Peter A. O'Neill, Scott L. |
| author_role |
author |
| author2 |
Iturbe-Ormaetxe, Iñaki Jeffery, Jason A. Lu, Guangjin Pyke, Alyssa T. Hedges, Lauren M. Rocha, Bruno Coelho Hall-Mendelin, Sonja Day, Andrew Riegler, Markus Hugo, Leon E. Johnson, Karyn N. Kay, Brian H. McGraw, Elizabeth A. Hurk, Andrew F. van den Ryan, Peter A. O'Neill, Scott L. |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Moreira, Luciano Andrade Iturbe-Ormaetxe, Iñaki Jeffery, Jason A. Lu, Guangjin Pyke, Alyssa T. Hedges, Lauren M. Rocha, Bruno Coelho Hall-Mendelin, Sonja Day, Andrew Riegler, Markus Hugo, Leon E. Johnson, Karyn N. Kay, Brian H. McGraw, Elizabeth A. Hurk, Andrew F. van den Ryan, Peter A. O'Neill, Scott L. |
| dc.subject.en.pt_BR.fl_str_mv |
Humdisease Molimmuno |
| topic |
Humdisease Molimmuno |
| description |
University of Queensland. School of Biological Sciences. Brisbane, Australia/ Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil |
| publishDate |
2009 |
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2009 |
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2016-04-11T14:11:58Z |
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2016-04-11T14:11:58Z |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.citation.fl_str_mv |
MOREIRA, Luciano Andrade et al. A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium. Cell., vol.139, n. 7, p. 1268-78, 2009. |
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https://www.arca.fiocruz.br/handle/icict/13668 |
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0092-8674 |
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10.1016/j.cell.2009.11.042 |
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MOREIRA, Luciano Andrade et al. A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium. Cell., vol.139, n. 7, p. 1268-78, 2009. 0092-8674 10.1016/j.cell.2009.11.042 |
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Cell Press |
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Cell Press |
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